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495 articles

September 202624

Case ReportOphthalmology

Long-term natural history of spontaneous closure of a full-thickness macular hole in retinitis pigmentosa.

A middle-aged woman with retinitis pigmentosa presented with a non-tractional full-thickness macular hole. After 18 years of follow-up, the macular hole closed spontaneously, resulting in a stable lamellar configuration…

BMJ Case RepSep 24, 2026Read case
Case ReportOphthalmology

Fundus albipunctatus-like retinopathy in hypovitaminosis A-related optic neuropathy with skull hyperostosis.

A young man presented with progressive night blindness, optic neuropathy, and bilateral retinal flecks, initially thought to indicate an inherited retinal dystrophy.

BMJ Case RepSep 24, 2026Read case
Case ReportOphthalmology

Corneal ectasia in ectodermal dysplasia: Novel Tumour Protein 63-related phenotype in Rapp-Hodgkin syndrome.

A man in his 20s with genetically confirmed Rapp-Hodgkin syndrome presented with progressive visual decline in the left eye over 12 months.

BMJ Case RepSep 24, 2026Read case
Case ReportNeurology

Atypical Foster Kennedy Syndrome With Orbital Apex Involvement Secondary to Intracranial Meningiomatosis: A Case Report.

A 43-year-old man presented with left conjunctival chemosis, which was the initial sign of an atypical Foster Kennedy syndrome.

Am J Case RepSep 24, 2026Read case
Clinical ResearchOphthalmologyOpen access

Efficacy and Safety of IGF-1 Receptor Inhibitors for Thyroid Eye Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled randomized controlled trials comparing IGF-1 receptor inhibitors with placebo for thyroid eye disease (TED).

DrugsSep 24, 2026Read summary
Case ReportOphthalmology

Unilateral Iris Mass Lesions in Presumed Ocular Tuberculosis.

A 36-year-old man presented with 15 days of right-eye redness, pain, and reduced vision. Examination showed granulomatous anterior uveitis, two lobulated iris masses, and 360° posterior synechiae.

Ann Afr MedSep 24, 2026Read case
Case ReportOtolaryngology (ENT)

Inverted Papilloma Presenting as Orbital Cellulitis and Dacryocystitis.

A 66-year-old woman with psoriasis and chronic sinusitis presented with left orbital pain, proptosis, ptosis, and blurred vision, raising concern for orbital cellulitis.

Ophthalmic Plast Reconstr SurgSep 24, 2026Read case
Case ReportOphthalmology

Late Deformity of Reconstructed Eyelid From Prostaglandin-Associated Periorbitopathy.

An 80-year-old man with a previously reconstructed left upper eyelid had mild, minimally symptomatic lagophthalmos for 14.5 years.

Ophthalmic Plast Reconstr SurgSep 24, 2026Read case
Case ReportOphthalmology

Eosinophilic Granulomatosis With Polyangiitis in a Pediatric Patient With Bilateral Lacrimal Gland Swelling.

A 2-year-old boy was assessed after admission for dacryoadenitis, with six months of fluctuating bilateral upper-lid swelling, obstructive airway disease, and enlarged tonsils.

Ophthalmic Plast Reconstr SurgSep 24, 2026Read case
Case ReportOphthalmology

Kikuchi-Fujimoto Disease Presenting as Refractory Eyelid Lesions Mimicking Chalazia.

A 16-year-old male with prior biopsy-proven Kikuchi-Fujimoto disease developed recurrent lesions of both left eyelids over 2 years, initially considered chalazia.

Ophthalmic Plast Reconstr SurgSep 24, 2026Read case
Clinical ResearchOphthalmology

Prevalence, Ocular Manifestations, and Treatment Response in Postbariatric Vitamin A Deficiency: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed biochemical vitamin A deficiency after bariatric surgery and synthesized ocular manifestations, timing, and response to repletion.

Am J OphthalmolSep 24, 2026Read summary
Clinical ResearchOphthalmology

SILICONE OIL MIGRATION DURING INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTIONS: A Review of Clinical Evidence and Factors Related to Transmission.

This systematic review evaluated the incidence and mechanisms of silicone oil droplet transmission during intravitreal anti-vascular endothelial growth factor injections.

RetinaSep 23, 2026Read summary
Clinical ResearchOphthalmology

EFFECTIVENESS AND SAFETY OF BIOSIMILAR ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR FOR RETINAL DISEASES: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effectiveness and safety of biosimilar antivascular endothelial growth factor (VEGF) compared to reference anti-VEGF injections for retinal diseases.

RetinaSep 23, 2026Read summary
Clinical ResearchOphthalmology

Preclinical and clinical evaluation of systemic danegaptide for the treatment of nonproliferative diabetic retinopathy.

This phase 1b clinical trial evaluated the safety and early efficacy of danegaptide, an oral medication, in patients with nonproliferative diabetic retinopathy (NPDR) and mild center-involved macular edema.

Sci Transl MedSep 23, 2026Read summary
Case ReportOphthalmology

Peripartum Decompensation of an Orbital Vascular Malformation Managed With Urgent Postpartum Surgical Decompression.

A 36-year-old woman at 36 weeks’ gestation developed months of pain on upgaze and progressive right-eye visual loss. Examination showed 20/200 acuity, a relative afferent pupillary defect, proptosis, restricted…

Ophthalmic Plast Reconstr SurgSep 23, 2026Read case
Case ReportOphthalmology

Rare ophthalmic complication of tuberculosis meningitis: tuberculosis orbital apex syndrome.

A woman in her mid-60s presented with orbital apex syndrome, characterized by dysfunction of multiple cranial nerves. Diagnostic challenges arose due to the rarity of tuberculosis-related OAS in non-endemic regions.

BMJ Case RepSep 22, 2026Read case
Clinical ResearchOphthalmology

Efficacy of 0.01% atropine eye drops for myopia control in children of different ethnicities: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of 0.01% atropine eye drops for myopia control in children across different ethnicities.

Br J OphthalmolSep 22, 2026Read summary
Clinical ResearchOphthalmology

Treating socket discharge and discomfort: a crossover randomised trial of vitamin A ointment, low-dose steroid eyedrops and artificial tears.

This crossover randomized trial evaluated the effects of vitamin A ointment, artificial tears, and low-dose steroid drops on chronic irritation and discharge in 40 anophthalmic patients using ocular prostheses.

Br J OphthalmolSep 22, 2026Read summary
Case ReportOphthalmologyOpen access

A Novel Modification of the Yamane Intrascleral Haptic Fixation Technique with Scleral Groove-Flap Coverage: A Case Series Study.

This case series describes a modified Yamane technique for intrascleral haptic fixation in three eyes requiring secondary intraocular lens (IOL) implantation due to inadequate capsular support.

Int Med Case Rep JSep 22, 2026Read case
Clinical ResearchOphthalmologyOpen access

Comparison of Methods for Assessing Chlamydia trachomatis Transmission Intensity: A Systematic Review.

This systematic review assessed how field-graded trachomatous inflammation-follicular (TF) relates to other measures of Chlamydia trachomatis transmission intensity.

Am J Trop Med HygSep 22, 2026Read summary
Case ReportOphthalmology

Treatment of bilateral Irvine-Gass syndrome with suprachoroidal triamcinolone injection.

A woman in her 60s developed bilateral cystoid macular oedema (CME) following sequential cataract surgeries, resulting in a decline in visual acuity.

BMJ Case RepSep 21, 2026Read case
Case ReportOphthalmology

Posterior chamber phakic intraocular lens in posterior polymorphous corneal dystrophy.

A woman in her early 20s with bilateral compound myopic astigmatism and unilateral posterior polymorphous corneal dystrophy (PPCD) underwent sequential bilateral implantation of toric posterior chamber phakic…

BMJ Case RepSep 21, 2026Read case
Case ReportOphthalmology

Post-streptococcal uveitis syndrome in a middle-aged adult patient.

A 53-year-old woman developed bilateral panuveitis after a documented case of streptococcal pharyngitis. She presented with photophobia, blurred vision, and floaters.

BMJ Case RepSep 21, 2026Read case
Case ReportOphthalmology

Simultaneous Thyroid Eye Disease and IgG4-Related Orbital Disease in a Patient With Diabetes Mellitus: A Case Report.

A 72-year-old man with a history of thyroid eye disease and diabetes presented with progressive proptosis and orbital swelling.

Am J Case RepSep 21, 2026Read case

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