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1320 articles
August 202611
Clinical efficacy of deep brain stimulation for psychiatric and neurological indications on a meta-analytic level.
This meta-analysis compared active with sham deep brain stimulation (DBS) in 28 blinded randomised controlled trials across psychiatric and neurological indications.
Association between PCSK9 targeted therapy and the risk of stroke and dementia: A meta-analysis of randomized controlled trials.
This meta-analysis pooled randomized controlled trials to assess cerebrovascular and neurodegenerative outcomes with PCSK9-targeted therapy.
Bispecific Antibodies Are Associated With Progressive Multifocal Leukoencephalopathy.
This report details five patients with relapsed and refractory multiple myeloma who developed progressive multifocal leukoencephalopathy (PML following treatment with bispecific antibodies.
Quantitative susceptibility mapping in neurodegenerative diseases: An umbrella review of iron-related biomarkers and mechanisms.
This umbrella review evaluates the role of quantitative susceptibility mapping (QSM) in assessing iron-related biomarkers across various neurodegenerative diseases (NDDs), including Parkinson's disease, Alzheimer's…
Cognitive-metabolic relationship in temporal lobe epilepsy: A systematic review.
This systematic review examined the relationship between neurometabolic dysfunction and cognitive impairment in 1161 patients with temporal lobe epilepsy (TLE).
The acute effects of a single session of intermittent hypoxia on blood biomarker concentrations and sleep parameters in people with Parkinson's disease: A randomized, double-blind, crossover trial.
This randomized, double-blind, crossover trial examined acute and 24-hour effects of one intermittent hypoxia (IH) session on sleep and blood biomarkers in 15 people with Parkinson’s disease (pwPD) and 15 sex-matched…
Central Nervous System Immune Reconstitution Inflammatory Syndrome During Neutrophil Recovery in Pediatric Acute Myeloid Leukemia: A Clinical and Laboratory Observation.
An 11.5-year-old girl with acute myeloid leukemia and probable invasive pulmonary mold infection developed neurological deterioration during neutrophil recovery.
Focal Hippocampal Onset and its Effect on Surgical Outcomes: A Case Report and Case Series.
The report describes a patient with mesial temporal lobe epilepsy whose seizures were successfully controlled after ablation limited to the posterior hippocampus.
Chorea-Acanthocytosis Without Acanthocytosis: Sensory Neuronopathy and Epilepsy as Prominent Features From a Novel VPS13A Variant.
A 29-year-old woman with a novel homozygous VPS13A variant presented with drug-resistant temporal-lobe epilepsy and severe sensory neuronopathy.
A fatal ascending spinal subdural empyema due to Streptococcus intermedius in a socially vulnerable patient: Forensic perspectives on diagnostic delay and implicit bias.
A 63-year-old man with a history of repeated emergency department visits presented with persistent lower back pain and neurological symptoms.
Efficacy and safety of cannabinoids in the treatment of spasticity in multiple sclerosis: A systematic review of randomized clinical trials.
This systematic review evaluated the efficacy and safety of cannabinoids for treating spasticity in multiple sclerosis, analyzing 27 randomized controlled trials with over 3000 participants.
July 202613
Early antihypertensive therapy in acute ischemic stroke: A Meta-analysis of randomized controlled trials.
This meta-analysis evaluated the effects of early antihypertensive therapy (AHT) in 15,521 patients with acute ischemic stroke (AIS) across seven randomized controlled trials.
Modulation of heart rate and heart rate variability during animal-assisted treatment of patients in a minimally conscious state: A randomized controlled crossover study.
This randomized controlled crossover study examined the effects of animal-assisted treatment (AATx) on heart rate (HR) and heart rate variability (HRV) in 21 patients with minimally conscious state (MCS).
Intravenous thrombolysis for ischemic stroke in extended time window selected with CT perfusion: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of intravenous thrombolysis (IVT) in patients with acute ischemic stroke (AIS) treated within an extended time window (ETW) using CT perfusion…
Comparative efficacy and safety of dual antiplatelet therapy strategies defined by drug composition and treatment duration for acute minor ischemic stroke or high-risk transient ischemic attack: A systematic review and Bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis evaluated dual antiplatelet therapy (DAPT) strategies for acute minor ischemic stroke or high-risk transient ischemic attack in 50,349 patients.
Mental simulation practices in stroke rehabilitation reorganize brain connectivity: a systematic review.
This systematic review evaluated the effects of Mental Simulation Practices (MSP) on brain connectivity in stroke patients.
Sleep stage-dependent distribution of interictal epileptiform discharges in epilepsy: A systematic review.
This systematic review examined the distribution of interictal epileptiform discharges (IED) across sleep stages in 266 patients with epilepsy.
A systematic review of the current prognostic tools used to predict the survival length of people living with advanced dementia.
This systematic review evaluated prognostic tools for estimating survival in individuals with advanced dementia, analyzing data from 225,553 patients across various settings.
Pharmacological treatments of REM sleep behaviour disorder in synucleinopathies: a systematic review of effectiveness and safety.
This systematic review evaluated the effectiveness and safety of pharmacological treatments for REM sleep behaviour disorder (RBD) in synucleinopathies, including Parkinson's disease and related conditions.
Rare clinical complications following scorpion envenomation worldwide: A systematic review.
This systematic review examined rare clinical complications from scorpion envenomation, analyzing articles from 2000 to 2025.
Longitudinal neuropsychological safety assessment of biperiden treatment following traumatic brain injury.
This randomized controlled trial assessed the neuropsychological safety of biperiden in 54 patients with moderate-to-severe traumatic brain injury (TBI).
Effects of Exergame Balance Training with Variable Cognitive Motor Challenges on Serum BDNF, p-tau181, and Cognitive Functions in Adults with Mild Cognitive Impairment: A Randomized Trial.
This randomized controlled trial investigated the effects of cognitive-motor exergame balance training on serum BDNF, p-tau181, and cognitive functions in 97 adults with mild cognitive impairment (MCI).
Physical, mental and biochemical effects of probiotics in multiple sclerosis: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of probiotic supplementation on physical, mental, and biochemical outcomes in adults with multiple sclerosis (MS).
Hyperhomocysteinemia and the risk of silent brain infarcts: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the association between hyperhomocysteinemia and silent brain infarcts in 2331 patients.
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