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1303 articles

July 202624

Clinical ResearchPsychiatry

Targeting depression before it starts: An updated systematic review and meta-analysis of preventive interventions in young adults from randomized controlled trials.

This systematic review and meta-analysis evaluated the effectiveness of psychosocial preventive interventions for major depressive disorder (MDD) in young adults aged 18-25.

J Affect DisordJul 20, 2026Read summary
Clinical ResearchGeriatrics

Artificial intelligence enabled social robotic interventions (PARO) in Australian dementia care: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of PARO-based socially assistive robotic interventions in reducing behavioral and psychological symptoms in dementia patients within Australian…

Int J Med InformJul 20, 2026Read summary
Clinical ResearchGeriatrics

Association between salivary oxytocin concentration and social loneliness in older adults: Findings from an uncontrolled pre-post multimodal intervention study.

This uncontrolled pre-post multimodal intervention study examined the relationship between salivary oxytocin levels and social loneliness in 62 older adults (average age 60+) in Spain.

PsychoneuroendocrinologyJul 20, 2026Read summary
Clinical ResearchPsychiatryOpen access

The effect of monetary versus point-based rewards on effort-cost decision making in individuals at clinical high risk for psychosis.

This randomized controlled trial examined the effects of monetary versus point-based rewards on effort-cost decision-making in individuals at clinical high risk for psychosis (CHR) and healthy controls.

Schizophr ResJul 20, 2026Read summary
Clinical ResearchGeriatrics

Intelligent assistive technology for people with dementia: A meta-analysis.

This meta-analysis evaluated the effectiveness of intelligent assistive technology (IAT) in improving the quality of life for individuals with dementia, analyzing data from 12 studies involving 732 participants.

Geriatr NursJul 20, 2026Read summary
Clinical ResearchOncology (Medical)

Burdened and Burned Out: Health Behavior Disruptions in Neuro-Oncology Caregivers.

This analysis of baseline survey data from a randomized controlled trial examined perceived health-behavior changes among 116 caregivers of patients with primary brain tumors.

J Palliat MedJul 20, 2026Read summary
Clinical ResearchNeurologyOpen access

A systematic review of neuroimaging studies of adults aged 35 and older with clinical, symptomatic and genetic risk for attention-deficit/hyperactivity disorder.

This systematic review examined neuroimaging studies of adults aged 35 and older with clinical, symptomatic, or genetic risk for ADHD.

Dialogues Clin NeurosciJul 19, 2026Read summary
Clinical ResearchPsychiatry

Combination pharmacotherapy in psychotic depression: A systematic review and pairwise meta-analysis of randomized trials.

This systematic review and pairwise meta-analysis evaluated the efficacy of combination pharmacotherapy in treating psychotic depression.

J Affect DisordJul 18, 2026Read summary
Clinical ResearchPsychiatry

Resting magnetoencephalography alterations in severe mental illnesses: A systematic review.

This systematic review examined resting-state magnetoencephalography (MEG) findings in schizophrenia, major depressive disorder (MDD), and bipolar disorder.

Neurosci Biobehav RevJul 18, 2026Read summary
Clinical ResearchPsychiatry

Gambling disorder in late life: A systematic review of behavioral patterns, clinical correlates, and psychotherapeutic interventions.

This PRISMA-guided systematic review examined gambling behaviors, clinical correlates, and interventions among adults aged ≥55 years.

Am J AddictJul 18, 2026Read summary
Clinical ResearchPsychiatry

Continuous theta-burst stimulation over the right DLPFC modulates central executive network connectivity in depression: exploratory analysis of a randomized clinical trial.

This randomized controlled trial explored the effects of continuous theta-burst stimulation (cTBS) over the right dorsolateral prefrontal cortex (DLPFC) on functional connectivity in 70 patients with major depressive…

J Affect DisordJul 17, 2026Read summary
Clinical ResearchPsychiatryOpen access

Alliance Ruptures and Psychotherapy Outcomes: A Multilevel Meta-Analysis of Their Association.

This meta-analysis examined the relationship between alliance ruptures and psychotherapy outcomes, analyzing data from 301 clients across four studies.

J Clin PsycholJul 17, 2026Read summary
Clinical ResearchPsychiatry

Cardiovascular risks in psychiatric disorders and psychiatric risks in cardiovascular disorders: implications for prevention and clinical management - a large-scale umbrella review encompassing 76 meta-analyses.

This umbrella review analyzed 76 meta-analyses to explore the co-occurrence of psychiatric and cardiovascular disorders. It found that 91.7% of prevalence estimates met moderate to strong credibility criteria.

J Psychosom ResJul 17, 2026Read summary
Clinical ResearchPsychiatry

A randomized trial of omega-3 fatty acids plus inositol versus N-acetylcysteine for the treatment of depression and mania in emotionally dysregulated youth age 5-17 with and without autism traits.

This randomized controlled trial evaluated the effectiveness of omega-3 fatty acids plus inositol (O3I) versus N-acetylcysteine (NAC) in treating depression and mania in youth aged 5-17 with emotional dysregulation…

J Affect DisordJul 16, 2026Read summary
Clinical ResearchPsychiatry

Examining early-phase symptom trajectories in interpersonal psychotherapy versus antidepressant medication for adults with depression: A dynamic time warp network analysis.

This randomized controlled trial examined symptom trajectories in adults with depression undergoing either interpersonal psychotherapy (IPT) or selective serotonin reuptake inhibitors (SSRIs) over six weeks.

J Affect DisordJul 16, 2026Read summary
Clinical ResearchPsychiatry

Serum brain-derived neurotrophic factor following oral esketamine in treatment-resistant depression: Results from a randomized placebo-controlled trial.

This randomized placebo-controlled trial examined the effects of daily low-dose oral esketamine on serum brain-derived neurotrophic factor (BDNF) levels in 54 patients with treatment-resistant depression (TRD).

J Affect DisordJul 16, 2026Read summary
Clinical ResearchPsychiatry

Cost-effectiveness analysis and cost-utility analysis of a model of integrated mental health video consultations (PROVIDE-C randomised controlled trial) for people with depression and anxiety.

This study evaluated the cost-effectiveness of integrated mental health video consultations (PROVIDE-C) for individuals with depression and anxiety in primary care in Germany, compared to treatment as usual (TAU).

J Affect DisordJul 16, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effectiveness of transcutaneous auricular vagus nerve stimulation in alleviating postpartum blues following cesarean delivery: A randomized double-blind controlled trial.

This randomized controlled trial assessed the effectiveness of transcutaneous auricular vagus nerve stimulation (taVNS) in reducing postpartum blues (PPB) in 100 women following cesarean delivery.

J Affect DisordJul 16, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Efficacy of psychological interventions for premenstrual syndrome: A systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of psychological interventions for premenstrual syndrome (PMS) in 1369 reproductive-aged women.

J Affect DisordJul 16, 2026Read summary
Clinical ResearchPsychiatryOpen access

Dampening of positive affect as an emotional contrast avoidance strategy: An experimental test of the contrast avoidance model.

This randomized controlled trial explored the Contrast Avoidance Model (CAM) in a community sample, examining how dampening positive affect may serve as a strategy to avoid negative emotional contrasts.

Behav Res TherJul 16, 2026Read summary
Clinical ResearchPsychiatry

Acute neuromodulatory effects of 1 Hz rTMS on the central autonomic network in depression: A concurrent TMS-fMRI study.

This clinical trial investigated the acute effects of 1 Hz repetitive transcranial magnetic stimulation (rTMS) on the central autonomic network (CAN) in patients with major depressive disorder (MDD).

J Affect DisordJul 16, 2026Read summary
Clinical ResearchPsychiatry

"Out of sync and overlooked" - Relationship between social jetlag and anxiety in adolescents: Systematic review and meta-analysis.

This systematic review and meta-analysis examined the relationship between social jetlag (SJL) and anxiety in adolescents aged 12-18 years.

Sleep Med RevJul 16, 2026Read summary
Clinical ResearchPsychiatryOpen access

Dose-related reductions in prefrontal recruitment during cognitive reappraisal following oral delta-9-tetrahydrocannabinol in posttraumatic stress disorder.

This randomized controlled trial examined the effects of oral delta-9-tetrahydrocannabinol (THC) on prefrontal activation during cognitive reappraisal in adults with posttraumatic stress disorder (PTSD).

NeuropsychopharmacologyJul 16, 2026Read summary
Clinical ResearchNeurology

Neuropsychiatric adverse events with anti-seizure medications in patients with epilepsy: A systematic review and meta-analysis.

This systematic review and meta-analysis synthesized observational evidence on neuropsychiatric adverse events (NPAEs) associated with anti-seizure medications (ASMs) in people with epilepsy.

Epilepsy ResJul 16, 2026Read summary

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