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412 articles
October 202624
Hyaluronic acid-based skin booster with glutathione combined with 1064-nm Nd:YAG laser and oral tranexamic acid for melasma: A prospective comparative study.
This randomized comparative study evaluated whether intradermal hyaluronic acid-based glutathione (HA-GSH) improves outcomes when added to low-fluence 1064-nm Q-switched Nd:YAG laser and oral tranexamic acid in Chinese…
A Prospective, Multicenter, Evaluator-Blind, Randomized, Comparator-Controlled Study of Belotero Intense (+), a Hyaluronic Acid Filler With Lidocaine, for Lip Augmentation.
This multicenter, evaluator-blind randomized comparator-controlled equivalence trial assessed Belotero Intense with lidocaine (BIL) for lip augmentation in patients with lip volume deficits, comparing it with Restylane…
Focal Epithelial Hyperplasia in a Somali Child: A Case Report and Review of Management with Topical Imiquimod.
An 8-year-old Somali girl had a 3.5-year history of asymptomatic, progressively increasing oral lesions. Examination showed multiple soft, flat-topped verrucous papules on the lower labial, buccal and lingual mucosa and…
The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review.
This qualitative systematic review assessed cannabidiol (CBD) for cutaneous wound healing, including in vivo studies and clinical trials identified through searches of seven databases. Six studies were included.
Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.
Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.
Targeting an IL-17/IL-36 pathogenic hub in hidradenitis suppurativa with a bispecific antibody.
This phase I/II proof-of-concept clinical trial evaluated HB0043, a bispecific antibody targeting IL-17A and IL-36R, in patients with severe, tunnel-dominant Hurley Stage III hidradenitis suppurativa.
Fecal microbiota transplantation for the treatment of neurogenic rosacea: protocol of a randomized, blinded, placebo-controlled explorer study.
This publication describes the protocol for a single-center, randomized, double-blind, placebo-controlled exploratory trial of fecal microbiota transplantation (FMT) in patients with neurogenic rosacea, a phenotype…
Multiple-Staged Versus Single-Stage Surgical Excision for the Reconstruction of Congenital Melanocytic Nevi: A Meta-Analysis of Efficacy and Safety.
This meta-analysis compared multiple-staged with single-stage excision and reconstruction for congenital melanocytic nevi (CMN). It pooled seven retrospective cohort or clinical controlled studies involving 578 patients.
Outcomes and Predictors of Sustained Response After Dose Tapering of Targeted Therapies in Moderate-to-Severe Atopic Dermatitis: A Systematic Review.
This systematic review examined dose tapering or withdrawal of biologics and small-molecule inhibitors in moderate-to-severe atopic dermatitis (AD), including 19 studies and 4375 patients.
Clinical translation of polymeric microneedles for bioactive nanovesicle delivery in hypertrophic scar remodeling.
This prospective, single-center, open-label, single-arm study evaluated a 12-week protocol combining microplasma radiofrequency, poly(L-lactic acid) microneedles, and topical milk-derived bioactive nanovesicles in 26…
Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.
This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.
Long-Term Follow-Up of Epidermolysis Bullosa Acquisita with Fluctuations in Serum Cytokine Levels: A Case Report.
A 47-year-old man with epidermolysis bullosa acquisita (EBA) had a disease course lasting more than 10 years. Serial testing showed that anti-basement membrane zone IgG and anti-type VII collagen antibody titers…
Lamotrigine-associated SJS/TEN overlap during valproate co-therapy managed with rhTNFR-Fc and therapeutic plasma exchange: A case report.
A 49-year-old man receiving valproate developed fever and a rapidly spreading erythematous maculopapular eruption after lamotrigine was started at 50 mg once daily.
Effect of pre-visit computer-assisted history-taking with a structured copy-ready summary on documentation completeness in screening for inflammatory rheumatic diseases: a randomized pilot study.
This multicenter, parallel-group randomized pilot study assessed pre-visit computer-assisted history-taking (CAHT) with a structured, copy-ready summary in adults at increased risk of inflammatory rheumatic disease…
Clinical Efficacy of 5-Aminolevulinic Acid Photodynamic Therapy Combined With Interferon Spray in Treating Common and Plantar Warts.
This randomized controlled trial evaluated the efficacy of 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) combined with recombinant human interferon alpha 2b (rhIFN-α2b) spray in 104 patients with refractory…
Janus kinase inhibitors in the management of lichen planus: a systematic review.
Lichen planus (LP) is a chronic, lymphocytic, inflammatory skin disorder that can affect the skin, hair follicles, nails, and mucous membranes. It has limited treatment options.
A 45-Year-Old Woman With 30-Year History of a Nodule of the Earlobe Diagnosed as Lupus Vulgaris (Cutaneous Tuberculosis).
A 45-year-old woman had a painless, intermittently itchy lesion on her right earlobe for more than 30 years. It appeared as a red, thickened plaque with yellow papules and pustules.
Safety, Efficacy, and Immunogenicity of a Multivalent Adjuvanted Staphylococcus aureus Vaccine in Adults With Recent Skin and Soft Tissue Infections: An Observer-Blind, Randomized, Placebo-Controlled, Multinational Phase 1/2 Trial.
This observer-blind, randomized, placebo-controlled phase 1/2 trial evaluated a five-antigen Staphylococcus aureus vaccine with AS01E adjuvant in adults, including 194 participants aged 18–64 years with a recent S.
Acrokeratosis paraneoplastica (Bazex syndrome): a systematic review and quantitative analysis of 106 cases.
Acrokeratosis paraneoplastica (Bazex syndrome) is an obligate paraneoplastic dermatosis characterized by symmetrical acral psoriasiform lesions and nail dystrophy.
Cutaneous leukocytoclastic vasculitis with concurrent colitis of uncertain aetiology.
A female in her 20s presented with biopsy-confirmed cutaneous leukocytoclastic vasculitis and significant gastrointestinal symptoms, including recurrent rectal bleeding and abdominal pain.
Nephrotic range proteinuria and rapid progression to end-stage kidney disease in seronegative pauci-immune necrotizing glomerulonephritis masked by cutaneous lesions: a case-based review.
A 22-year-old woman with a history of recurrent cutaneous lesions was hospitalized due to exacerbation of her skin condition. Laboratory tests revealed nephrotic-range proteinuria and reduced eGFR.
Geographical and temporal patterns of cutaneous leishmaniasis in Pakistan: insight from a decade of epidemiology.
This systematic review examined the geographical distribution and epidemiological trends of cutaneous leishmaniasis (CL) in Pakistan from 2014 to 2024.
Treatment of hypertrophic scars using fractional CO2 laser alone in comparison with adding botulinium toxin either intalesional injection or assisted drug delivery.
This randomized controlled trial evaluated the effectiveness of fractional CO₂ laser treatment alone versus its combination with botulinum toxin A in 16 patients with post-burn hypertrophic scars.
Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).
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