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2000 articles
September 202624
Cardiovascular disease and amyloidosis in phase III multiple myeloma trials: a systematic review of eligibility, screening and event reporting.
This systematic review evaluated phase III randomized controlled trials of multiple myeloma therapies, focusing on eligibility criteria related to cardiovascular disease (CVD) and amyloidosis.
Meningioma regression following discontinuation of depot medroxyprogesterone acetate.
Three patients with meningioma who were under active surveillance experienced tumor regression after discontinuing depot medroxyprogesterone acetate (dMPA).
The role of stereotactic radiosurgery for prostate cancer spine metastasis - impact on hormone sensitivity and treatment outcomes: a systematic review of literature.
This systematic review evaluated the outcomes of stereotactic body radiotherapy (SBRT) for spinal metastases in prostate cancer, focusing on hormone-sensitive (HSPC) versus castration-resistant (CRPC) disease.
TQB2618 plus Penpulimab, Alone or in Combination with Chemotherapy, for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Multicenter, Two-Cohort, Phase II Trial.
This Phase II multicenter trial evaluated the efficacy and safety of TQB2618 plus penpulimab in recurrent/metastatic nasopharyngeal carcinoma.
A Phase I and Biodistribution Study of Ifabotuzumab, a Humanized Agonistic EphA3-Targeted Antibody, in Patients with Recurrent Glioblastoma.
This Phase I multicenter study evaluated the safety and biodistribution of ifabotuzumab, an EphA3-targeted antibody, in 12 adults with recurrent glioblastoma.
Anterior Cutaneous Nerve Entrapment Syndrome in a 51-Year-Old Woman With Advanced Colon Cancer, Successfully Treated With Repeated Ultrasound-Guided Rectus Sheath Blocks: A Case Report.
A 51-year-old woman with advanced sigmoid colon cancer presented with severe movement-related abdominal pain unresponsive to high-dose opioids.
A Phase Ib/IIa Study of Fostrox in Combination with Lenvatinib as Second-line Therapy in Patients with Advanced Hepatocellular Carcinoma.
This multicenter, single-arm Phase Ib/IIa study evaluated the combination of fostroxacitabine bralpamide (fostrox) and lenvatinib in 21 patients with advanced hepatocellular carcinoma (HCC) who progressed on prior…
A Case of Concurrent Liver Metastases from Colorectal and Breast Cancer Diagnosed Using Percutaneous Tumor Biopsy.
A 71-year-old woman with metastatic lobular breast carcinoma developed new liver lesions after initial treatment. Imaging revealed multiple bilobar liver tumors with distinct patterns, prompting further investigation.
Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy.
This Phase I trial evaluated the safety and efficacy of intravenous VCN-01 oncolytic adenovirus combined with durvalumab in patients with recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) refractory to…
Malignant MITF-Rearranged PEComa With Novel EEF1A1::MITF Fusion.
A 45-year-old woman presented with a malignant superficial soft tissue neoplasm in the thigh, characterized by epithelioid to plump spindle cells with significant cytologic atypia and brisk mitotic activity.
Acceptability, perceived outcomes and underlying mechanisms of a professionally led support group intervention for women with breast cancer using a qualitative method approach.
This qualitative study evaluated the acceptability and perceived impact of the Mind Support Group (MSG) intervention for 22 women with breast cancer (stages I-III).
Intravesical mitomycin-C administered immediately before transurethral resection of bladder tumor in non-muscle-invasive bladder cancer: Clinical outcomes and molecular predictors from over 3 years of extended follow-up in a phase II trial.
This phase II randomized controlled trial evaluated the long-term outcomes of immediate preoperative intravesical chemotherapy with mitomycin-C (MMC) in 71 patients with non-muscle-invasive bladder cancer (NMIBC).
KangDuo surgical robot KD-SR-01 versus da Vinci Xi in robot-assisted colorectal cancer resection: oncologic outcomes at three years in a multicenter randomized trial.
This multicenter randomized trial compared the long-term oncologic outcomes of the KangDuo surgical robot KD-SR-01 and the da Vinci Xi in 100 patients undergoing colorectal cancer resection.
CD19 CAR T-cell therapy (GLPG5101) for relapsed or refractory B-cell non-Hodgkin lymphoma (ATALANTA-1): phase 1 results from a single-arm, multicentre, phase 1/2 study.
This phase 1/2 study evaluated the safety of GLPG5101, a fresh CD19 CAR T-cell therapy, in 24 patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
A Meta-Analysis of the Impact of Lifestyle and Gynecologic Oncology Nursing Interventions on the Enhancement of Quality of Life.
This meta-analysis assessed the effects of lifestyle and gynecologic oncology nursing interventions on quality of life (QoL) in 915 women with gynecologic cancer across 13 randomized controlled trials.
Venetoclax added to dose-adjusted EPOCH-R for newly diagnosed double-hit lymphomas: phase 2 results from ALLIANCE A051701, an open-label, randomised, controlled, phase 2-3 trial.
This phase 2-3 randomized controlled trial evaluated the efficacy of adding venetoclax to dose-adjusted EPOCH-R in patients with newly diagnosed double-hit lymphoma. The study included 73 patients aged 18-80 years.
Epcoritamab with rituximab and lenalidomide as first-line treatment for follicular lymphoma (EPCORE NHL-2): an open-label, multicentre, phase 1/2 b trial.
This open-label, phase 1b/2 trial evaluated the efficacy and safety of epcoritamab combined with rituximab and lenalidomide as first-line treatment for follicular lymphoma in 41 eligible patients.
Phase Ib Trial of Bavdegalutamide (ARV-110) in Combination with Abiraterone for Metastatic Prostate Cancer.
This phase Ib trial assessed the safety and pharmacokinetics of bavdegalutamide combined with abiraterone in 45 patients with metastatic prostate cancer (mPC) experiencing PSA progression.
Targeting Fibroblast Activation Protein with [177Lu]Lu-FAP-2286 in Patients with Advanced Solid Tumors in the Phase I LuMIERE Trial.
The Phase I LuMIERE trial evaluated the safety of [177Lu]Lu-FAP-2286 in 27 heavily pretreated patients with advanced solid tumors.
Network meta-analysis of bisphosphonates in the treatment of bone metastases from breast cancer.
This network meta-analysis evaluated the efficacy and safety of bisphosphonates in reducing skeletal-related events in 14,934 patients with bone metastases from breast cancer.
Angiosarcoma Presenting as a Chronic Non-Healing Lower Extremity Ulcer in Lymphoedema: A Challenge.
A 74-year-old woman with chronic lower extremity lymphoedema presented with a non-healing ulcer, initially treated as cellulitis and venous ulceration.
Enhancing Self Care Among Oral Cancer Survivors Using a Digital Approach: The Empowered Survivor Trial.
This randomized controlled trial evaluated the effectiveness of the Empowered Survivor (ES) digital intervention in enhancing self-efficacy and self-care among 643 oral and oropharyngeal cancer survivors.
Population Pharmacokinetics and Exposure-Response Analyses of Savolitinib Alone or in Combination With Osimertinib in Patients With Locally Advanced or Metastatic Solid Tumors.
This Phase II clinical trial analyzed the population pharmacokinetics of savolitinib in 998 patients with advanced solid tumors.
Sensitivity to Endocrine Therapy Index Predicts Benefit from Weekly Adjuvant Paclitaxel for Hormone Receptor-Positive Breast Cancer in the GEICAM/9906 Trial.
This randomized controlled trial evaluated the predictive value of the sensitivity to endocrine therapy (SETER/PR) index for the benefit of weekly adjuvant paclitaxel in hormone receptor-positive breast cancer.
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