Trending archive
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937 articles
April 20269
OCE-205, a selective V1a receptor mixed agonist-antagonist, for the treatment of hepatorenal syndrome-acute kidney injury: A phase 2 randomized trial.
This phase 2, multicentre, randomized, double-blind, placebo-controlled dose-ranging trial evaluated OCE-205 in patients with hepatorenal syndrome–acute kidney injury.
Comparative diagnostic performance of advanced endoscopic techniques in suspected sarcoidosis: A systematic review and network meta-analysis.
This Bayesian network meta-analysis compared diagnostic yield and safety across endoscopic tissue-sampling techniques for suspected sarcoidosis.
A randomized, double-blind, phase 3, non-inferiority trial of pradefovir mesylate versus tenofovir disoproxil fumarate in Chinese patients with chronic hepatitis B.
This ongoing, randomized, double-blind, phase 3 non-inferiority trial compared pradefovir with tenofovir disoproxil fumarate (TDF) in adults with chronic hepatitis B at 58 sites in China.
Efficacy of two triclabendazole regimens for treating human chronic fasciolosis and a controlled efficacy trial in sheep using human-isolate metacercariae in Cajamarca, Peru.
This randomized controlled study evaluated two triclabendazole (TCBZ) regimens in 26 people with egg-positive chronic Fasciola hepatica infection in Cajamarca, Peru, and tested TCBZ in sheep infected with metacercariae…
The Sunburst Sign in the Mesentery: Unveiling the Diagnosis With ⁶⁸Ga DOTATATE PET/CT.
A 57-year-old man with abdominal pain and diarrhea had a spiculated, calcified mesenteric mass on contrast-enhanced CT, initially considered a desmoid tumor.
An Enhanced Treatment Algorithm Targeting Mucosal Healing Is Effective and Safe in Older Patients With Crohn's Disease: A Post Hoc Analysis of the REACT2 Trial.
This post hoc analysis of the randomized REACT2 trial examined whether age modified the effect of enhanced-care versus step-care algorithms in patients with Crohn’s disease.
A randomized, open-label, phase 2a study to assess the safety, pharmacodynamics, and pharmacokinetics of YAQ007 versus rifaximin in cirrhosis.
This randomized, open-label, multicenter phase 2a study compared three oral YAQ007 regimens with rifaximin in 48 patients with cirrhosis and a history of overt hepatic encephalopathy.
Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis compared eight strategies for increasing colorectal cancer screening uptake across 76 randomized clinical trials.
Histomorphological Features of a Liver Explant From an Adult With Arthrogryposis-Renal Dysfunction-Cholestasis Syndrome: A Case Report and Literature Review.
A woman in her early twenties with genetically confirmed arthrogryposis-renal dysfunction-cholestasis syndrome, carrying compound heterozygous VPS33B mutations, developed progressive liver dysfunction and…
March 202615
Collision Tumor in the Stomach: Tubular Gastric Adenocarcinoma With Metastatic Adrenocortical Carcinoma-A Rare Encounter on an Endoscopic Biopsy.
A gastric lesion was found to contain two distinct malignancies: primary tubular gastric adenocarcinoma and metastatic adrenocortical carcinoma.
A Randomized Trial Testing a Body-Focused Exposure Treatment of Functional Abdominal Pain in Children.
This randomized clinical trial compared two 10-week interventions for functional abdominal pain in 107 parent-child dyads, with children aged 5–9 years.
Colorectal neoplasia-specific amino acid profiles and their diagnostic potential: a systematic review.
This systematic review assessed amino acid alterations in colorectal cancer (CRC) and advanced precursors, and their potential as non-invasive diagnostic biomarkers.
Secondary changes in the peripheral liver due to kaposiform haemangioendothelioma in the hepatic hilum: a report of two transplant cases.
Two patients underwent liver transplantation for liver failure associated with clinically unsuspected kaposiform haemangioendothelioma (KHE) at the hepatic hilum.
Comparative efficacy and safety of bi-flanged metal stents versus lumen-apposing metal stents for endoscopic drainage of pancreatic fluid collections: a systematic review and meta-analysis.
This systematic review and meta-analysis compared bi-flanged metal stents (BFMS) with lumen-apposing metal stents (LAMS) for endoscopic ultrasound-guided drainage of pancreatic fluid collections.
Efficacy and Safety of Etrasimod in Moderate-To-Severe Ulcerative Colitis: A GRADE-Based Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This GRADE-based systematic review and meta-analysis pooled four randomized controlled trials comparing etrasimod with placebo in 1,239 adults with moderately to severely active ulcerative colitis.
Necrotizing Enterocolitis as a Rare Complication of Severe RSV Bronchiolitis in a Term Neonate: A Case Report With Narrative Review.
A previously healthy, full-term 24-day-old neonate was admitted with severe respiratory syncytial virus (RSV) bronchiolitis.
Endoscopic submucosal dissection for locally recurrent gastric neoplasia following endoscopic resection: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed salvage endoscopic submucosal dissection (ESD) for locally recurrent gastric neoplasia at or near a prior endoscopic resection scar, where fibrosis can…
AVB-114 Demonstrates Clinical Benefit in Persistent Crohn's Perianal Fistulas: Randomized Cohort Results From the Multicenter STOMP2 Trial.
The multicenter, randomized STOMP2 trial compared implantable autologous cell therapy AVB-114 with standard care in patients with Crohn’s disease and a persistent single perianal fistula after prior treatment failure or…
Recurrent pancreatitis and atypical hemolytic uremic syndrome (aHUS): an unusual presentation in childhood.
A 10-year-old boy presented with abdominal pain, vomiting, oliguria, and epigastric tenderness during acute pancreatitis accompanied by atypical hemolytic uremic syndrome (aHUS).
Pseudoxanthoma Elasticum Treated with Endoscopic Clip Hemostasis for Upper Gastrointestinal Bleeding from a Dieulafoy Lesion.
A 30-year-old woman presented with upper gastrointestinal bleeding from a Dieulafoy lesion and underwent endoscopic hemostasis.
Endoscopic Management for Non-Variceal Upper Gastrointestinal Bleeding: A Network Meta-Analysis of Randomized Controlled Trials and Cost-Effectiveness Analyses of 2 Health Care Systems.
This network meta-analysis of randomized controlled trials compared over-the-scope clips (OTSC), hemostatic powder (HP), and standard endoscopic therapy (ST) for non-variceal upper gastrointestinal bleeding.
Positive conversion of latent tuberculosis screening in patients with inflammatory bowel disease on antitumor necrosis factor alpha drugs: a systematic review and meta-analysis.
This systematic review and single-arm meta-analysis assessed positive conversion on latent tuberculosis (TB) screening among patients with inflammatory bowel disease (IBD) receiving anti-TNF therapy after a negative…
Effect of probiotic and synbiotic administration on the nutritional status of hemodialysis patients: a randomized-controlled trial.
This single-blind randomized controlled trial assessed probiotic and synbiotic supplementation in 60 maintenance hemodialysis patients over 24 weeks.
Cost-effectiveness of treatment and care of patients with gastrointestinal inflammatory diseases: a systematic review.
This PRISMA-guided systematic review descriptively synthesized 18 studies published between 2013 and 2024 evaluating treatment cost-effectiveness in Crohn’s disease and/or ulcerative colitis.
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