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2000 articles

October 202624

Clinical ResearchNeurology

Is resistance training effective to increase BDNF in multiple sclerosis? An updated systematic review and meta-analysis of isolated interventions.

This systematic review and meta-analysis examined whether isolated resistance training (RT) affects peripheral brain-derived neurotrophic factor (BDNF) in people with multiple sclerosis (MS).

PLoS OneOct 27, 2026Read summary
Case ReportDermatology

Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.

A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.

Clin Exp DermatolOct 27, 2026Read case
Clinical ResearchPediatrics

Endobronchial Valves for Persistent Air Leak and Bronchopleural Fistula in Children: A Systematic Review of Indications, Procedural Approaches, and Outcomes.

This systematic review examined bronchoscopic endobronchial or intrabronchial valve placement for persistent air leak, bronchopleural fistula, or pneumothorax with ongoing air leak in children and late adolescents.

J Bronchology Interv PulmonolOct 27, 2026Read summary
Case ReportDermatology

Cutaneous features of SDR9C7 variants in eight individuals with autosomal recessive nonsyndromic epidermal differentiation disorders.

Eight individuals with SDR9C7 variants and nonsyndromic epidermal differentiation disorders had scaling and erythema, commonly with fine scale, hyperlinear palms, and greater involvement of the extremities, particularly…

Clin Exp DermatolOct 27, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Intrauterine Mepivacaine Instillation vs Placebo for Pain During IUD Placement: A Randomized Clinical Trial.

This multicentre, double-blind, randomised, placebo-controlled trial tested intrauterine mepivacaine before IUD placement in nulliparous individuals aged 18 to 31 years at 11 Swedish clinics.

JAMAOct 27, 2026Read summary
Case ReportPulmonology

Two Older Adult Patients With Anorexia and Cachexia Following Refractory Mycobacterium avium-intracellulare Complex Pulmonary Disease Given Acupuncture Treatment to Improve Appetite and Food Intake.

Two older adults with refractory cavitary Mycobacterium avium-intracellulare complex pulmonary disease developed severe anorexia, dyspnea associated with eating, and cachexia.

Am J Case RepOct 27, 2026Read case
Clinical ResearchObstetrics & Gynecology

Effectiveness of theory-based educational interventions on fertility and childbearing intentions: a systematic review and meta-analysis among Iranian populations.

This systematic review and meta-analysis assessed theory-based educational interventions and fertility or childbearing intentions among Iranian populations.

Hum Fertil (Camb)Oct 27, 2026Read summary
Clinical ResearchPsychiatry

Purrble Use Among LGBTQ+ Young People With Self-Harm Experiences: Findings From a Qualitative Process Evaluation of a Randomized Controlled Trial.

This qualitative process evaluation explored how LGBTQ+ young people with self-harm experiences used and perceived Purrble, a socially assistive robot evaluated in a related randomized controlled trial.

JMIR Form ResOct 27, 2026Read summary
Case ReportPhysical Medicine & Rehabilitation

Ultrasound-Guided High-Voltage Long-Duration Pulsed Radiofrequency of the Suprascapular Nerve for Persistent Hemiplegic Shoulder Pain.

The report describes two patients with persistent hemiplegic shoulder pain after stroke, in whom conventional conservative care or suprascapular nerve blocks may provide inadequate relief.

J Vis ExpOct 27, 2026Read case
Clinical ResearchPsychiatry

Combining Cognitive Training and Brain Stimulation: A Novel Approach to Address Disordered Eating and Antipsychotic-Induced Weight Gain in People With Severe Mental Illness.

This double-blind, parallel-group, sham-controlled randomised trial assessed the feasibility of combining Approach Bias Modification Training (ABMT) with real or sham transcranial direct current stimulation (tDCS) in…

Early Interv PsychiatryOct 27, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Three-week ileostomy closure after colorectal surgery: a multicenter randomized trial of technical and postoperative outcomes.

This prospective multicenter randomized trial compared ileostomy closure at 3 weeks with conventional delayed closure in 224 patients after restorative colorectal resection.

Tech ColoproctolOct 27, 2026Read summary
Case ReportAllergy & Immunology

Disruption of the N-terminal domain in a STAT3 hyper-IgE syndrome variant causes disease by sequestering STAT3 in the cytoplasm.

A patient with a STAT3 R31Q variant presented with disseminated invasive aspergillosis involving the brain and lung, bronchiectasis, and elevated serum IgE, without nonimmune manifestations of hyper-IgE syndrome.

Sci SignalOct 27, 2026Read case
Clinical ResearchUrologyOpen access

Robot-assisted versus open partial nephrectomy in patients with a solitary kidney: a systematic review and meta-analysis of perioperative and functional outcomes.

This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with open partial nephrectomy (OPN) for tumors in a solitary kidney.

J Robot SurgOct 27, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Virtual reality surgical simulator training of residents and early-career surgeons for pedicle screw placement: a systematic review and meta-analysis.

This systematic review and meta-analysis included six randomized controlled trials comparing virtual reality (VR) simulation with conventional teaching for pedicle screw placement training in residents and early-career…

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchVascular SurgeryOpen access

Revascularization of Asymptomatic Carotid Artery Stenosis: Cognitive Results of the CREST-2 Randomized Trials.

This prespecified cognitive-outcomes analysis of the multicentre, randomised CREST-2 trials assessed patients aged 35 years or older with at least 70% asymptomatic carotid stenosis.

JAMAOct 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Body image distress in women and men with advanced pancreatic cancer approaching death - post-hoc analyses from the MISTRAL-trial.

This post-hoc analysis of data from the MISTRAL trial examined changes in body image distress and weight worries among 125 women and men with pancreatic cancer during the six months before death.

Support Care CancerOct 27, 2026Read summary
Clinical ResearchInfectious Diseases

Hemagglutinin- and neuraminidase-targeting antibody responses after receipt of egg-based inactivated or recombinant influenza vaccines among adults aged 18-64 years.

This randomized trial compared hemagglutinin (HA)- and neuraminidase (NA)-targeting antibody responses after 2022–2023 recombinant influenza vaccine (RIV) or standard-dose inactivated influenza vaccine (SD-IIV) in…

VaccineOct 27, 2026Read summary
Clinical ResearchOrthopedic Surgery

Comparative effectiveness of three splints for rehabilitation after finger flexor tendon repair (FIRST): randomised controlled trial.

The FIRST pragmatic, multicentre randomised trial compared forearm-based long, Manchester short, and relative motion flexion mini splints for rehabilitation after primary zone 1 or 2 finger flexor tendon repair.

BMJOct 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Safety and efficacy of dual immune checkpoint inhibition for melanoma brain metastases and its comparison to ICI monotherapy: A systematic review and meta-analysis.

This PRISMA-based systematic review and meta-analysis pooled prospective and retrospective studies of adults with cutaneous or mucosal melanoma brain metastases treated with dual immune checkpoint inhibition (ICI), and…

Neurosurg RevOct 27, 2026Read summary
Clinical ResearchOncology (Medical)

Antibiotics and outcomes of cancer immunotherapy: An updated meta-analysis and clinical applications.

This updated meta-analysis examined antibiotic exposure and outcomes among 97,850 patients with cancer treated with immune checkpoint inhibitors (ICI), drawing on 116 cohorts.

Cancer CellOct 27, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Closed percutaneous reduction versus mini-open sinus tarsi approach for fixation of displaced intra-articular calcaneal fractures: a systematic review and meta-analysis.

This systematic review and meta-analysis compared closed percutaneous reduction (PR) with the mini-open sinus tarsi approach (STA) for acute displaced intra-articular calcaneal fractures.

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchGeneral Surgery

Associating liver partition and portal vein ligation for staged hepatectomy procedure versus conventional two-stage hepatectomy for colorectal liver metastasis.

This Cochrane systematic review and meta-analysis assessed ALPPS versus conventional two-stage hepatectomy in adults with colorectal liver metastases and an estimated future liver remnant below 30% of total liver…

Cochrane Database Syst RevOct 27, 2026Read summary
Case ReportGastroenterologyOpen access

Protein-losing enteropathy as a rare presentation of small bowel T-cell post-transplant lymphoproliferative disease.

A kidney transplant recipient developed episodic diarrhea, with initial investigations showing no bowel pathology. She later developed fluid retention associated with hypoalbuminemia, and technetium-99m human serum…

CEN Case RepOct 27, 2026Read case
Clinical ResearchPediatrics

Air versus supplemental oxygen for resuscitation of term or late preterm infants at birth.

This Cochrane systematic review and meta-analysis assessed randomised and quasi-randomised trials comparing air with supplemental oxygen for resuscitation at birth in term and late preterm infants needing respiratory…

Cochrane Database Syst RevOct 27, 2026Read summary

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