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1320 articles

February 20268

Case ReportPediatrics

Pediatric-Onset Multiple Sclerosis in Multiple Autoimmune Syndrome: Reporting This Rare Entity in 2 Pediatric Patients.

The report describes two children with pediatric-onset multiple sclerosis (POMS) who also met criteria for multiple autoimmune syndrome (MAS), defined as three or more autoimmune disorders in one person.

J Child NeurolFeb 6, 2026Read case
Clinical ResearchNeurology

Sex differences in the clinical and surgical management after intracerebral hemorrhage: A post hoc analysis of the INTERACT3 clinical trial.

This post hoc analysis of the international, stepped-wedge cluster-randomised INTERACT3 trial examined sex differences in acute clinical and surgical care among 7,036 adults with intracerebral hemorrhage; 36% were…

Int J StrokeFeb 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Endovascular treatment in patients with cervical or intracranial isolated internal carotid artery occlusion: A systematic review and meta-analysis.

This systematic review and meta-analysis compared endovascular treatment (EVT) with best medical treatment (BMT) for adults with acute ischemic stroke due to isolated internal carotid artery occlusion, including…

Neuroradiol JFeb 4, 2026Read summary
Case ReportNeurology

Cytotoxic Lesion of the Corpus Callosum in a Patient with Acute-on-chronic Lithium Toxicity.

A 30-year-old woman with bipolar disorder developed impaired consciousness and myoclonus while taking lithium regularly. MRI showed a hyperintense lesion in the splenium of the corpus callosum, consistent with a…

Intern MedFeb 1, 2026Read case
Case ReportHematology

Status Epilepticus as the Initial Manifestation of Follicular Lymphoma with Leptomeningeal Dissemination.

A 44-year-old man presented with meningoencephalitis and developed status epilepticus. Evaluation showed diffuse leptomeningeal dissemination of grade 1 follicular lymphoma, despite negative cerebrospinal fluid cytology.

Intern MedFeb 1, 2026Read case
Case ReportEndocrinology

Reversible Cerebral Vasoconstriction Syndrome with Hyperthyroidism.

A 55-year-old woman presented with recurrent thunderclap headaches precipitated by bathing, showering, and the Valsalva maneuver.

Intern MedFeb 1, 2026Read case
Case ReportHematology

Severe Brain Atrophy after Allogeneic Hematopoietic Stem Cell Transplantation in a Patient Suffering from Chronic Graft-versus-host Disease.

A 30-year-old man developed brain atrophy approximately one year after allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia, most prominently affecting both medial temporal lobes.

Intern MedFeb 1, 2026Read case
Case ReportNeurology

Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) Associated with the CSF1R p. (Ile843Thr) Variant: Clinical, Imaging, and Molecular Characterization.

An adult presented with progressive cognitive and behavioral decline, followed by motor dysfunction. MRI showed predominantly frontoparietal white matter lesions and thinning of the corpus callosum, raising concern for…

Intern MedFeb 1, 2026Read case

January 202616

Clinical ResearchNeurology

Effects of Combined Psychological and Functional Exercise Interventions on Emotion, Life Quality, and Brain-Derived Neurotrophic Factor Levels in Patients With Parkinson's Disease: A Randomized Controlled Trial.

This randomized controlled trial evaluated a 12-week programme combining psychological support and functional exercise, added to routine care, in 172 patients with Parkinson’s disease.

Int J Psychiatry MedJan 29, 2026Read summary
Case ReportOncology (Medical)Open access

Progressive multifocal leukoencephalopathy associated with elranatamab therapy in relapsed/refractory multiple myeloma.

A 67-year-old woman with relapsed/refractory multiple myeloma achieved a complete response with elranatamab, a BCMA- and CD3-targeting bispecific antibody.

J Oncol Pharm PractJan 28, 2026Read case
Case ReportNeurology

What if my left hand wants to grab a cookie but my right one disagrees? A single-case study on chronic anarchic hand syndrome rehabilitation.

A 26-year-old woman developed anarchic hand syndrome (AHS) after an intracerebral hemorrhage caused by rupture of an anterior communicating artery aneurysm.

Neuropsychol RehabilJan 28, 2026Read case
Clinical ResearchNeurology

Emerging Role of Portable Accelerometers for Assessment of Gait Instability in Idiopathic Normal Pressure Hydrocephalus: A Systematic Review.

This PRISMA-guided systematic review assessed portable and smartphone-based accelerometers for measuring gait in idiopathic normal pressure hydrocephalus (iNPH).

J Geriatr Psychiatry NeurolJan 28, 2026Read summary
Clinical ResearchNeurologyOpen access

Obsessive-compulsive disorder in people with multiple sclerosis: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis examined the prevalence of obsessive-compulsive disorder (OCD) in people with multiple sclerosis (MS) and its association with MS.

Acta Neurol BelgJan 24, 2026Read summary
Clinical ResearchNeurologyOpen access

GPR3 in neuro-metabolic-immune-reproductive nexus - a potential therapeutic target for Multi-System diseases.

This systematic review examined GPR3, an orphan G-protein-coupled receptor, across neurological, metabolic, immune, and reproductive systems, drawing on a literature search of PubMed and Web of Science.

Ann MedJan 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Revisiting the Association of Pesticide Exposure and Parkinson's Disease: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis updated evidence on pesticide exposure and Parkinson’s disease (PD), examining associations by exposure type and pesticide class.

Environ ToxicolJan 21, 2026Read summary
Case ReportMedical Genetics

Efficacy of Dravet Syndrome Treatments in a Subset of Individuals with 2q24.3 Deletion: A-5 Patient Case Series.

The report qualitatively assessed treatment responses in five individuals with Dravet syndrome and 2q24.3 microdeletions involving SCN1A and other voltage-gated sodium-channel genes.

J Child NeurolJan 21, 2026Read case
Clinical ResearchNeurologyOpen access

Tai Chi modulating multimodal connectivity patterns and cognitive function in cerebral small vessel disease.

This randomized controlled trial examined whether Tai Chi affects cognition and brain connectivity in 51 patients with cerebral small vessel disease (CSVD).

GeroscienceJan 21, 2026Read summary
Clinical ResearchNeurology

Optical coherence tomography retinal biomarkers for traumatic brain injuries: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed OCT-derived retinal measures as potential biomarkers of traumatic brain injury (TBI), comparing people with TBI and controls across seven studies of athletes, veterans…

Clin Exp OptomJan 21, 2026Read summary
Clinical ResearchNeurology

The Effect of Vagus Nerve Stimulation on the Rehabilitation of Stroke: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis pooled 16 randomized controlled trials involving 819 patients with stroke to assess vagus nerve stimulation (VNS) alongside rehabilitation.

Arch Phys Med RehabilJan 20, 2026Read summary
Clinical ResearchNeurologyOpen access

Comparative effects of pharmacological interventions in the prophylactic treatment of tension-type headache: systematic review and network meta-analysis.

This systematic review and network meta-analysis compared medications for preventing tension-type headache (TTH), using randomized controlled trials identified through searches to December 12, 2025.

Ann MedJan 18, 2026Read summary
Clinical ResearchUrology

Evaluation of Functional Magnetic Stimulation Parameters and Effectiveness for Neurogenic Detrusor Overactivity: A Systematic Review and Network Meta-Analysis.

This systematic review and network meta-analysis compared functional magnetic stimulation (FMS) protocols for neurogenic detrusor overactivity (NDO) in 20 randomized controlled trials involving 1,316 participants.

NeuromodulationJan 16, 2026Read summary
Clinical ResearchGeriatrics

Associations of Physical Activity Trajectories With Transitions Across Cognitive States: A Multinational Cohort Study.

This multinational cohort study examined whether physical activity (PA) trajectories were associated with transitions among no cognitive impairment, mild cognitive impairment (MCI), and dementia in data from HRS, ELSA…

Am J Geriatr PsychiatryJan 15, 2026Read summary
Case ReportNeurology

Deep Cerebral Venous Thrombosis Presenting with Korsakoff Syndrome.

A patient with deep cerebral venous thrombosis (DCVT) initially presented with Korsakoff syndrome. Imaging showed edematous lesions in both thalami, linking the amnestic syndrome to thalamic involvement.

Intern MedJan 15, 2026Read case
Case ReportNeurology

Bickerstaff Brainstem Encephalitis with a Decorticate-like Posture, Involuntary Movements, Impaired Visual Acuity, and Prolonged Motor Disability.

A Japanese patient with Bickerstaff brainstem encephalitis presented with a decorticate-like posture, involuntary movements, and impaired visual acuity—features that obscured the usual clinical picture.

Intern MedJan 15, 2026Read case

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