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1240 articles
October 202624
Catheter ablation in end-stage heart failure with atrial fibrillation: an hierarchical endpoint analysis of the CASTLE-HTx trial.
This ancillary hierarchical endpoint analysis of the multicentre randomized CASTLE-HTx trial compared catheter ablation plus guideline-directed medical therapy (GDMT) with medical therapy alone in 194 patients with…
A NETwork meta-analysis with COST-effectiveness evaluation of pharmacological treatments for heart failure with reduced ejection fraction: NET-COST-HFrEF.
This network meta-analysis of 47 randomized controlled trials involving 75,978 patients with heart failure with reduced ejection fraction assessed guideline-directed drug combinations and their cost-effectiveness.
Performance of prediction models for incident heart failure and heart failure hospitalization in individuals with type 2 diabetes: a systematic review and meta-analysis.
This systematic review and Bayesian meta-analysis assessed multivariable models predicting incident heart failure (HF) or HF hospitalization (HFH) in people with type 2 diabetes.
Effect of vutrisiran on components of health status in transthyretin amyloidosis with cardiomyopathy: the HELIOS-B study.
This analysis of HELIOS-B, a double-blind, randomized, placebo-controlled trial, examined individual health-status components in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).
Impact of acoramidis on clinical stability in transthyretin amyloid cardiomyopathy: observations from ATTRibute-CM.
This post-hoc analysis of the phase 3, multicentre, randomised ATTRibute-CM trial assessed clinically meaningful changes in NT-proBNP or 6-minute walk distance among participants with transthyretin amyloid…
Mitral regurgitation in patients with heart failure and reduced ejection fraction: insights from GALACTIC-HF.
This analysis of the randomized, multicentre GALACTIC-HF trial examined mitral regurgitation (MR) and outcomes in patients with heart failure and reduced ejection fraction.
Acute pericarditis caused by Kocuria kristinae with successful withdrawal from hemodialysis: a case report.
A 47-year-old man developed dialysis-dependent acute kidney injury after severe heatstroke. About a month later, imaging showed a marked increase in cardiothoracic ratio, and echocardiography demonstrated a substantial…
Efficacy and safety of intralesional versus intracoronary administration of glycoprotein IIb/IIIa inhibitors during percutaneous coronary intervention for acute coronary syndromes: a meta-analysis of randomized controlled trials.
This meta-analysis of nine randomized controlled trials compared intralesional with intracoronary glycoprotein IIb/IIIa inhibitor administration during PCI in patients with acute coronary syndromes.
Four weeks of isometric handgrip training results in lower awake ambulatory blood pressure compared with control: a randomized clinical trial.
This randomized controlled trial compared handgrip and knee-extension isometric training with control in 67 adults with controlled hypertension receiving antihypertensive medication.
Effectiveness of Wrist-Worn Wearable-Guided Cardiac Rehabilitation Delivered Through Fully Remote or Hybrid Programs in Patients With Cardiovascular Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis assessed randomized trials of wrist-worn wearable-guided cardiac rehabilitation delivered remotely or in hybrid formats during phase II or III rehabilitation for adults with…
Isolated Disturbance of Consciousness as Initial Presentation of Staphylococcus aureus Endocarditis: A Case Report With Brief Literature Review.
A man in his 50s presented with isolated disturbance of consciousness and no reported fever, although his admission temperature was 38°C.
Diagnostic accuracy of high-sensitivity point-of-care troponin assays in emergency department for patients presenting with chest pain: a systematic review.
This systematic review assessed the diagnostic accuracy of four commercially available high-sensitivity point-of-care troponin assays in adults presenting to emergency departments with chest pain suggestive of acute…
Effect of Preoperative Intranasal Dexmedetomidine on Postoperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting.
To evaluate the effects of preoperative intranasal dexmedetomidine on postoperative myocardial injury biomarkers in patients undergoing on-pump coronary artery bypass grafting (CABG).
Safety of low lipoprotein(a) levels: the FOURIER trial.
This analysis of the randomized, multicentre FOURIER trial examined associations between lipoprotein(a) [Lp(a)] levels and safety outcomes in patients with stable atherosclerotic cardiovascular disease receiving…
Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome.
This post hoc prognostic analysis of the multicentre ODYSSEY OUTCOMES randomised trial examined hsCRP and IL-6 in 11,817 patients with recent acute coronary syndrome.
Safety and Effectiveness of a Novel Laser-Based Intravascular Lithotripsy System for Coronary Calcium: FRACTURE Study.
FRACTURE was a prospective, multicenter, single-arm clinical trial evaluating a laser- and optic-based quad-emitter intravascular lithotripsy system in patients with severely calcified de novo coronary lesions.
The association between e-cigarette use and dyslipidemia: A systematic review and meta-analysis of observational studies.
This systematic review and meta-analysis examined observational evidence on exclusive e-cigarette use and blood lipids in adults. Seven studies from four countries included 25,690 participants.
Intracardiac thrombus and multiple venous thromboses revealing focal segmental glomerulosclerosis.
A 51-year-old woman presented with two weeks of lower-limb edema and hematuria. Imaging showed lower-extremity deep vein thrombosis, partial left renal vein thrombosis, and a 23 × 20 mm left ventricular thrombus.
Individual Effects of Angiotensin II Receptor Blockers on Major Adverse Cardiovascular Events: A Systematic Review and Network Meta-Analysis.
This systematic review and random-effects network meta-analysis compared angiotensin II receptor blockers (ARBs) for cardiovascular outcomes in randomized trials not primarily designed to study heart failure.
Effectiveness of Implantable Cardioverter-Defibrillator Therapy for Primary Prevention in Patients with Nonischemic Heart Failure with Reduced Ejection Fraction.
This rapid systematic review and meta-analysis assessed primary-prevention implantable cardioverter-defibrillator (ICD) therapy in patients with nonischemic heart failure with reduced ejection fraction, drawing on 18…
A randomized study comparing plant sterol- and soluble fiber-enriched soymilk with plain soymilk in adults with elevated LDL cholesterol.
This randomized controlled trial compared plant sterol- and soluble fiber-enriched soymilk with plain soymilk in 242 adults with hypercholesterolemia, untreated or on stable lipid-lowering therapy.
Tricuspid Chordae Tendineae Rupture Detected After Repair of a Delayed Traumatic Left Ventricular Aneurysm: A Case Report.
After a fall from a height, a patient presented 54 days later with rupture of a posterior left ventricular aneurysm. Venoarterial extracorporeal membrane oxygenation provided circulatory support before surgical aneurysm…
Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.
This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…
Role of Plasma Proteins in the Association Between Socioeconomic Status and Cardiovascular Disease Events: Results From Trans-Omics for Precision Medicine Cohorts.
This meta-analysis examined socioeconomic status (SES), plasma proteins, and incident coronary heart disease (CHD) and stroke in participants from three cohorts.
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