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1303 articles

January 202617

Clinical ResearchPsychiatryOpen access

The Effect of Creatine Monohydrate on Mental Disorders: A Systematic Review of Randomized Controlled Trials: Effet du monohydrate de créatine sur les troubles mentaux : examen systématique des essais contrôlés à répartition aléatoire.

This systematic review evaluated randomized controlled trials of creatine monohydrate for psychiatric symptoms and safety in people with mental disorders.

Can J PsychiatryJan 20, 2026Read summary
Clinical ResearchCardiology

A Causal Association Between Atrial Fibrillation and Depression: Evidence From Mendelian Randomization Analyses.

This two-sample Mendelian randomization study examined whether atrial fibrillation (AF) is causally associated with depression, using genetic data from separate AF and depression genome-wide association studies and a…

Int J Psychiatry MedJan 20, 2026Read summary
Clinical ResearchPsychiatryOpen access

The efficacy and mechanism of an integrated mindfulness-based programme on posttraumatic stress disorder among people with HIV: a randomized controlled trial with 3-month follow up.

This randomized controlled trial evaluated an Integrated Mindfulness-Based Programme (IMBP), combining the Community Resiliency Model and mindfulness-based stress reduction, in 82 people with HIV and PTSD.

Eur J PsychotraumatolJan 19, 2026Read summary
Clinical ResearchPsychiatryOpen access

The Relationship Between Family History of Depression and Brain Structure and Function: A Systematic Review of Large Cohorts.

This systematic review identified existing longitudinal cohorts suitable for studying associations between family history of major depression and brain imaging outcomes.

Biol PsychiatryJan 15, 2026Read summary
Clinical ResearchPsychiatry

Measuring secondary traumatic stress in therapists: A systematic review.

This systematic review examined how secondary traumatic stress (STS) is measured in therapy-offering mental health clinicians.

Psychol TraumaJan 15, 2026Read summary
Clinical ResearchPsychiatryOpen access

Genomic Studies of Suicidal Thoughts and Behaviors in Latin American Populations: A Systematic Review.

This systematic review synthesized molecular studies of suicidal ideation, suicide attempts, nonsuicidal self-injury, and suicide death among Latin American or Hispanic/Latinx populations.

Biol PsychiatryJan 13, 2026Read summary
Clinical ResearchPsychiatry

Reward-related neural activity after low doses of LSD in participants with depressed mood.

This randomized, placebo-controlled study examined reward-related event-related potentials (ERPs) after low-dose LSD in participants with subclinical mild-to-moderate depressed mood (N = 20) and controls with minimal…

J PsychopharmacolJan 13, 2026Read summary
Clinical ResearchPsychiatryOpen access

Greater reactivity to stressors as an indicator of service utilization and need in veteran women with sexual assault histories.

This study examined whether stressor reactivity was associated with service use and resource needs among 153 veteran women with sexual assault histories who participated in a randomized clinical trial.

Psychol ServJan 12, 2026Read summary
Clinical ResearchGeriatricsOpen access

Systematic Reviews of Psychosocial Interventions for Loneliness Among Older Adults in Community and Residential Care Settings: An Umbrella Review.

This umbrella review, conducted using Joanna Briggs Institute methodology, examined psychosocial interventions for loneliness among older adults in community and residential care settings.

J Adv NursJan 9, 2026Read summary
Clinical ResearchGeriatrics

Barriers and Facilitators for the Adaptation and Implementation of Cognitive Stimulation Therapy: A Systematic Review.

This systematic review examined barriers and facilitators encountered when adapting or implementing Cognitive Stimulation Therapy (CST) across countries.

J Geriatr Psychiatry NeurolJan 9, 2026Read summary
Clinical ResearchGeriatrics

Intervention Without Borders - an Automated Self-Guided AI-Enhanced Psychoeducation Intervention for Dementia Caregivers: Parallel-Group Randomized Waitlist-Controlled Trial.

This parallel-group randomized waitlist-controlled trial evaluated PDC30, a fully automated, self-guided online psychoeducation intervention, in 274 caregivers from 43 countries.

Am J Geriatr PsychiatryJan 8, 2026Read summary
Clinical ResearchPsychiatry

Precision Optimization of Behavioral Activation for Major and Subthreshold Depression: A Meta-Analysis of Exploring Dose-Response Relationships and Moderating Factors.

This meta-analysis of randomized controlled trials assessed behavioral activation (BA) for adolescents with subthreshold depression or major depressive disorder.

J Am Acad Child Adolesc PsychiatryJan 5, 2026Read summary
Clinical ResearchPsychiatry

Cognitive reactivity and dysfunctional attitudes in cognitive behavioral and psychodynamic therapy for adult depression.

This randomized controlled trial examined whether cognitive reactivity (CR) changes during treatment for depression and whether baseline CR or dysfunctional attitudes (DA) relate to outcome.

Psychother ResJan 5, 2026Read summary
Clinical ResearchPsychiatryOpen access

Neurofeedback as an Adjunct to Pharmacotherapy in OCD: A Randomized Controlled Trial on Symptom Reduction.

This single-blind randomized clinical trial evaluated neurofeedback added to pharmacotherapy in 45 patients with obsessive-compulsive disorder (OCD), assigned equally to neurofeedback, placebo-procedure, or…

Appl Psychophysiol BiofeedbackJan 3, 2026Read summary
Clinical ResearchPsychiatry

Stalking behaviors and Personality Disorders: A systematic review.

This systematic review examined personality disorders (PDs) in mixed clinical-forensic populations with stalking behavior. Following a search of Medline/PubMed and Scopus, 12 papers were included from an initial 200…

Clin TerJan 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Imagery Interventions and Cognitive-Behavioural Therapy for Psychological Complaints Related to Bullying: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed individual cognitive-behavioural therapy (CBT) and imagery interventions for bullying victims, examining internalizing symptoms, self-perception and coping.

Clin Psychol PsychotherJan 1, 2026Read summary
Clinical ResearchPsychiatry

An Updated Systematic Review and Meta-Synthesis of Service User's Experiences of Cognitive Behavioural Therapy for Psychosis (CBTp).

This pre-registered thematic meta-synthesis integrated qualitative research on service users’ experiences of cognitive behavioural therapy for psychosis (CBTp). Searches identified 24 studies involving 334 participants.

Clin Psychol PsychotherJan 1, 2026Read summary

December 20257

Clinical ResearchPsychiatry

Mind the gap: a systematic review of depression, barriers, and facilitators to mental health care after miscarriage.

This systematic review examined depressive symptoms and access to mental health care after miscarriage, comparing evidence for women in general care settings and those with recurrent pregnancy loss.

J Psychosom Obstet GynaecolDec 31, 2025Read summary
Clinical ResearchPsychiatry

Transcriptional Signatures of Mitochondrial Metabolism Predict Esketamine-Induced rACC Structural Changes in Adolescent Major Depression.

This randomized controlled trial examined whether esketamine-related changes in the rostral anterior cingulate cortex (rACC) were associated with clinical improvement and molecular pathways in adolescents aged 13–18…

J Am Acad Child Adolesc PsychiatryDec 31, 2025Read summary
Clinical ResearchPsychiatry

Meta-Analysis: Parenting Children and Adolescents With Attention-Deficit/Hyperactivity Disorder Compared to Healthy Controls.

This systematic review and meta-analysis compared parenting practices in families of children and adolescents (≤18 years) with specialist-confirmed ADHD and non-clinical controls.

J Am Acad Child Adolesc PsychiatryDec 30, 2025Read summary
Clinical ResearchGeriatricsOpen access

Factors Affecting Well-Being and Quality of Life From the Perspective of People With Moderate-To-Severe Dementia: A Qualitative Evidence Synthesis.

This systematic review and qualitative thematic synthesis examined what people with moderate-to-severe dementia consider important for well-being and quality of life.

Dementia (London)Dec 29, 2025Read summary
Clinical ResearchPsychiatry

Interventions targeting executive functions in children and young people exposed to complex trauma: A systematic review.

This PRISMA-guided systematic review examined interventions targeting executive function (EF) in children and young people exposed to complex trauma, including abuse, neglect, and violence.

Neuropsychol RehabilDec 26, 2025Read summary
Clinical ResearchPsychiatryOpen access

Efficacy of Brexpiprazole on Neuropsychiatric Symptoms and Impact on Caregivers: Pooled Neuropsychiatric Inventory (NPI) Analysis in Patients With Agitation Associated With Dementia due to Alzheimer's Disease.

This exploratory pooled analysis examined Neuropsychiatric Inventory (NPI) outcomes from two randomized, double-blind, placebo-controlled trials of brexpiprazole for agitation associated with Alzheimer’s disease…

J Geriatr Psychiatry NeurolDec 24, 2025Read summary
Clinical ResearchPsychiatryOpen access

Improving Community-Based Care for Adolescents with ADHD: a Randomized Controlled Trial of Artificial Intelligence-Assisted Fidelity Supports.

This randomized controlled trial evaluated whether AI-assisted implementation supports improved delivery of Supporting Teens’ Autonomy Daily (STAND), a cognitive-behavioral treatment blended with Motivational…

Prev SciDec 24, 2025Read summary

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