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1320 articles

May 202624

Clinical ResearchNeurology

A tailored cognitive behavioural therapy intervention for depression in those newly diagnosed with multiple sclerosis (ACTION-MS): A randomised, assessor-blinded, active comparator trial.

The ACTION-MS trial evaluated a tailored cognitive behavioural therapy (CBT) intervention for depression in 60 individuals newly diagnosed with multiple sclerosis (MS).

J Affect DisordMay 13, 2026Read summary
Clinical ResearchNeurology

Advancing Upper Limb Motor Recovery in Acute Ischemic Stroke With Transcutaneous Auricular Vagus Nerve Stimulation.

This randomized controlled trial evaluated the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) in 60 patients with acute ischemic stroke.

Arch Phys Med RehabilMay 13, 2026Read summary
Clinical ResearchNeurologyOpen access

Transcranial Magnetic Stimulation as a Translational Biomarker in Early-Phase Anti-Seizure Medication Development: A Randomized, Double-Blind, Placebo-Controlled Study in Generalized Epilepsy.

This randomized, double-blind, placebo-controlled study evaluated transcranial magnetic stimulation (TMS) as a biomarker for anti-seizure medication effects in patients with generalized epilepsy.

Clin Pharmacol TherMay 13, 2026Read summary
Case ReportNeurology

Carotid cavernous fistula in a young adult with Bannayan-Riley-Ruvalcaba syndrome.

A 22-year-old male with Bannayan-Riley-Ruvalcaba syndrome presented with acute unilateral eyelid swelling and chemosis, without any history of trauma or visual deficits.

OrbitMay 11, 2026Read case
Clinical ResearchCardiology

Randomized Clinical Trial Comparing Effects of Pulsatile vs Nonpulsatile Cardiopulmonary Bypass on Neurologic Outcomes.

This randomized controlled trial evaluated the effects of pulsatile versus nonpulsatile cardiopulmonary bypass on S100B levels and neurological outcomes in pediatric patients undergoing congenital heart surgery.

Ann Thorac SurgMay 11, 2026Read summary
Case ReportInfectious Diseases

Construction of a "three-stage and four-level" evaluation system for cerebrospinal fluid pathogens based on mNGS: insights from a case of co-detection of Cryptococcus and Epstein-barr virus.

A patient with central nervous system symptoms underwent metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF), revealing co-detection of Cryptococcus and Epstein-Barr virus (EBV).

Diagn Microbiol Infect DisMay 8, 2026Read case
Clinical ResearchPediatricsOpen access

Memantine for Prevention of Cognitive Late Effects in Children and Adolescents Receiving Radiation Therapy for Brain Tumors: A Randomized, Controlled, Pilot Trial.

This randomized, double-blind, placebo-controlled pilot trial assessed the feasibility, acceptability, and preliminary efficacy of memantine for preventing cognitive late effects in children and adolescents receiving…

Int J Radiat Oncol Biol PhysMay 8, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Efficacy of Immersive Virtual Reality for Improving Upper Limb Motor Function in Patients With Central Nervous System Disorders: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed immersive virtual reality (VR) for upper-extremity outcomes in people with central nervous system disorders.

Am J Phys Med RehabilMay 8, 2026Read summary
Case ReportNeurology

Sequential efgartigimod-rituximab therapy in autoimmune nodopathy: A feasibility report on shortening the washout interval for B-cell depletion.

A patient with anti-CASPR1 antibody-mediated autoimmune nodopathy, unresponsive to standard treatments like intravenous immunoglobulin and plasma exchange, received a novel sequential therapy of efgartigimod followed by…

J NeuroimmunolMay 7, 2026Read case
Clinical ResearchNeurology

Time to Resume Oral Anticoagulant Therapy in Traumatic Intracranial Hemorrhage Patients, Balancing Recurrence, Thromboembolism, and Mortality: A Systematic Review.

This systematic review examined when to resume oral anticoagulant therapy (OAC) after traumatic intracranial hemorrhage (ICH) and the associated hemorrhagic, thromboembolic, and mortality outcomes.

J Head Trauma RehabilMay 7, 2026Read summary
Case ReportHematology

Central nervous system involvement in multiple myeloma as a first manifestation of relapse and potential diagnostic pitfall.

In a review of 459 patients with multiple myeloma, four had cerebrospinal fluid involvement by malignant plasma cells. Three were in complete remission when CNS disease was detected.

Cytometry B Clin CytomMay 7, 2026Read case
Case ReportInfectious Diseases

Peripheral neurological involvement due to Bartonella henselae in an immunocompetent adolescent: a case report and literature review.

A 17-year-old immunocompetent male presented with bilateral facial palsy, paresthesia, and absent deep tendon reflexes after experiencing axillary lymphadenopathy from cat scratches.

Diagn Microbiol Infect DisMay 6, 2026Read case
Case ReportPediatrics

Neurologic Presentations of Pediatric Intussusception Lead to Diagnostic Delay and Increased Need for Surgery.

A 2-year-old boy presented with orofacial dyskinesias and upper-extremity jerks, initially misdiagnosed as tardive dyskinesia. Despite normal neurological examination and brain MRI, he developed bilious vomiting.

Am SurgMay 6, 2026Read case
Case ReportNeurologyOpen access

Clinical and pathological findings in two Italian siblings of Romani ancestry with charcot-marie-tooth type 4D and review of the current literature.

A 38-year-old man and his 40-year-old sister, both of Romani ancestry, had CMT4D associated with a homozygous NDRG1 p.(Arg148*) variant.

J Neuromuscul DisMay 6, 2026Read case
Clinical ResearchGeriatrics

Multimodal intervention benefits: Responder analysis of J-MINT PRIME Kanagawa trial.

The J-MINT PRIME Kanagawa trial, a randomized controlled trial, explored a multimodal intervention for dementia prevention in 188 older adults.

Arch Gerontol GeriatrMay 5, 2026Read summary
Clinical ResearchNeurology

Mothership and Drip-and-Ship Strategies in Mechanical Thrombectomy for Acute Ischemic Stroke.

This systematic review and meta-analysis evaluated the effectiveness of mothership versus drip-and-ship strategies for acute ischemic stroke due to large vascular occlusion in 25,005 patients.

Ann Emerg MedMay 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Prognostic Value of Natriuretic Peptides for Delayed Cerebral Ischemia and Outcomes After Aneurysmal Subarachnoid Hemorrhage: An Updated-Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined observational studies of natriuretic peptide (NP) levels measured within 7 days of aneurysmal subarachnoid hemorrhage (aSAH) and their association with delayed cerebral…

Neurocrit CareMay 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Prophylactic Antiepileptic Drugs in Nontraumatic Intracerebral Hemorrhage: A Network Meta-Analysis.

This systematic review and Bayesian network meta-analysis compared prophylactic antiepileptic drugs (AEDs) with one another or control in adults with nontraumatic intracerebral hemorrhage (ICH).

Neurocrit CareMay 5, 2026Read summary
Clinical ResearchNeurology

Impact of Task-Oriented Training on Health Outcomes in Multiple Sclerosis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined task-oriented training (TOT) for health outcomes in adults with multiple sclerosis, drawing on randomized controlled trials.

Am J Phys Med RehabilMay 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Effectiveness of vestibular physical therapy on balance and dizziness in people with multiple sclerosis: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed vestibular physical therapy (VPT) for balance and dizziness in people with multiple sclerosis (PwMS).

J Vestib ResMay 5, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Transcranial Direct Current Stimulation Combined With Balance Training for Chronic Ankle Instability: A Double-Blind, Pilot Randomized Controlled Trial.

This double-blind pilot randomized controlled trial evaluated whether active transcranial direct current stimulation (tDCS) added benefit to balance training in 19 individuals with chronic ankle instability.

J Sport RehabilMay 5, 2026Read summary
Clinical ResearchPediatricsOpen access

Global Pediatric Stroke Epidemiology: A Systematic Review of the Literature and Meta-Analysis.

This systematic review and meta-analysis assessed the global burden of pediatric stroke, revealing a birth prevalence of perinatal stroke at 21.01 per 100,000 total births and a childhood incidence of stroke at 3.73 per…

J Child NeurolMay 4, 2026Read summary
Case ReportInfectious DiseasesOpen access

Infliximab in a Child With Relapsing Tuberculous Meningoencephalitis: A Case Report and Literature Review.

A 5-year-old child with tuberculous meningoencephalitis experienced severe drug-induced hepatitis following standard antitubercular therapy, leading to the discontinuation of treatment.

Pediatr Infect Dis JMay 4, 2026Read case
Case ReportNeurology

Transcutaneous Spinal Cord Stimulation for Spasticity in Primary Lateral Sclerosis: A Case Series.

This case series involved six participants with primary lateral sclerosis (PLS) who underwent a single 30-minute session of transcutaneous spinal cord stimulation (tSCS).

J Neurol Phys TherMay 4, 2026Read case

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