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1357 articles
November 202624
Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.
This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.
Efficacy of De-Epithelialized vs. Subepithelial Grafts in Periodontal Plastic Surgery for Gingival Recession: A Systematic Review and Meta-Analysis of Root Coverage Techniques.
This systematic review and meta-analysis compared de-epithelialized gingival grafts (DGG) with subepithelial connective tissue grafts (SCTG) for RT1 gingival recessions.
What Cochlear Implantation with Attempted Hearing Preservation in Widened Vestibular Aqueduct Adds to Understanding About the Etiology and Pathogenesis of Hearing Loss: A Systematic Review.
This PRISMA-compliant systematic review examined hearing preservation cochlear implantation in children with widened vestibular aqueduct (WVA), a congenital inner-ear malformation associated with childhood sensorineural…
Dirozalkib versus Crizotinib in Advanced Anaplastic Lymphoma Kinase Inhibitor-Naïve ALK -Positive Non-Small-Cell Lung Cancer: A Multicenter, Randomized Phase III Trial.
DIAMOND-2 was a multicenter, randomized, open-label phase III trial comparing dirozalkib with crizotinib in adults with ALK inhibitor-naïve, ALK-positive advanced non-small-cell lung cancer.
Spatial transcriptomics tumor microenvironment determinants of tyrosine kinase inhibitor response in renal cell carcinoma: results from a phase 2 clinical trial.
This phase 2 clinical trial examined whether spatially resolved tumor gene-expression patterns were associated with sunitinib response in 46 patients with metastatic clear cell renal cell carcinoma.
Slow-wave sleep mediates the compensatory effects of acute moderate-intensity exercise on declarative memory deficits in sleep restriction.
This randomized controlled trial tested whether one session of moderate-intensity exercise could protect declarative memory during sleep restriction and whether slow-wave sleep (SWS) mediated any benefit.
Acute doses of 3 and 6 mg/kg caffeine produce outcome- and phase-specific improvements in male 100-m sprinters: A randomized, double-blind, placebo-controlled crossover trial.
This randomized, double-blind, placebo-controlled crossover trial tested acute caffeine doses in 21 male 100-m sprinters. After placebo, 3 mg/kg, or 6 mg/kg, participants completed sprint and other performance tests.
Feasibility of robotic-assisted surgery for nutcracker syndrome: a systematic review and single-arm meta-analysis.
This systematic review and single-arm meta-analysis assessed robotic-assisted surgery for nutcracker syndrome (NCS), using 10 studies of 140 patients, mostly retrospective case series.
Non-invasive vascular assessment in gestational hypertension and preeclampsia during pregnancy and the postpartum period: a systematic review.
This systematic review evaluated non-invasive measures of vascular structure and function in women with gestational hypertension or preeclampsia during pregnancy and postpartum.
Acupuncture after surgery of soft tissue tumors of the extremities: postoperative pain and feasibility: a prospective trial.
This prospective, single-arm, single-centre pilot study assessed acupuncture feasibility and postoperative pain after extremity soft tissue tumor resection in 25 patients.
Changes in self-related cognitive processes and depressive symptom severity following a single, moderate dose of psilocybin in depressed patients.
This randomized, double-blind, placebo-controlled trial examined depressive symptoms, self-concept and neural markers of self-referential processing in 37 people with major depressive disorder.
Robotic pancreatic enucleation versus laparoscopic pancreatic enucleation: a meta-analysis.
This meta-analysis compared robotic with laparoscopic pancreatic enucleation for perioperative outcomes. It pooled five cohort studies involving 272 patients (128 robotic and 144 laparoscopic).
Micro-axial flow pump vs veno-arterial extracorporeal membrane oxygenation for high-risk percutaneous coronary interventions: a randomized trial.
This prospective, multicentre, randomised, open-label non-inferiority trial compared prophylactic SynFlow 3.0 micro-axial flow pump support with VA-ECMO during non-emergent high-risk PCI in patients with complex…
Combined Immunotherapy and Hybrid Dose-Fraction Radiotherapy for Driver-Negative Metastatic NSCLC: A Phase II Trial with Parallel Preclinical Studies.
This single-arm, multicenter phase II trial evaluated hybrid dose-fraction radiotherapy added during first-line chemoimmunotherapy maintenance in 83 patients with stage IV driver-negative metastatic NSCLC.
Brain MRI changes following continuous positive airway pressure therapy in adults with obstructive sleep apnea: a systematic review.
This systematic review synthesized longitudinal brain MRI studies in adults with obstructive sleep apnea (OSA) before and after continuous positive airway pressure (CPAP), including comparisons with control groups.
Cardiovascular outcomes of glucagon-like peptide-1 receptor agonists: A systematic review.
This systematic review evaluated 12 cardiovascular outcome-based randomised controlled trials of GLP-1 receptor agonists (GLP1RAs): 10 in people with type 2 diabetes (T2D), one in people with overweight or obesity and…
Outcomes in the BETAMI-DANBLOCK trial compared with a Norwegian nationwide myocardial infarction population.
This transportability analysis compared participants in the BETAMI and DANBLOCK randomized trials with revascularized Norwegian patients who had myocardial infarction, LVEF ≥40%, and no heart failure.
Comparison of alignment in patients with buccally displaced maxillary canines using T-loop mechanics and continuous arch mechanics: a randomized clinical trial.
This parallel, two-arm randomized clinical trial compared T-loop mechanics (TLM) with continuous arch mechanics (CAM) for aligning maxillary anterior teeth in 26 patients with unilateral or bilateral buccally displaced…
Efficacy and safety of apixaban versus rivaroxaban in acute venous thromboembolism: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared apixaban with rivaroxaban for acute venous thromboembolism in adults.
The effect of listening to Qur'an on quality of life and sleep quality in breast cancer patients undergoing chemotherapy: a randomized controlled trial.
This open-label, participant-level randomized controlled trial with blinded statistical analysis examined whether listening to Qur’an during chemotherapy affected patient-reported quality of life and sleep in women with…
Severity-Based Triage for Direct Transportation to Nearest Comprehensive Stroke Center: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed prehospital bypass of the nearest stroke center for direct transport to a more distant comprehensive stroke center in patients with suspected stroke.
A flap with its own blood supply: robot-assisted appendiceal ureteroplasty for complex ureteral strictures-a systematic review and single-arm meta-analysis.
This systematic review and single-arm proportional meta-analysis assessed the success and safety of robot-assisted appendiceal ureteroplasty (RAU) for complex upper- and mid-ureteral strictures in adults.
Effect of orofacial myofunctional therapy with auto-monitoring on the apnea-hypopnea index in patients with mild-to-moderate obstructive sleep apnea: a multicenter randomized controlled trial.
This multicenter randomized controlled trial assessed standardized orofacial myofunctional therapy (OMT) in treatment-naive adults with mild-to-moderate obstructive sleep apnea.
Impact of early versus delayed mobilization after arthroscopic rotator cuff repair in small and medium-sized tears: a prospective randomized study.
This prospective randomized study compared early with delayed mobilization after arthroscopic single-row knotless repair of small and medium full-thickness supraspinatus tears in 70 patients aged 20–70 years.
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