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495 articles

October 202623

Case ReportOphthalmologyOpen access

Extensive recurrent pterygium following photorefractive keratectomy: a case report.

A healthy 39-year-old man developed an extensive recurrent pterygium three months after uneventful photorefractive keratectomy (PRK), having undergone primary pterygium surgery two months before PRK.

BMC OphthalmolOct 13, 2026Read case
Case ReportOphthalmology

Extracting the Unexpected: A 35-mm Curved Nail as an Intraocular Foreign Body.

A 31-year-old man presented with left-eye pain and severe vision loss seven days after penetrating injury from a metallic object.

Am J Case RepOct 12, 2026Read case
Clinical ResearchOphthalmologyOpen access

Oral eplerenone in first-episode acute central serous chorioretinopathy: results of a double-masked randomized trial.

This double-masked, randomized, placebo-controlled trial evaluated oral eplerenone in 44 patients with first-episode acute central serous chorioretinopathy (CSCR).

Int OphthalmolOct 12, 2026Read summary
Case ReportOphthalmologyOpen access

Pediatric conjunctival papilloma managed with staged multimodal therapy: a case report.

A 4-year-old boy presented with multifocal conjunctival papillomatous lesions and was diagnosed with conjunctival papilloma. Topical and intralesional interferon alfa-2b were used before surgery to reduce lesion size.

BMC OphthalmolOct 11, 2026Read case
Case ReportMedical GeneticsOpen access

Intrafamilial phenotypic variation in four Palestinian siblings with CFAP418-related ciliopathy: a familial case series.

Four Palestinian siblings from a consanguineous family were homozygous for the CFAP418 splice-donor variant NM_177965.3:c.155 + 1G > A.

BMC OphthalmolOct 11, 2026Read case
Clinical ResearchOphthalmology

Preclinical and clinical evaluation of an ocular nanoemulsion for the treatment of dry eye disease.

This study evaluated a preservative-free castor oil and sodium hyaluronate nanoemulsion (VSLB) for dry eye disease in a scopolamine-induced rat model and a prospective, randomized, double-masked clinical study of 64…

Expert Opin Drug DelivOct 10, 2026Read summary
Clinical ResearchOphthalmology

Dexamethasone versus triamcinolone acetonide for the management of postoperative inflammation following cataract surgery: A systematic review and meta-analysis.

This systematic review and meta-analysis compared dexamethasone with triamcinolone acetonide (TCA) for postoperative inflammation in adults undergoing phacoemulsification.

Medicine (Baltimore)Oct 9, 2026Read summary
Case ReportOphthalmology

Outcomes of sequential keratoplasty for bilateral gelatinous drop-like corneal dystrophy: A case report.

A 21-year-old woman of Yemeni ancestry with long-standing bilateral visual impairment, progressive left-eye decline, foreign-body sensation, and a positive family history had previously undergone right penetrating…

Medicine (Baltimore)Oct 9, 2026Read case
Clinical ResearchOphthalmology

Optogenetic Therapy for Restoring Aspects of Visual Function.

This open-label clinical trial evaluated safety and visual-function outcomes after ganglion cell-directed optogenetic therapy in 10 participants with blindness from advanced retinitis pigmentosa.

N Engl J MedOct 8, 2026Read summary
Case ReportOphthalmologyOpen access

Trigeminal sensory neuropathy developing as a late complication after the treatment of surgically induced necrotizing scleritis following pterygium surgery: a case report and literature review.

A 31-year-old woman developed right-eye irritation, reduced vision, and photophobia after bilateral pterygium surgery. Examination showed melting of the conjunctival autograft with exposed sclera and a visible choroidal…

BMC OphthalmolOct 8, 2026Read case
Case ReportOphthalmology

Time to improve laboratory protocols in microbial keratitis: broad-range Internal Transcribed Spacer sequencing in refractory culture-negative keratitis.

A woman in her 60s who wore soft contact lenses developed rapidly progressive microbial keratitis that did not respond to intensive empirical treatment.

BMJ Case RepOct 7, 2026Read case
Case ReportOphthalmology

Acute retinal necrosis refractory to treatment.

A woman in her 60s presented with hypertensive uveitis in the right eye, followed by vitritis and retinitis. An anterior chamber sample was positive for herpes simplex virus by PCR.

BMJ Case RepOct 7, 2026Read case
Case ReportOncology (Medical)

Scleral perforation in a young adult with Burkitt lymphoma.

A man in his 20s with Burkitt lymphoma receiving chemotherapy was referred for lagophthalmos and left facial nerve palsy. Weeks later, he developed acute scleral perforation.

BMJ Case RepOct 7, 2026Read case
Case ReportOphthalmology

Eosinophilic angiocentric fibrosis in paediatric IgG4-related disease.

A young girl presented with a 1.5-year history of progressive bilateral upper eyelid swelling and proptosis, more pronounced on the right.

BMJ Case RepOct 6, 2026Read case
Case ReportRheumatologyOpen access

Abatacept in biologic-refractory juvenile idiopathic arthritis-associated uveitis: a case-based review.

Monoclonal anti-tumor necrosis factor (anti-TNF) agents have substantially improved the management of juvenile idiopathic arthritis (JIA)-associated uveitis.

Clin RheumatolOct 6, 2026Read case
Case ReportOphthalmology

Uveitis despite adalimumab therapy in Blau syndrome.

A middle childhood boy initially diagnosed with oligoarticular juvenile idiopathic arthritis presented with persistent arthritis, recurrent fever, and skin lesions.

BMJ Case RepOct 5, 2026Read case
Clinical ResearchOphthalmology

Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.

This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.

Transl Vis Sci TechnolOct 5, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

Genotype-Phenotype Relationships in Patients Carrying Biallelic FDXR Pathogenic Variants-New Cases and Systematic Review.

Biallelic pathogenic FDXR variations were identified in 2017 as being responsible for sensorial neuropathies. The first reported patients suffered from auditory and optic sensorineural impairments (ANOA, MIM #617717).

Hum MutatOct 2, 2026Read summary
Case ReportOncology (Medical)

Presentation and management of tislelizumab induced toxic optic neuropathy.

A woman with metastatic lung adenocarcinoma developed painless, progressive bilateral visual blurring after receiving second-line treatment with gemcitabine, carboplatin, and tislelizumab.

BMJ Case RepOct 1, 2026Read case
Case ReportDermatology

Cicatricial Ectropion in the Setting of IL-13 Inhibition.

An 81-year-old man with extensive atopic dermatitis was treated with dupilumab, leading to significant improvement. However, he later developed ocular symptoms and inferior cicatricial ectropion of the left lower eyelid.

J Drugs DermatolOct 1, 2026Read case
Case ReportOphthalmology

Identification of Variants in Two Families With Congenital Cataract by Whole Exome Sequencing.

Congenital cataract (CC) is an ophthalmic disorder diagnosed at birth or during early infancy, characterized by severe visual impairment and potential blindness.

Mol Genet Genomic MedOct 1, 2026Read case
Case ReportOphthalmology

Anterior Stromal Melt Following Implantation of a Large Size Corneal Allogenic Intrastromal Ring Segment (CAIRS).

To report delayed anterior stromal melt following corneal allogenic intrastromal ring segment (CAIRS) implantation in a patient without known systemic or ocular risk factors.

J Refract SurgOct 1, 2026Read case
Case ReportOphthalmology

Sutureless Epikeratophakia After Small Incision Lenticule Extraction: A Case Report to Correct Corneal Deformity.

An 18-year-old woman developed severe corneal thinning, with a residual stromal bed of 176 μm, and irregular hyperopic astigmatism in her left eye after a femtosecond laser malfunction during keratorefractive lenticule…

J Refract SurgOct 1, 2026Read case

September 20261

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