Trending archive
Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.
2000 articles
November 202618
Transformation to Small-Cell Lung Carcinoma and Then to Sarcomatoid Carcinoma in an EGFR-Mutant Lung Adenocarcinoma Patient During Systemic Therapy: A Case Report.
A patient with EGFR-mutant lung adenocarcinoma developed resistance to osimertinib with transformation to combined small-cell lung carcinoma.
Added Value of Preoperative Contrast Enhanced Mammography in Staging of Malignant Breast Lesions (PROCEM): A Randomized Controlled Trial.
This prospective, multicenter randomized controlled trial evaluated whether preoperative contrast-enhanced mammography (CEM) adds value to standard imaging for staging early-stage breast cancer in women eligible for…
Biomarker Modulation by Aspirin and Metformin for Colorectal Cancer Prevention: Results from the ASAMET Randomized Phase II Trial.
The multicenter, double-blind, 2 × 2 factorial phase II ASAMET randomized trial evaluated aspirin, metformin, and their combination for 12 months in patients with resected stage I to III colorectal cancer.
Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial.
This multicenter randomized clinical trial tested whether routine cardiovascular-specialist referral improved risk-factor control and cardiovascular outcomes in patients with prostate cancer who were starting or had…
Eltrombopag during induction chemotherapy in older patients with newly diagnosed acute myeloid leukemia is safe and reduces platelet transfusion requirements: The EPAG-2015 French Innovative Leukemia Organization phase 2 randomized trial.
The multicentre, phase 2 randomized trial EPAG-2015 evaluated eltrombopag started after induction chemotherapy in patients aged 60 years or older with newly diagnosed acute myeloid leukemia.
A multicenter, prospective, phase 2 trial on proton re-irradiation for patients with previously treated head and neck cancer.
This multicenter, prospective phase 2 trial evaluated proton re-irradiation in patients with previously irradiated head and neck cancer.
Ascites Presenting as a Peritonitis-Like Manifestation and Liver Injury due to Trabectedin Monotherapy in a Patient With Myxoid Liposarcoma.
An 82-year-old woman with recurrent metastatic myxoid liposarcoma developed liver dysfunction and ascites while receiving trabectedin monotherapy, after 12 cycles.
Optimal Exercise Dose for Improving Multidimensional Health Outcomes in Colorectal Cancer Patients: A Systematic Review, Meta-Analysis and Meta-Regression.
This systematic review, meta-analysis and meta-regression examined exercise dose-response relationships in colorectal cancer patients.
LEgal Guidance for Cancer Patients and CAREgivers (LEGACY CARE): A Pilot Clinical Trial.
This single-arm pilot clinical trial evaluated the feasibility and acceptability of proactive legal care for patient-caregiver dyads affected by advanced-stage colorectal cancer.
Therapeutic Approaches and Clinical Outcomes of Myeloid/Lymphoid Neoplasms With Eosinophilia Harboring FLT3 Rearrangements: A Systematic Review of 39 Cases.
This systematic review examined treatment approaches and outcomes in 39 reported cases of myeloid/lymphoid neoplasms with eosinophilia harboring FLT3 rearrangements, a rare malignancy without standardized treatment…
Phase 2 Trial of 89 Zr-Deferoxamine-Daratumumab for CD38-targeted Immuno-PET/CT Detection of Multiple Myeloma.
This prospective phase 2 trial compared CD38-targeted 89Zr-DFO-daratumumab immuno-PET/CT with standard-of-care 18F-FDG PET/CT in 60 participants with multiple myeloma.
Paraneoplastic Autoimmune Multiorgan Syndrome: Diagnostic Lessons for Pediatricians.
An 11-year-old boy developed subacute erythroblastopenia, followed by polymorphic mucocutaneous findings, severe myositis with a dermatomyositis-like phenotype, and mild hepatitis.
Paxalisib with Trastuzumab for HER2-Positive Metastatic Breast Cancer with Active Brain Metastases: A Phase II Trial with Integrated Plasma and CSF ctDNA Analyses.
This phase II trial evaluated brain-penetrant paxalisib plus trastuzumab in patients with active or progressive HER2-positive breast cancer brain metastases, including heavily pretreated patients; leptomeningeal disease…
Liposomal irinotecan and capecitabine plus bevacizumab as second-line therapy in metastatic colorectal cancer: A multicenter, single-arm study.
This multicenter, single-arm clinical study evaluated liposomal irinotecan, capecitabine, and bevacizumab as second-line therapy in patients with metastatic colorectal cancer progressing after oxaliplatin-based…
Non-Small Cell Lung Carcinoma With Bilayered Architecture and TP53 Alteration: A Diagnostic Pitfall and a Potential Distinct Entity.
A 75-year-old never-smoker had a 1.1-cm pulmonary nodule with an intact bilayered architecture, including a continuous basal cell layer.
Preoperative Temporal Elevation of Cytokeratin 19 Fragment in Thymoma With Extensive Necrosis: A Case Report.
A 73-year-old man presented with chest pain, and CT showed a mediastinal mass with pleural effusion. White blood cell count, C-reactive protein, and cytokeratin 19 fragment (CYFRA) were elevated; CYFRA was 61.3 ng/mL.
Pembrolizumab Activity in Tyrosine Kinase Inhibitor-Refractory Metastatic GIST: A Case Report.
A man with epithelioid small-bowel GIST developed liver metastases seven years after diagnosis. The tumor carried a primary KIT exon 11 D579del mutation, a secondary KIT exon 17 D820G mutation, and CDKN2A/CDKN2B…
Assessing the reproductive lifespan of female cancer survivors using AMH: a meta-synthesis of longitudinal studies.
This systematic review and meta-synthesis quantified AMH changes after cancer treatment in female survivors and compared longer-term trajectories with age-matched controls.
October 20266
Early functional deterioration during first-line ICI-based therapy in advanced NSCLC: implications for supportive care.
This secondary exploratory analysis of prospectively collected data from a randomized pulmonary rehabilitation trial assessed early functional change in 42 people receiving first-line immune checkpoint inhibitor–based…
Efficiency of different approaches in teaching tracheal suctioning procedure to caregivers of tracheostomy patients: randomized controlled study.
This randomized controlled study compared simulation-based and mobile application training with routine bedside instruction for primary caregivers of people with tracheostomies, including patients with head and neck…
Local ablative treatment for oligoprogression during immunotherapy in metastatic non-small-cell lung cancer: a systematic review and meta-analysis.
This PRISMA-compliant systematic review and meta-analysis assessed local ablative treatment (LAT), with continuation of the same immune checkpoint inhibitor, for oligoprogressive or oligo-resistant metastatic NSCLC…
Unmasking Panic Disorder in Adults with Leukemia: A Systematic Review of Prevalence, Risk Factors, and Management.
This PRISMA-guided systematic review examined panic disorder and anxiety in adults with leukemia, searching four databases for studies published from 2015 to July 20, 2025.
Phase 1 Study of Safety and PK With A Combination of Omeprazole and Trimetazidine for Fatty Acid Oxidation Inhibition in Patients With Advanced Solid Tumors.
This Phase I, open-label, 3 + 3 dose-escalation study assessed safety, tolerability, pharmacokinetics, and preliminary antitumor activity of once-daily oral omeprazole plus trimetazidine, two fatty acid oxidation…
Endpoint-specific mortality associated with malignancy among adults with sepsis or septic shock: a systematic review and meta-analysis.
This systematic review and meta-analysis examined mortality among adults with sepsis or septic shock, comparing patients with and without malignancy.
Showing the most recent matches. Add a word or a date to reach older ones.
Stay updated for free
Get the 3 most interesting publications in one specialty each week.
Weekly email. Unsubscribe anytime.
Want this personalized?
Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.
- Your specialties
- Your filters and thresholds
- Clinical Research + Case Reports, tuned separately
- Automatic weekly delivery
- Audio and text
Prefer listening? Personalized audio digests are available with Pro.