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557 articles
October 202624
Approach to the patient with APS-1/APECED.
This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.
Variability in belumosudil exposure due to coadministration of voriconazole and isavuconazole in a patient with chronic graft-versus-host disease: Case report.
A man in his 50s with steroid-refractory pulmonary chronic graft-versus-host disease after cord blood transplantation received belumosudil, increased from 200 mg once daily to 200 mg twice daily.
Mixed Pneumonia with Pulmonary Embolism and Multiple Pathogens Detected in Bronchoalveolar Lavage Fluid: A Case Report.
A 72-year-old man presented with fever, nonproductive cough, vomiting, hypoxemia, elevated inflammatory markers, and an elevated D-dimer.
Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.
Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.
The effects of multiregional fascial mobilization on heart rate and physiological parameters in patients with obstructive sleep apnea: A randomized controlled trial.
This randomized controlled trial assessed the acute physiological effects of a 16-minute multiregional fascial mobilization protocol in 95 men with polysomnography-confirmed moderate-to-severe obstructive sleep apnea.
Influenza A (H1N1) virus infection complicated by checkpoint inhibitor pneumonitis: A case report.
After neoadjuvant immunotherapy, a patient developed respiratory dysfunction and progressive pulmonary lesions. Imaging and positive influenza A (H1N1) testing, interpreted alongside the immunotherapy history and…
Efficacy and Safety of Necitumumab and Pembrolizumab Combination Therapy in Advanced Non-Small Cell Lung Cancer with ≥50% PD-L1 Expression: A Nonrandomized Phase II Trial.
This nonrandomized, multicenter, open-label, single-arm phase II trial evaluated first-line pembrolizumab plus necitumumab in 50 patients with previously untreated advanced NSCLC and PD-L1 tumor proportion score ≥50%.
Effects of stellate ganglion blockade on pulmonary artery pressure and sympathetic baroreflex function at high altitude: a case study in treated hypertension.
A 44-year-old man with treated hypertension underwent physiological assessment at sea level and after 5–8 days at 3,800 m. High-altitude exposure was accompanied by increases in pulmonary artery systolic pressure…
Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.
Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.
A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.
Improvement in peripheral airway function after a 12-week exercise intervention in COPD.
This prospective, multicenter, single-arm non-randomized intervention study assessed lung function, exercise capacity and symptoms before and after a 12-week supervised exercise program in 62 people with COPD.
Effectiveness of a fully digital mandibular advancement appliance compared with CPAP in the treatment of obstructive sleep apnea.
This crossover clinical study compared a fully digital mandibular advancement appliance (MAA) with CPAP in 20 adults with obstructive sleep apnea (OSA), confirmed by polysomnography and non-adherent to CPAP.
Brought with the wind: A case of melioidosis acquired in the United States presenting with multiple pulmonary nodules.
A Florida resident without recent international travel presented with fever, pleuritic chest pain, and hypoxia after severe weather.
Effect of web-based education on NIV-related side effects and insomnia severity in COPD patients using home NIV: a randomized controlled trial.
This randomized controlled trial evaluated web-based education about NIV-related side effects and insomnia management in 75 patients with COPD using home noninvasive ventilation.
Lung ultrasound-guided protocolized fluid management versus conventional central venous pressure-based management in monitoring extravascular lung water during the perioperative period of percutaneous nephrolithotomy: a randomized controlled trial.
This randomized controlled trial compared lung ultrasound (LUS)-guided protocolized fluid management with conventional central venous pressure (CVP)-based management in 181 patients undergoing elective percutaneous…
Secondary pulmonary alveolar proteinosis mimicking progression of interstitial lung disease during treatment for adult-onset still's disease: An autopsy case report.
A 68-year-old woman with adult-onset Still’s disease-associated interstitial lung disease developed worsening respiratory failure while receiving immunosuppressive therapy, despite apparent control of systemic…
Kartagener syndrome with pulmonary mycetoma and recurrent thromboembolism: A case report.
A 27-year-old man with Kartagener syndrome and situs inversus totalis presented with worsening dyspnea, chest pain, fever, hemoptysis, and ankle swelling, against a history of deep vein thrombosis, recurrent pulmonary…
Emergency treatment of acute massive hemorrhage during transbronchial lung biopsy outside operating room: Case report.
A patient with pneumonia, emphysema, a pulmonary nodule, prior breast-cancer radiotherapy, coronary disease after PCI, severe hypertension, and atrial fibrillation developed massive bleeding during fiberoptic…
Measurement properties of pulmonary function measurement and patient-reported outcome measures in patients with multiple rib fracture without flail segment; validation study alongside the multicenter FixCon trial.
This multicenter validation study, conducted alongside a randomized controlled trial, assessed pulmonary function, pain, and health-related quality-of-life measures in 180 adults with multiple rib fractures without a…
Home-based, remotely supervised, high-intensity interval training and cardiorespiratory fitness in children and adolescents with post-infectious bronchiolitis obliterans: a randomised controlled trial.
This assessor-blinded, multicentre randomised controlled trial evaluated 16 weeks of home-based, real-time remotely supervised high-intensity interval training (HIIT) in children and adolescents aged 6–20 years with…
Effects of complementary therapies on physiological and psychological outcomes in chronic obstructive pulmonary disease patients: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled 36 randomized controlled trials involving 3148 people with COPD to assess complementary therapies, including exercise-based and psychological approaches.
Allergic bronchopulmonary mycosis associated with Talaromyces boninensis: A case report.
A patient was evaluated for allergic bronchopulmonary mycosis (ABPM), an airway hypersensitivity disorder that can be caused by fungi other than Aspergillus.
Comparative effects of inspiratory and expiratory muscle training on diaphragm adaptations and respiratory function in adolescent athletes: a randomized-controlled study.
This randomized controlled study compared inspiratory muscle training (IMT) with expiratory muscle training (EMST) in 26 adolescent female volleyball players.
Manual compared to automated closed-loop oxygen control strategies in hospitalised adults: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomised controlled trials comparing closed-loop oxygen control (CLOC) with manual adjustment in hospitalised adults receiving noninvasive oxygen.
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