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1382 articles

November 20265

Case ReportPediatrics

Domino Liver Transplantation Using the Explanted Native Liver of a Multivisceral Transplant Recipient: A Pediatric Case Report and Systematic Review.

A 4-month-old boy underwent multivisceral transplantation after near-total enterectomy complicated by gastric, duodenal, and bladder fistulas.

Pediatr TransplantNov 1, 2026Read case
Clinical ResearchPediatrics

Prevalence and Geographic Distribution of Molar-Incisor Hypomineralisation in Spain: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed molar-incisor hypomineralisation (MIH) prevalence in Spanish children and adolescents aged 6–18 years.

Eur J Paediatr DentNov 1, 2026Read summary
Case ReportPediatrics

Preemptive Kidney Transplantation in a Pediatric Patient With Factor XI Deficiency: A Case Report.

A 14-year-old boy with end-stage renal disease from congenital posterior urethral valves underwent preemptive living-donor heterotopic kidney transplantation from his brother.

Pediatr TransplantNov 1, 2026Read case
Case ReportPediatrics

Pediatric Liver Transplantation Following Donation After Circulatory Death Using Normothermic Regional Perfusion: A Novel Application.

A 15-year-old girl with fulminant hepatic failure after acetaminophen overdose underwent liver transplantation using a donation-after-circulatory-death graft recovered with thoracoabdominal normothermic regional…

Pediatr TransplantNov 1, 2026Read case
Clinical ResearchPediatrics

Diagnosis and Management of Achalasia in Children, BSPGHAN and BAPS Consensus Statement.

This consensus statement addresses diagnosis and management of achalasia in children, for whom pediatric-specific guidelines were lacking.

Neurogastroenterol MotilNov 1, 2026Read summary

October 202619

Clinical ResearchNeurologyOpen access

Pharmacological Interventions for Neurological Manifestations of Ataxia-Telangiectasia: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials.

This updated systematic review and meta-analysis examined randomized trials of pharmacological treatments for neurological manifestations of ataxia-telangiectasia in children and adults.

CerebellumOct 31, 2026Read summary
Case ReportPediatricsOpen access

Solitary Neurofibroma in the Submental Region of a 15-Year-Old Adolescent: A Case Report and Review of Literature.

A 15-year-old boy had a painless right submental swelling present for one year, with enlargement over the preceding three months.

Int Med Case Rep JOct 31, 2026Read case
Clinical ResearchOtolaryngology (ENT)

Postural control differences in children who are deaf or hard of hearing: A systematic review and meta-analysis of postural sway outcomes.

This systematic review and meta-analysis examined static posturography findings in children who are deaf or hard of hearing (DHH), compared with typically hearing peers.

Gait PostureOct 31, 2026Read summary
Case ReportMedical Genetics

Prenatal Microarray Incidentally Diagnoses a Novel Inherited NF1 Intragenic Duplication.

A woman with an undisclosed clinical diagnosis of NF1, lost to follow-up as a teenager, received a molecular diagnosis after prenatal chromosome microarray was performed because first-trimester screening indicated a…

Mol Genet Genomic MedOct 30, 2026Read case
Clinical ResearchPediatrics

Effectiveness of Tomazoni Measurement Method for Central Catheter Tip Positioning in Neonates: A Randomised Controlled Trial.

This pragmatic, parallel-group randomised controlled trial compared the Tomazoni and traditional measurement methods for positioning peripherally inserted central catheter (PICC) tips in neonates at a Brazilian neonatal…

Nurs Crit CareOct 30, 2026Read summary
Clinical ResearchPediatrics

Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial.

PROSpect was an international, two-by-two factorial, phase 3 randomised controlled trial comparing prone with supine positioning and high-frequency oscillatory ventilation (HFOV) with conventional mechanical ventilation…

LancetOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Second-hand smoke exposure linked to TB infection or disease in children/adolescents: systematic review and meta-analysis.

This PROSPERO-registered systematic review and meta-analysis examined observational evidence on household second-hand smoke (SHS) exposure and tuberculosis (TB) outcomes in children and adolescents aged 0–18 years in…

Int J Tuberc Lung DisOct 30, 2026Read summary
Clinical ResearchPediatrics

Effects of Parent-Involved Digital Health Interventions on Adiposity-Related Outcomes and Behaviors in Children and Adolescents With Overweight or Obesity: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined randomized controlled trials of parent-involved digital health interventions for children and adolescents with overweight or obesity.

J Med Internet ResOct 30, 2026Read summary
Clinical ResearchPediatricsOpen access

Nurse-Led treatment strategy based on asthma score and oxygen requirement in children with acute reversible bronchoconstriction: A randomised controlled non-inferiority trial.

This multicentre, open-label, randomised non-inferiority trial compared nurse-led treatment guided by the oxygen-adjusted Childhood Asthma Score (CAS O2) with the standard CAS protocol in children aged 2–18 years…

PLoS OneOct 30, 2026Read summary
Clinical ResearchPediatricsOpen access

Space changes after premature loss of mandibular second primary molars: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed space changes after premature extraction of mandibular second primary molars in children aged 4–9 years.

BMC Oral HealthOct 30, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

Effect of Intravenous Acetaminophen on Preemptive Multimodal Analgesia for Pediatric Osteotomy Correction Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

Children undergoing Osteotomy correction surgery can experience substantial postoperative pain and frequently require opioids.

Drug Des Devel TherOct 30, 2026Read case
Case ReportPediatricsOpen access

Delayed Presentation of Neonatal Omphalitis with Suspected Invasive Soft-Tissue Infection and Late-Onset Sepsis Following Non-Sterile Home Delivery: A Case Report.

A 19-day-old girl presented with fever, poor feeding, abdominal distension, purulent umbilical discharge, periumbilical inflammation and necrotic-appearing tissue after a non-sterile home delivery and cord tying with…

Int Med Case Rep JOct 30, 2026Read case
Clinical ResearchPediatrics

Effects of a Multicomponent App-Based Exercise Program on Motor Skill Development in Children With Attention Deficit Hyperactivity Disorder: A Secondary Outcome Analysis of a Three-Arm Randomized Controlled Trial.

This secondary outcome analysis of a three-arm randomized controlled trial assessed motor skills in 145 children aged 6–10 years with ADHD.

Scand J Med Sci SportsOct 29, 2026Read summary
Case ReportMedical Genetics

PIH1D2 Loss-of-Function Directs Ciliary and Cell Cycle Defects Resulting in Left Isomerism With or Without Biliary Atresia.

Two unrelated patients with left isomerism heterotaxy were found by genome sequencing to have biallelic loss-of-function variants in PIH1D2.

Liver IntOct 29, 2026Read case
Clinical ResearchOphthalmology

Evaluation of digital binocular therapies for amblyopia after refractive adaptation in treatment-naive children aged 3-13 years: A systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis of randomised controlled trials assessed digital binocular therapies versus patching for visual acuity improvement in treatment-naive children aged 3–13 years with unilateral…

PLoS OneOct 29, 2026Read summary
Clinical ResearchPediatrics

Effect of nutrition counseling on complementary feeding practices among mothers with children aged 6-23 months in West Gojjam Zone, Northwest Ethiopia: A cluster-randomized controlled trial.

This two-arm, parallel cluster-randomized controlled trial assessed Health Belief Model-based nutrition counseling for mothers of children aged 6–23 months in rural West Gojjam Zone, Northwest Ethiopia.

PLoS OneOct 29, 2026Read summary
Case ReportMedical GeneticsOpen access

Expanding the molecular and phenotypic spectrum of MMP2-related multicentric osteolysis, nodulosis, and arthropathy: two brothers with marked intrafamilial variability and a review of the literature.

Two brothers, aged 14 and 8 years, from a consanguineous family had molecularly confirmed MMP2-related multicentric osteolysis, nodulosis, and arthropathy (MONA), with the same homozygous c.1648 C > T (p.Arg550Ter)…

Mol Biol RepOct 29, 2026Read case
Clinical ResearchPediatricsOpen access

Timing of intratracheal administration of budesonide mixed with surfactant to prevent bronchopulmonary dysplasia: a systematic review and meta-analysis.

This systematic review and meta-analysis examined randomised trials comparing intratracheal budesonide mixed with surfactant against surfactant alone in infants, assessing bronchopulmonary dysplasia (BPD) and whether…

Eur J PediatrOct 29, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Infantile posterior fossa atypical teratoid/rhabdoid tumor: navigating diagnostic complexity and molecular paradigms.

A female infant younger than 1 year presented with a massive cystic-solid posterior fossa tumor and rapidly developing obstructive hydrocephalus.

Childs Nerv SystOct 29, 2026Read case

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