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2000 articles
October 202624
Vulvar High-Grade Squamous Intraepithelial Lesion in Primary Lymphedema With Severe Genital Lymphorrhea: A Case Report.
A 37-year-old woman with childhood-onset primary lymphedema developed recurrent right leg and genital swelling after 31 years of clinical quiescence, with vulvar erythema, follicular lesions, and persistent lymphorrhea.
Robot-assisted versus conventional cranial stereotactic neurosurgery: a systematic review and meta-analysis of targeting accuracy, procedural efficiency, and safety.
This systematic review and meta-analysis compared robot-assisted with conventional cranial stereotactic neurosurgery across 21 comparative studies, examining targeting accuracy, procedural efficiency, safety and…
Long-term impact of aficamten on patient-reported outcome measures in obstructive hypertrophic cardiomyopathy: results from FOREST-HCM.
This open-label extension study assessed longer-term patient-reported outcomes with aficamten in people with obstructive hypertrophic cardiomyopathy who had completed an aficamten trial.
Postoperative Pain Treatment After Pancreatic Surgery: A Systematic Review With Meta-Analyses and Trial Sequential Analyses.
This PROSPERO-registered systematic review and meta-analysis examined postoperative analgesia after total pancreatectomy, pancreaticoduodenectomy, and distal pancreatectomy.
A Randomized, Double-Blind, Placebo-Controlled Study of the PD-1 Inhibitor Cetrelimab in Chronic Hepatitis B.
This randomized, double-blind, placebo-controlled study assessed the safety, activity and pharmacokinetics of a single low dose of the PD-1 inhibitor cetrelimab in adults with chronic hepatitis B virologically…
Catheter ablation in end-stage heart failure with atrial fibrillation: an hierarchical endpoint analysis of the CASTLE-HTx trial.
This ancillary hierarchical endpoint analysis of the multicentre randomized CASTLE-HTx trial compared catheter ablation plus guideline-directed medical therapy (GDMT) with medical therapy alone in 194 patients with…
Efficacy and Safety of Short-Course Radiotherapy Alone or Combined With Consolidation Chemotherapy Versus Conventional Long-Course Chemoradiotherapy for Locally Advanced Rectal Cancer: A Meta-Analysis of Randomized Controlled Trials.
This meta-analysis of randomized controlled trials compared short-course radiotherapy (SCRT), with or without consolidation chemotherapy, against long-course chemoradiotherapy (LCCRT) for locally advanced rectal cancer.
Obesity and perioperative outcomes of robotic-assisted surgery for endometrial cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis compared perioperative outcomes after robotic-assisted surgery for endometrial cancer in patients classified as obese or non-obese by the original studies.
Controlled postoperative red wine intake versus abstinence in habitual wine drinkers undergoing elective urological surgery (WISE): a translational randomized controlled trial assessing quality of life, surgical outcomes and complications.
This single-center randomized controlled trial compared postoperative abstinence with standardized red wine intake in habitual wine drinkers undergoing elective urological surgery.
Postoperative membranous urethral length and continence recovery after robot-assisted radical prostatectomy: a Bayesian longitudinal meta-analysis.
This PROSPERO-registered systematic review and Bayesian longitudinal meta-analysis examined whether postoperative MRI-measured membranous urethral length (MUL) was associated with urinary continence recovery after…
Effect of photobiomodulation on recovery from oral soft tissue local anaesthesia in paediatric patients: a preliminary split-mouth randomized clinical trial.
This preliminary split-mouth randomized clinical trial assessed whether 810-nm diode laser photobiomodulation (PBM) shortened oral soft-tissue anaesthesia after infiltration local anaesthesia in 34 children aged 8–12…
Therapeutic plasma exchange improves survival in alcohol-related acute-on-chronic liver failure: a randomized controlled trial.
This randomized controlled trial evaluated therapeutic plasma exchange (PLEX) plus standard medical therapy versus standard therapy alone in 100 patients with alcohol-related acute-on-chronic liver failure.
A NETwork meta-analysis with COST-effectiveness evaluation of pharmacological treatments for heart failure with reduced ejection fraction: NET-COST-HFrEF.
This network meta-analysis of 47 randomized controlled trials involving 75,978 patients with heart failure with reduced ejection fraction assessed guideline-directed drug combinations and their cost-effectiveness.
Short-term effects of myofascial release with therapist-mediated transcutaneous electrical nerve stimulation in adolescent idiopathic scoliosis: an exploratory randomized controlled trial .
This assessor-blinded, exploratory randomized controlled trial evaluated short-term myofascial release with therapist-mediated transcutaneous electrical nerve stimulation (MFR-TENS) in 27 adolescents with idiopathic…
Complex cervical venous drainage with a common facial-paralaryngeal anastomosis receiving the superior thyroid vein.
A 68-year-old woman’s archived CT angiogram showed a complex right cervical venous arrangement. The common facial vein and a separate lingual–parapharyngeal–paralaryngeal channel each drained into the right internal…
Post-transplant BRAF/MEK inhibitor maintenance sustains complete remission in BRAF V600E-mutant histiocytic sarcoma.
A patient with refractory BRAF V600E-mutant histiocytic sarcoma achieved complete remission with BRAF/MEK inhibition and then underwent allogeneic stem cell transplantation.
Breastfeeding and maternal bone health 10 years postpartum: findings from the ROLO longitudinal cohort study.
This longitudinal cohort analysis examined whether breastfeeding behaviours were associated with maternal bone health 10 years after pregnancy.
MULTIMODAL IMAGING OF BENIGN LOBULAR INNER NUCLEAR LAYER PROLIFERATIONS.
A 10-year-old boy was evaluated for multiple whitish intraretinal lesions and widespread pigmented spots. Examination showed bilateral lesions at the posterior pole and midperiphery, alongside extensive grouped…
Non-Traumatic Subperiosteal Orbital Hematoma After Cardiopulmonary Resuscitation: A Case Report.
A 48-year-old woman with end-stage renal disease had a cardiac arrest during hemodialysis and received 24 minutes of CPR, with return of spontaneous circulation.
Changes in gait function associated with cerebral small vessel disease-related cognitive impairment during dual-task walking: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether dual-task (DT) gait measures distinguish people with cerebral small vessel disease-related cognitive impairment (CSVD-CI) from cognitively unimpaired controls…
A Case of Delayed Detection of Vertical Transmission of HIV-1 Due to Maternal Therapy With Long-Acting Injectable Cabotegravir Plus Rilpivirine.
A 4-month-old infant was diagnosed with HIV-1 after in utero exposure to maternal antiretroviral therapy with long-acting injectable cabotegravir plus rilpivirine (LA-CAB/RPV) during the third trimester.
Renal vein thrombosis with inferior vena cava extension and pulmonary embolism in a patient with acute pyelonephritis: a case report and updated literature review.
A previously healthy 29-year-old man presented with two weeks of left flank pain and fever. Contrast-enhanced CT showed acute left pyelonephritis and extensive renal vein thrombosis extending into the suprarenal…
An Elusive Diagnosis of Strongyloides Infection Masquerading as Daptomycin-Induced Eosinophilic Pneumonitis.
A middle-aged man with alcoholic cirrhosis developed peripheral eosinophilia, bilateral pulmonary nodules, migratory consolidative opacities, and pleural effusions while receiving daptomycin for polymicrobial…
Pars plana vitrectomy with silicone oil versus pars plana vitrectomy alone for postoperative endophthalmitis: A randomized controlled trial.
This prospective randomized controlled trial compared pars plana vitrectomy (PPV) with 1000-cSt silicone oil (SO) tamponade against PPV alone in 40 eyes with severe post-phacoemulsification endophthalmitis unresponsive…
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