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1003 articles
June 202616
Chronic papillary conjunctivitis as a novel ocular manifestation of Rickettsia felis infection: A case report.
A 27-year-old man presented with a 4-year history of unilateral papillary conjunctivitis that did not respond to multiple antibiotic treatments. Examination revealed significant conjunctival changes and eyelid laxity.
Molecular epidemiology of Pseudomonas aeruginosa in Africa: A systematic review and Meta-analysis.
This systematic review and meta-analysis examined the clonal diversity and antimicrobial resistance of Pseudomonas aeruginosa in Africa, analyzing 28 studies from 13 countries.
8% capsaicin patches for HIV-induced polyneuropathy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of 8% capsaicin patches for treating HIV-induced polyneuropathy.
Cryptosporidiosis presenting as reversible acute allograft dysfunction mimicking rejection in a renal transplant recipient.
Diarrhoeal illnesses in renal transplant recipients are common in tropical regions but may have significant implications beyond gastro-intestinal morbidity.
Safety and immunogenicity of mRNA-based mpox vaccine candidate BNT166a: an open-label, dose-escalation, first-in-human trial.
This phase 1 open-label trial evaluated the safety and immunogenicity of the mRNA vaccine candidate BNT166a in healthy adults.
Synovial Fluid Leukocyte Count and Differential Are Poor Standalone Rule-in Tests for Periprosthetic Joint Infection: Results of a Methodological Audit and Reanalysis of the 2025 Meta-analysis Underpinning the Unified Periprosthetic Joint Infection Criteria.
This meta-analysis audit evaluated the methodological rigor of the 2025 meta-analysis supporting the Unified Periprosthetic Joint Infection (PJI) Criteria.
Cutaneous P. lilacinum Hyalohyphomycosis Infection: Atypical Histomorphology in an Immunocompetent Patient.
A 73-year-old immunocompetent man presented with pruritic, pink-to-violaceous plaques and papules on his right forearm, persisting for 2-3 years.
A Case Series of Vaccine-strain Reactivation Varicella Zoster in Two Pediatric Patients Presenting With Headache and Rash.
Two immunocompetent children who had received routine varicella vaccination presented with headache and rash. Cerebrospinal fluid testing confirmed varicella zoster virus meningitis and identified the Oka vaccine strain.
First Case of Congenital Toxoplasmosis After Maternal Reinfection in Colombia: Serotyping Evidence of Reinfection by Different Strains.
An immunocompetent woman with prior Toxoplasma IgG positivity later had both IgG and IgM detected four months before pregnancy.
Successful eravacycline monotherapy for cefiderocol-resistant Acinetobacter baumannii bloodstream infection in a critically ill patient with concomitant Clostridioides difficile colitis.
An 87-year-old critically ill woman with multiple comorbidities developed a bloodstream infection caused by cefiderocol-resistant Acinetobacter baumannii during hospitalization, alongside Clostridioides difficile…
Efavirenz 400 vs 600 mg combined with lamivudine and tenofovir in treatment-naïve HIV-infected patients in China: A randomized, multi-centered, controlled trial.
This randomized controlled trial evaluated the efficacy and safety of efavirenz (EFV) 400 mg versus 600 mg, each combined with lamivudine and tenofovir, in treatment-naïve HIV-infected adults in China.
N-Ethylpentedrone: first hair detection and human metabolic profiling across multiple biological matrices using UHPLC-HRMS, molecular networking and in silico prediction.
A 29-year-old man was found deceased after using N-ethylpentedrone (NEP) in a chemsex context. Analysis of three bags containing NEP confirmed a purity above 98%.
Immune correlates analysis in NextCOVE trial for a next-generation mRNA-1283 COVID-19 vaccine.
The Phase 3 NextCOVE trial evaluated the immune correlates of the mRNA-1283 COVID-19 vaccine in over 10,000 participants aged ≥12 years.
A pragmatic randomized trial to evaluate the vaccine effectiveness of bivalent RSV prefusion F vaccine for preventing RSV hospitalizations in adults (DAN-RSV): Trial design update.
The DAN-RSV trial is a pragmatic randomized controlled trial assessing the effectiveness of the bivalent RSV prefusion F vaccine in preventing RSV-related hospitalizations among adults.
Subacute Bartonella quintana bacteremia following immunomodulatory therapy: a diagnostic challenge.
A patient with newly diagnosed dermatomyositis presented with generalized myopathy, persistent low-grade fever, and suspected endocarditis.
Endocarditis caused by Candida (Candidozyma) auris.
This report details three cases of infective endocarditis caused by Candida (Candidozyma) auris, affecting a native aortic valve, a native tricuspid valve, and a prosthetic valve.
May 20268
Characterisation of HIV-1 Gag Cytotoxic T-Lymphocyte Epitopes in the Southern African Region-A Systematic Review.
This systematic review examined HIV-1 Gag cytotoxic T-lymphocyte (CTL) epitopes in the southern African region, focusing on subtype C.
A diagnostic blind spot: false-negative IMMY CrAg LFA and CrAg SQ in an immunocompetent patient with Cryptococcus gattii meningitis.
A 43-year-old immunocompetent man presented with fever, chronic progressive headache, diplopia, and papilledema. Despite persistently negative IMMY CrAg lateral flow assays and semi-quantitative CrAg results in both…
Oral fosfomycin after carbapenems as de-escalating therapy in complicated urinary tract infections: A randomized controlled trial.
This randomized controlled trial evaluated the noninferiority of oral fosfomycin trometamol compared to continued carbapenem therapy in adults with complicated urinary tract infections (cUTIs) caused by third-generation…
Fascioliasis presenting as non-resolving liver abscess: Case series from eastern India.
A series of six cases of fascioliasis were identified in eastern India, where patients presented with acute symptoms including fever and abdominal pain.
Safety and durability of influenza and SARS-CoV-2 antibody responses through 6 months after a single dose of mRNA-1083, a multicomponent influenza and COVID-19 vaccine, in adults ≥50 years.
This phase 3 randomized controlled trial evaluated the safety and immunogenicity of mRNA-1083, a multicomponent vaccine for influenza and SARS-CoV-2, in adults aged ≥50 years.
Replication and compartmentalization of Dobrava-Belgrade virus in the central nervous system.
A heart-transplant recipient presented with a fatal neurologic disease. High-throughput sequencing revealed the presence of Dobrava-Belgrade virus in both central nervous system and peripheral specimens.
Congenital syphilis in neonates: Persistent diagnostic and treatment challenges in resource-limited settings.
Five neonates born to mothers with reactive syphilis serology were identified at a tertiary care center in northern India. All infants were asymptomatic at birth, but only two mothers received adequate treatment.
Efficacy and safety of a 4-month quabodepistat, delamanid, and bedaquiline regimen for drug-susceptible pulmonary tuberculosis: a multicentre, open-label, randomised, proof-of-concept, non-inferiority, phase 2b/c trial.
This multicentre, open-label, randomised, proof-of-concept trial evaluated a 4-month regimen of delamanid, bedaquiline, and quabodepistat (DBQ) in 122 adults with drug-susceptible pulmonary tuberculosis.
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