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1320 articles
May 20264
Reporting quality and evidence support in randomized controlled trials of Bupleurum-based herbal medicine formulas for epilepsy.
This meta-analysis evaluated the efficacy of Bupleurum-based herbal formulas in treating epilepsy, analyzing 33 randomized controlled trials with 2464 patients.
Comparing the Effects of Cognitive and Physical Training on Cognitive Function and Brain Activation in People With Mild Cognitive Impairment and Mild Dementia: A Randomized Controlled Trial.
This randomized controlled trial evaluated the effects of cognitive training (CT) and physical training (PT) on cognitive function and brain activation in older adults with mild cognitive impairment or mild dementia.
Goal setting in stroke rehabilitation: A systematic review and qualitative synthesis of the experiences and perspectives of healthcare professionals.
This systematic review and qualitative synthesis examined healthcare professionals’ experiences and perspectives on goal setting in stroke rehabilitation.
Costs and cost effectiveness of the use of telerehabilitation training for upper limb function in people after stroke: A systematic review.
This systematic review examined costs and cost-effectiveness of technology-based telerehabilitation for upper limb function after stroke.
April 202620
Efficacy and safety of Mudan granules for treatment of diabetic peripheral neuropathy: a multicenter, double-blind, placebo-controlled, randomized, clinical trial.
This multicenter, double-blind, placebo-controlled randomized trial evaluated the efficacy and safety of Mudan granules in 400 patients with diabetic peripheral neuropathy (DPN).
Clinical, Behavioral and Neuroradiological Phenotype in an Italian Cohort of Patients With Xia Gibbs Syndrome: A Multicenter Cross-Sectional Study and Systematic Literature Review.
This multicenter cross-sectional study examined 15 patients with Xia Gibbs Syndrome (XGS) due to heterozygous AHDC1 variants.
FGF12-Related Early-Onset Epileptic Encephalopathies: Therapeutic Response to Sodium Channel Blockers.
Developmental and epileptic encephalopathies (DEEs) comprise a clinically and genetically heterogeneous group of severe neurodevelopmental disorders, frequently caused by pathogenic variants in genes encoding neuronal…
Effects of physical exercise on spasticity in people with multiple sclerosis: A systematic review.
This systematic review examined whether physical exercise reduces spasticity in people with multiple sclerosis (MS). It included 13 randomised controlled trials enrolling participants with EDSS scores ≤6.0 and…
Early-Onset Epileptic Encephalopathy and Neurodevelopmental Regression Associated With ST3GAL5 Deficiency.
A Turkish male infant presented with developmental delay and hypotonia, progressing to refractory epilepsy and neurodevelopmental regression.
The Efficacy of Proprioceptive Neuromuscular Facilitation-Based Robot-Assisted Therapy in Individuals With Stroke: A Randomized Controlled Trial.
This randomized controlled trial evaluated the effects of proprioceptive neuromuscular facilitation (PNF)-based robot-assisted therapy (RAT) on upper extremity motor performance, spasticity, activities of daily living…
The effects of the PDE4 inhibitor roflumilast on cognitive performance after a cerebrovascular accident: a double-blind randomized placebo-controlled trial with an open label extension (ROSTMEMA).
This double-blind randomized placebo-controlled trial evaluated the effects of the PDE4 inhibitor roflumilast on cognitive performance in 100 post-stroke patients aged 41-70 with memory complaints.
Prebiotics/synbiotics as natural alternatives for brain development and aging - focus on nutrigenomic and direct effects: a systematic review.
This systematic review examines the role of prebiotics and synbiotics in brain development and neurodegenerative diseases, analyzing 79 studies including human and animal research.
Effects of Olfactory Training on Olfactory Bulb Volume Among Patients With Non-Sinonasal-Related Olfactory Dysfunction: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of olfactory training (OT) on olfactory bulb volume (OBV) in patients with non-sinonasal-related olfactory dysfunction.
Osteopathic manipulative treatment and cervicogenic headache: a randomized controlled trial.
This randomized controlled trial evaluated osteopathic manipulative treatment (OMT) for cervicogenic headache in 413 patients allocated to findings-based OMT or standardized sham treatment.
Tubulinopathy Case Series: Marked Intrafamilial Phenotypic Variability Associated With a Novel Missense TUBB Variant.
A family with a novel missense variant in the TUBB gene presented with significant intrafamilial phenotypic variability. The proband exhibited severe symptoms, including seizures and developmental delay from 6 months…
Care navigation for older adults after stroke - A systematic review and meta-analyses to guide social prescribing.
This systematic review and meta-analysis evaluated the impact of care navigation on anxiety, depression, quality of life, and well-being in older adults (60+) post-stroke.
Neurological Puzzles After Radiotherapy: Mysterious Clues of Smart Syndrome, Two Case Reports.
This report discusses two patients who developed SMART syndrome, presenting with stroke-like symptoms and migraine-like headaches years after undergoing brain radiotherapy.
Efficacy of immersive virtual reality-based self-managed naming therapy for chronic post-stroke aphasia: A randomized controlled trial.
This randomized, single-blind, parallel-group controlled trial compared immersive virtual reality-based self-managed naming therapy with conventional therapy in 102 adults aged 40–80 years with chronic non-fluent…
Comparative evaluation of oxidative stress biomarkers F2-isoprostanes and 8-OHdG in Parkinson's disease and Type 2 Diabetes Mellitus: a systematic review and meta-analysis of human studies.
This systematic review and meta-analysis evaluated oxidative stress biomarkers F2-isoprostanes and 8-OHdG in individuals aged ≥ 50 years with Type 2 Diabetes Mellitus (T2DM) and Parkinson's Disease (PD).
Cognition in adults with cerebral palsy: A systematic review.
This systematic review synthesized studies of cognitive functioning in adults with cerebral palsy (CP), including evidence on cognitive domains, screening tools, age-related change, associated factors, and…
Experiences of Migraine and Erenumab Treatment in Japan: Qualitative Interviews with Clinical Trial Participants.
This qualitative study explored the experiences of 41 adults with migraine in Japan who participated in a phase III randomized controlled trial of erenumab.
Dysphagia in behavioural variant of frontotemporal dementia- a systematic review.
This systematic review examined how dysphagia is identified and described in people with behavioural variant frontotemporal dementia (bvFTD).
Diplopia and papilledema secondary to thrombosis of the longitudinal venous sinus due to Leiden factor V thrombophilia in a young patient.
A five-year-old girl presented with acute irritability, somnolence, headache, and diplopia. Examination showed preserved vision, marked esotropia with a sixth-nerve palsy, and papilledema.
CACNA1C -Related Channelopathy Presenting With Adult-Onset Combined Dystonia-Parkinsonism: A Novel Neurological Presentation.
A 66-year-old woman presented with combined dystonia-parkinsonism, including painful tremulous cervical dystonia, blepharospasm, divergent strabismus, hypomimia, mild left-hand dystonic posturing, action tremor, and…
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