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1357 articles

October 202624

Clinical ResearchEndocrinology

Relationship between Vitamin D Status and the Risk of Obesity without Diagnosed Metabolic Syndrome: A Meta-Analysis of Observational Studies.

This systematic review and meta-analysis pooled observational studies examining vitamin D status and obesity without diagnosed metabolic syndrome.

J Obes Metab SyndrOct 19, 2026Read summary
Clinical ResearchCardiology

Cardiac Effects of Combined Versus Individual Interventions of Mediterranean Diet and Exercise in Adults with the Hypertriglyceridemic Waist Phenotype: A Randomized Trial.

This randomized 2 × 2 factorial trial assessed whether a Mediterranean diet and structured exercise, alone or combined, affected echocardiographic left ventricular (LV) structure and function in adults with the…

Metab Syndr Relat DisordOct 19, 2026Read summary
Clinical ResearchEmergency Medicine

POCUS Image Archiving in Emergency Medicine: A Systematic Review of Clinical and Financial Impacts.

This systematic review assessed clinical, operational, and financial outcomes of archiving point-of-care ultrasound (POCUS) images in electronic health records in emergency departments.

Ultrasound QOct 19, 2026Read summary
Clinical ResearchDermatology

Long-term efficacy of lebrikizumab in treating head, neck and face involvement in patients with moderate-to-severe atopic dermatitis.

This post hoc analysis of phase III trials assessed head, neck, and face (HNF) outcomes with lebrikizumab in adolescents and adults with moderate-to-severe atopic dermatitis.

J Dermatolog TreatOct 19, 2026Read summary
Clinical ResearchNeurologyOpen access

Magnetic resonance imaging vs computed tomography for baseline imaging evaluation in acute basilar artery occlusion.

This post hoc analysis of the ATTENTION trial compared baseline MRI with CT for patient selection in acute basilar-artery occlusion.

J NeurolOct 18, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Full-spectrum LED screen-bar lighting as an adjunct to artificial tears in visual display terminal-related dry eye: a randomized study.

This prospective, randomised, single-centre study assessed whether full-spectrum screen-bar lighting adds benefit to artificial tears in 66 participants with newly diagnosed visual display terminal-related dry eye and…

Int OphthalmolOct 18, 2026Read summary
Clinical ResearchAnesthesiology

The Impact of Anaesthesia Method on the Use of Anaesthesia Department Resources in Total Knee Arthroplasty.

This randomised controlled trial compared spinal anaesthesia with general anaesthesia using total intravenous anaesthesia in 395 patients undergoing total knee arthroplasty.

Acta Anaesthesiol ScandOct 18, 2026Read summary
Clinical ResearchGastroenterology

Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects.

This open-label, randomized, single-dose, three-period crossover study compared the pharmacokinetics and safety of 20 mg zastaprazan orally disintegrating tablets (ODTs), taken with or without water, with the…

Pharmacol Res PerspectOct 18, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Advances in physiotherapy for chronic low-back pain: a level I systematic review.

This level I systematic review qualitatively examined randomised controlled trials of physiotherapy programmes for chronic low-back pain (cLBP), identified through searches of PubMed, Web of Science and Embase in August…

J Orthop TraumatolOct 18, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Microsurgical clipping versus Woven EndoBridge embolization for intracranial aneurysms: a systematic review and meta-analysis.

This systematic review and meta-analysis compared microsurgical clipping with Woven EndoBridge (WEB) embolization for ruptured and unruptured intracranial aneurysms.

Neurosurg RevOct 17, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Gamma-irradiated amniotic membrane graft as an adjuvant to posterior colporrhaphy: an exploratory prospective single-arm clinical trial.

This exploratory prospective, single-arm pilot clinical trial evaluated gamma-irradiated amniotic membrane grafting during posterior colporrhaphy in 25 women with posterior compartment prolapse.

BMC Womens HealthOct 17, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Switching from Intravenous to Subcutaneous Infliximab in Children with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis synthesized six independent, largely observational cohorts of children with inflammatory bowel disease who switched from intravenous to subcutaneous infliximab (n = 173).

Curr Gastroenterol RepOct 17, 2026Read summary
Clinical ResearchNeurologyOpen access

Global cognitive and verbal episodic memory impairment in the post-acute phase of anti-nmdar encephalitis: a systematic review and meta-analysis with narrative synthesis.

This systematic review and meta-analysis examined standardized cognitive outcomes in adults with cell-based-assay-confirmed anti-NMDAR encephalitis during the post-acute or convalescent phase.

Neurol SciOct 17, 2026Read summary
Clinical ResearchPsychiatry

The dynamic interplay between subjective and objective cognitive performance and their impact on the prognosis of major depressive disorder: A cross-lagged panel network analysis.

This cross-lagged panel network analysis examined how subjective and objective cognition related to depressive symptoms and 8-week clinical course in patients with major depressive disorder.

J Affect DisordOct 17, 2026Read summary
Clinical ResearchNeurologyOpen access

Gene-based association analysis of depression risk among European ancestry Parkinson's disease patients.

This gene-based association analysis and meta-analysis examined common and low-frequency genetic variants related to depression among European-ancestry patients with Parkinson’s disease (PD) in three population-based…

Hum GenetOct 17, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Reducing period poverty through interventions, innovations, policies and multilevel barriers and facilitators: A systematic review.

This systematic review synthesised evidence on menstrual health interventions, innovations, policies, and barriers and facilitators related to period poverty in low-, middle-, and high-income countries.

Glob Public HealthOct 17, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Periconceptional and early-pregnancy exposure to SGLT2 inhibitors and congenital malformations: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed observational cohort evidence on preconception or early-pregnancy SGLT2 inhibitor exposure among women with type 2 diabetes.

EndocrineOct 17, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effect of ultrasound-guided visual biofeedback performed by midwives on duration of second stage of labor: randomized controlled trial.

This single-center randomized controlled trial evaluated transperineal ultrasound (TPUS)-guided visual biofeedback for coached pushing by midwives in nulliparous women with term singleton pregnancies receiving epidural…

Ultrasound Obstet GynecolOct 17, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

The long-term and spillover effects of a radio drama on HIV knowledge, expressed stigma, willingness to disclose, and political priorities: Evidence from a cluster-randomized trial in Tanzania.

This placebo-controlled cluster-randomized trial tested whether a radio drama about HIV disclosure and treatment had lasting effects in rural Tanzanian villages.

Soc Sci MedOct 17, 2026Read summary
Clinical ResearchHematology

Non-Relapse Mortality With Bispecific Antibodies in Hematologic Malignancies: A Dual Systematic Review and Pharmacovigilance Analysis.

This systematic review and meta-analysis, supplemented by a pharmacovigilance analysis of FAERS, assessed non-relapse mortality (NRM) and other toxicities with bispecific antibodies in relapsed/refractory hematologic…

Hematol OncolOct 17, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Duration of single-agent perioperative antibiotic prophylaxis and postoperative meningitis after endoscopic endonasal skull base surgery: a systematic review and meta-analysis of 7,981 patients.

This systematic review and meta-analysis examined postoperative meningitis after endoscopic endonasal skull-base surgery in 7,981 patients across 14 studies using single-agent perioperative antibiotic prophylaxis.

Neurosurg RevOct 17, 2026Read summary
Clinical ResearchCardiology

Changing global prevalence of diuretic resistance amongst patients with heart failure: a systematic review and cumulative meta-analyses.

This systematic review and cumulative meta-analysis assessed diuretic resistance (DR) prevalence in adults with heart failure.

Curr Probl CardiolOct 17, 2026Read summary
Clinical ResearchOrthopedic Surgery

Patient-Reported Outcomes after Distal Radius Fractures Differ Across Geographic and Cultural Populations: A Global Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined whether patient-reported outcomes after volar locking-plate fixation of adult distal radius fractures varied across cultural and geographic populations.

J Orthop TraumaOct 17, 2026Read summary
Clinical ResearchOncology (Medical)Open access

PD-1/ PD-l1 Inhibitors and Stereotactic Radiosurgery for Brain Metastases: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed efficacy and toxicity when PD-1/PD-L1 inhibitors were combined with stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) for…

Clin Exp MetastasisOct 17, 2026Read summary

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