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2000 articles
September 202624
Perioperative durvalumab plus fluorouracil, leucovorin, oxaliplatin, and docetaxel for resectable gastric and gastro-oesophageal junction adenocarcinoma (MATTERHORN): final results of overall survival and event-free survival by pathological response in a global, randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.
The MATTERHORN trial, a global, randomised, double-blind, placebo-controlled phase 3 study, evaluated the effect of perioperative durvalumab plus FLOT in 948 adults with resectable gastric and gastro-oesophageal…
Autologous hematopoietic stem cell transplantation in a patient with rheumatoid arthritis and multiple myeloma: a case-based narrative literature review.
A 50-year-old woman with a 10-year history of rheumatoid arthritis (RA) developed IgG-κ multiple myeloma (MM). After VRD induction and high-dose melphalan conditioning, she underwent autologous hematopoietic stem cell…
New Observations on a Low-Grade Diffusely Infiltrative Tumour, SMARCB1 Mutant, Arguing for a New Tumour Type.
This report details two cases of low-grade diffusely infiltrative tumour (LGDIT) in an 18-year-old and a 50-year-old male, both presenting with supratentorial lesions.
Diagnostic Superiority of 68 Ga-FAPI PET/CT Over 18 F-FDG in Restaging of Advanced Epithelioid Sarcoma.
A 58-year-old man with metastatic epithelioid sarcoma underwent restaging with 18F-FDG and 68Ga-FAPI PET/CT. Despite expanding tumor volume, established lesions showed a paradoxically lower maximum SUV on FDG imaging.
Somatostatin Receptor-Expressing Hibernoma Mimicking Malignancy on SSTR-PET in MEN1: A Diagnostic Pitfall.
A 21-year-old woman with MEN1 underwent serial somatostatin receptor (SSTR) PET imaging after curative treatment of pancreatic neoplasia, which was in complete remission.
Incidental Glioblastoma Multiforme Detected on 18 F-DCFPyL PET/CT Prostate Cancer Staging.
A 77-year-old man was referred for an 18 F-DCFPyl PET/CT scan for staging of prostate cancer. The scan demonstrated an incidental intensely avid brain lesion in the right frontal lobe.
Extraskeletal Ewing Sarcoma Involving the Abdominal Cavity and Retroperitoneum on 18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT.
Primary extraosseous Ewing sarcoma located in the abdominal cavity and retroperitoneum is rare. We report the 18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT imaging findings of intra-abdominal Ewing sarcoma.
Combined 177Lu-FAP-2286 Therapy and Chemotherapy in Extraskeletal Ewing Sarcoma With Multiple Metastases.
A 23-year-old male with metastatic extraskeletal Ewing sarcoma, who could not tolerate standard chemotherapy, was treated with 177Lu-FAP-2286 followed by reduced-dose chemotherapy.
Impact of PerioperAtive LidocAine Infusions on Enhanced Recovery After Noncardiac Surgery (IMPALA-ERAS) in an inpatient setting: rationale, design and protocol for a sequential, repeated crossover trial.
The IMPALA-ERAS trial is a single-centre, pragmatic, cluster-randomised, double-blinded, placebo-controlled study evaluating the effects of perioperative intravenous lidocaine infusions on postoperative recovery in 2290…
Camrelizumab plus nimotuzumab as second-line therapy for advanced esophageal squamous cell carcinoma: a multicenter phase II study.
This multicenter phase II study evaluated the efficacy and safety of camrelizumab plus nimotuzumab in 46 patients with advanced esophageal squamous cell carcinoma (ESCC) after first-line therapy failure.
Compliance With Ecological Momentary Assessment Among Patients With Cancer: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated compliance with ecological momentary assessment (EMA) among 13,565 cancer patients.
Multidisciplinary mHealth Rehabilitation for Patients With Abdominal Cancer Who Are Receiving Chemoradiotherapy: Randomized Phase II Trial.
This randomized phase II trial evaluated a multidisciplinary mHealth rehabilitation program for 111 patients with abdominal cancer undergoing concurrent chemoradiotherapy (CCRT).
A qualitative study of cancer survivors' exercise behaviour 4 months after a telerehabilitation program.
This qualitative study, part of a randomized controlled trial, examined the exercise behaviors of 17 cancer survivors four months after completing a telerehabilitation program.
Osimertinib With or Without Chemotherapy in Advanced Non-Small Cell Lung Cancer With EGFR and Concurrent TP53 Mutations: A Randomized Clinical Trial.
This phase 3 randomized clinical trial evaluated the efficacy and safety of osimertinib combined with chemotherapy versus osimertinib alone in 294 patients with advanced non-small cell lung cancer (NSCLC) harboring…
Readmission in patients with hematologic malignancies: A systematic review and meta-analysis.
This systematic review and meta-analysis quantified readmission rates across follow-up windows in patients with hematologic malignancies and assessed associated factors. It included 104 studies.
Suspected Donor-Site Implantation of Floor of Mouth Squamous Cell Carcinoma After Free Flap Reconstruction: A Case Report.
A 57-year-old man presented with a mass in the left floor of the mouth, diagnosed as squamous cell carcinoma (SCC). Following resection and reconstruction with a free flap, a mass developed in the left thigh scar five…
Total en bloc resection of a giant cell tumour of the cervical spine involving the vertebral artery.
A woman in her 20s presented with neck pain and was diagnosed with a giant cell tumour of the cervical spine that encased the left vertebral artery.
Diffuse skeletal and bone marrow metastases mimicking plasma cell dyscrasia in advanced lung adenocarcinoma.
A man in his late 40s presented with chest pain, cough, and dyspnoea. Imaging showed left lung collapse and pleural involvement, confirmed as pulmonary adenocarcinoma via thoracoscopic biopsy.
Frontline therapies for adult patients with newly diagnosed Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia: a systematic literature review.
This systematic review evaluated 96 studies on frontline therapies for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia (B-ALL).
Phase 1/1b open-label, first-in-human study of HER2×CD3×CD28 trispecific T-cell engager (SAR443216) in participants with R/R HER2-expressing solid tumors.
This Phase 1/1b open-label study evaluated SAR443216, a trispecific T-cell engager, in 40 participants with relapsed/refractory HER2-expressing solid tumors.
Multiple Bone Metastases Exhibiting Exceptionally High 18 F-MFBG Uptake Exceeding Physiological Bladder Activity in a Patient With Neuroblastoma.
A 6-year-old boy with high-risk neuroblastoma underwent multimodal therapy and follow-up 18F-MFBG PET/CT for treatment response assessment.
Induction and extended consolidation with daratumumab, cyclophosphamide, bortezomib, lenalidomide, and dexamethasone in patients with high-risk multiple myeloma (OPTIMUM/MUKnine): 5-year follow-up of a multicentre, externally controlled, phase 2 trial.
The OPTIMUM trial, a multicentre, phase 2 study, evaluated the effects of intensified induction and extended consolidation therapy in 107 patients with high-risk multiple myeloma.
Three Cases of Merkel Cell Carcinoma Treated With Lutetium-177 Oxodotreotide.
Three patients aged 73, 45, and 77 years with advanced Merkel cell carcinoma received lutetium-177 oxodotreotide after failure of or intolerance to immune checkpoint inhibitors and cytotoxic chemotherapy.
Safety and efficacy of Meridian sinew tuina (MST) for post-surgical upper limb lymphedema: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of Meridian Sinew Tuina (MST) for post-surgical upper limb lymphedema in breast cancer patients.
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