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2000 articles
July 202624
Efficacy and Safety of Endoscopic Treatment for Chronic Hemorrhagic Radiation Enteropathy: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of endoscopic treatments for chronic hemorrhagic radiation enteropathy in 2626 patients.
A novel MYO5C-ALK fusion in lung adenocarcinoma: limited alectinib response and durable lorlatinib benefit.
A 72-year-old never-smoker with stage IVB lung adenocarcinoma was found to have a novel MYO5C-ALK fusion. Despite initial treatment with alectinib, the tumor progressed after approximately seven months without any…
Deep learning approaches for predicting response to neoadjuvant chemotherapy in muscle invasive bladder cancer: A systematic review.
This systematic review evaluated deep learning models for predicting neoadjuvant chemotherapy response in muscle-invasive bladder cancer (MIBC).
Financial factors shaping treatment decisions in oncology: A systematic review.
This systematic review examined how financial factors influence treatment decisions in oncology, analyzing 60 studies. It found that financial incentives, particularly from industry, significantly affect prescribing…
Systematic review of antiemetic therapy for low emetogenic chemotherapy: comparing 5-HT 3 receptor antagonists and dexamethasone.
This systematic review evaluated the comparative effectiveness of 5-HT3 receptor antagonists versus dexamethasone for preventing chemotherapy-induced nausea and vomiting in adult patients receiving low-emetogenic…
Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series.
Three pediatric patients with primary cutaneous anaplastic large cell lymphoma (pcALCL) presented with skin-limited disease. They exhibited significant molecular heterogeneity, including known and novel gene fusions.
Non-vascularized bone grafting for segmental mandibular reconstruction after oral cancer resection: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness of non-vascularized bone grafts (NVBG) for segmental mandibular reconstruction post-oral cancer resection.
A systematic review of economic evidence of artificial intelligence in healthcare.
This systematic review evaluated the economic evidence of artificial intelligence (AI) technologies in healthcare, analyzing 98 unique evaluations from 91 records.
Long-term safety and efficacy of ponesimod, an oral S1P1 receptor modulator, in relapsing-remitting multiple sclerosis (RRMS): Results from randomized phase 2b core and extension studies spanning up to 13 years.
This study evaluated the long-term safety and efficacy of ponesimod in patients with relapsing-remitting multiple sclerosis (RRMS) over a period of up to 13 years, utilizing data from a randomized phase 2b trial and its…
The impact of different types of play interventions on anxiety and depressive symptoms in children with cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of play interventions on anxiety and depressive symptoms in 1541 children with cancer.
Primary Cutaneous Follicular Helper T-Cell Lymphoma: A Clinicopathological Study of Six Cases and Review of the Literature.
This study presents six cases of primary cutaneous follicular helper T-cell lymphoma (pcTFH-L), characterized by localized skin lesions in patients aged 42 to 75 years, without systemic symptoms.
Iodine Avid Muscle Metastases Mimicking Skeletal Lesions on Whole-Body Iodine Scan in Poorly Differentiated Thyroid Carcinoma -SPECT/CT to the Rescue.
A patient with poorly differentiated thyroid carcinoma (PDTC) presented with multifocal muscle metastases that were iodine-avid, leading to confusion with skeletal lesions on whole-body iodine scans.
The Association Between Human Papillomavirus and Prostate Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined epidemiological evidence on human papillomavirus (HPV) and prostate cancer.
Artificial intelligence (AI) uses in stereotactic radiosurgery (SRS): diagnosis with brain metastasis (BM) - A systematic review.
This systematic review evaluated the use of artificial intelligence (AI) in diagnosing brain metastases (BM) during stereotactic radiosurgery (SRS).
Patient-reported outcomes from the TBCRC 022 study of neratinib and ado-trastuzumab emtansine for HER2-positive breast cancer brain metastases.
The TBCRC 022 study, a Phase II multicenter clinical trial, evaluated the gastrointestinal toxicities of neratinib and ado-trastuzumab emtansine in patients with HER2-positive breast cancer brain metastases.
Nutritional support for cancer cachexia: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the effects of nutritional support on cancer cachexia in adults, analyzing 32 randomized controlled trials.
Burdened and Burned Out: Health Behavior Disruptions in Neuro-Oncology Caregivers.
This analysis of baseline survey data from a randomized controlled trial examined perceived health-behavior changes among 116 caregivers of patients with primary brain tumors.
The Role of Locoregional Treatment in Non-Progressive De Novo Metastatic Breast Cancer under Systemic Treatment: A Randomized Controlled Trial (LTMBC).
This randomized controlled trial evaluated the impact of locoregional treatment (LRT) on overall survival (OS) in 250 patients with non-progressive de novo metastatic breast cancer (DnMBC) undergoing systemic treatment.
Collision Tumor of Merkel Cell Carcinoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Cytological and Flow Cytometric Diagnostic Pitfall.
A 68-year-old male presented with right axillary lymphadenomegaly. Fine-needle cytology revealed a population of intermediate-sized lymphoid cells and larger plasmacytoid cells.
Oral and Pancreatobiliary Microbiota in Cancer: A Systematic Review of Compositional Alterations and Their Clinical Implications.
This systematic review examined microbial dysbiosis in patients with pancreatobiliary malignancies, analyzing 16 studies with 1426 participants.
Patient-reported Outcomes After Prostate Stereotactic Body Radiotherapy at 5 yr: Results from the PACE-B Trial.
The PACE-B trial, a phase 3 randomized controlled trial, evaluated patient-reported outcomes after 5 years in men with localized prostate cancer treated with stereotactic body radiotherapy (SBRT) versus conventionally…
False-Positive [¹⁸F]FET-Uptake in a Developmental Venous Anomaly: A Diagnostic Pitfall.
A 60-year-old patient with right temporal glioblastoma (WHO CNS grade 4) underwent resection and chemoradiation. Seven-month follow-up MRI showed new contrast enhancement at the resection margin.
Prognostic utility of tumor grade and IDH-mutation status for immunotherapy response in high grade glioma: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prognostic value of tumor grade and IDH-mutation status in high-grade gliomas treated with immunotherapy.
PSMA-avid Pleural Solitary Fibrous Tumor Incidentally Detected on [ 18 F] Piflufolastat PSMA PET/CT.
An 81-year-old man with biopsy-proven high-risk prostate cancer (PCa) underwent staging with [ 18 F]piflufolastat PET/CT. Imaging showed intense uptake in the prostate gland and an incidental PSMA-avid pleural lesion in…
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