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1003 articles
May 202620
Hospital dental management as an adjunct to systemic therapy in refractory oral candidiasis in severe combined immunodeficiency.
A 15-month-old male with X-linked severe combined immunodeficiency (SCID) presented with persistent oral and esophageal candidiasis despite prolonged systemic antifungal treatment.
Sex-related disparities in sepsis in western Europe: A systematic review and meta-analysis.
This systematic review and meta-analysis examined sex-stratified mortality and infection patterns among adults with sepsis in Western Europe. It included 18 studies with 671,861 participants.
Ceftriaxone for methicillin-susceptible Staphylococcus aureus bloodstream infections is associated with increased short-term mortality: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of ceftriaxone compared to antistaphylococcal penicillins or cefazolin in treating methicillin-susceptible Staphylococcus aureus bloodstream infections…
Dihydroartemisinin-piperaquine versus chloroquine for the treatment of uncomplicated Plasmodium vivax malaria with concurrent or delayed high-dose primaquine in Brazil (Curavivax): an open-label, single-centre, randomised clinical trial.
This open-label, single-centre, randomised trial evaluated dihydroartemisinin-piperaquine versus chloroquine for treating uncomplicated Plasmodium vivax malaria in Brazil.
Solitary ulcer at the mons pubis in a heterosexual male patient.
A 54-year-old heterosexual male presented with a solitary, indurated ulcer on the mons pubis, following minimal trauma from shaving three weeks prior.
Safety and Immunogenicity of Varicella Vaccination in Children and Adolescents Living With HIV: A Systematic Review.
This systematic review evaluated the safety and immunogenicity of varicella vaccination in HIV-positive children. Analyzing 18 studies, it found that local reactions occurred in less than 21% of vaccinees after the…
Dual arthropathy in previously treated multibacillary leprosy: Inflammatory polyarthritis with neuropathic ankle destruction in an endemic setting.
A 51-year-old woman with a history of multibacillary leprosy presented with polyarthritis affecting her wrists, ankles, and small joints of the hands, mimicking rheumatoid arthritis.
Construction of a "three-stage and four-level" evaluation system for cerebrospinal fluid pathogens based on mNGS: insights from a case of co-detection of Cryptococcus and Epstein-barr virus.
A patient with central nervous system symptoms underwent metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF), revealing co-detection of Cryptococcus and Epstein-Barr virus (EBV).
Effectiveness of chlorhexidine gluconate-impregnated dressings in preventing central line-associated bloodstream infection in a paediatric intensive care unit: A randomised controlled trial.
This randomized controlled trial evaluated the effectiveness of chlorhexidine gluconate (CHG)-impregnated dressings in preventing central line-associated bloodstream infections (CLABSI) in 250 pediatric patients in a…
Effective Alternative Treatment Regimens for People With Infectious Syphilis: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis evaluated alternative treatment regimens for infectious syphilis in adults and adolescents. It included 14 randomized controlled trials and 20 observational studies.
Shorter- vs. longer-course antibiotics in children with acute uncomplicated UTIs: a systematic review and meta-analyses.
This systematic review and meta-analysis evaluated the efficacy and safety of shorter-course (2-5 days) versus longer-course (≥7 days) antibiotic therapy in 2010 children with acute uncomplicated urinary tract…
Same-day initiation of tenofovir alafenamide-based pre-exposure prophylaxis with drug-level feedback for transgender women in Uganda.
This randomized controlled trial assessed the feasibility of same-day initiation of emtricitabine/tenofovir alafenamide (F/TAF) PrEP among 200 HIV-negative transgender women in Uganda.
Peripheral neurological involvement due to Bartonella henselae in an immunocompetent adolescent: a case report and literature review.
A 17-year-old immunocompetent male presented with bilateral facial palsy, paresthesia, and absent deep tendon reflexes after experiencing axillary lymphadenopathy from cat scratches.
Expanding Xpert MTB/RIF Ultra and lateral flow urine lipoarabinomannan testing for diagnosis of tuberculosis among adults living with HIV admitted to hospitals in Tanzania and Mozambique (EXULTANT): a randomised controlled trial.
The EXULTANT trial, a randomized controlled trial conducted in Tanzania and Mozambique, evaluated an expanded tuberculosis screening strategy among adults living with HIV.
Prevalence of cardiometabolic diseases among ART-naïve people with HIV: A global systematic review and meta-analysis.
This systematic review and meta-analysis assessed the global prevalence of cardiometabolic diseases (CMDs) among ART-naïve people with HIV (PWH).
Potential Pharmacogenomics (PGx), Human Leukocyte Antigen (HLA) Antiviral to Cephalosporin Crossover Reaction.
A 43-year-old man with type 2 diabetes and HLA-B*57:01 positivity received intravenous cefepime for pubic symphysis osteomyelitis associated with Pseudomonas.
NVX-CoV2372, monovalent mRNA and bivalent mRNA vaccines elicit broadly cross-reactive antibodies against emerging SARS-CoV-2 variants.
The PRIBIVAC study is a randomized controlled trial assessing the immunogenicity of monovalent mRNA, bivalent mRNA, and NVX-CoV2373 vaccines in 176 triple mRNA-vaccinated adults.
Semaglutide improves markers of cardiovascular risk in people with HIV.
This phase II clinical trial investigated the effects of semaglutide on cardiovascular risk markers in 36 adults with HIV and metabolic dysfunction.
Infliximab in a Child With Relapsing Tuberculous Meningoencephalitis: A Case Report and Literature Review.
A 5-year-old child with tuberculous meningoencephalitis experienced severe drug-induced hepatitis following standard antitubercular therapy, leading to the discontinuation of treatment.
Unexpectedly aggressive human-biting behaviour of Hippobosca equina Linnaeus (Diptera: Hippoboscidae).
A person in Slovakia was bitten by a parasitic forest fly identified as Hippobosca equina. The fly showed atypically aggressive behaviour toward the human host.
April 20264
Melioidosis: Burkholderia pseudomallei technical challenges in identification and susceptibility testing in a non-endemic area.
A 69-year-old man of Thai descent presented in Sydney, Australia, with a diagnosis of melioidosis. The identification of Burkholderia pseudomallei was complicated by a misreporting as B.
A systematic review with meta-analysis on racial and ethnic disparities in acute venous thromboembolism diagnosis and management.
This systematic review and meta-analysis examined racial and ethnic disparities in the diagnosis and management of acute venous thromboembolism (VTE) among U.S. adults.
Tuberculosis versus immune-related bronchiolitis under immune checkpoint inhibitor - a diagnostic challenge.
A 53-year-old man with metastatic clear-cell renal cell carcinoma developed respiratory symptoms after receiving immune checkpoint inhibitors. Imaging revealed centrilobular nodules, and QuantiFERON testing was positive.
Chronic Active Epstein-Barr Virus Disease Causes Tubulointerstitial Nephritis and Growth Failure.
A 9-year-old girl presented with fever, malaise, anemia, kidney dysfunction, and growth retardation. Initial diagnosis was acute tubulointerstitial nephritis based on biopsy.
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