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470 articles

October 202624

Clinical ResearchPediatricsOpen access

Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.

This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.

Eur J PediatrOct 23, 2026Read summary
Case ReportAnesthesiologyOpen access

Low-Dose Epidural Hydromorphone as an Adjunct to Ropivacaine for Intraoperative Visceral Traction Pain During Elective Cesarean Delivery: A Randomized, Double-Blind, Placebo-Controlled Trial.

Visceral traction during cesarean delivery may cause pain, nausea, and autonomic activation despite an adequate neuraxial block.

Drug Des Devel TherOct 23, 2026Read case
Clinical ResearchGastroenterologyOpen access

Adjunctive Oliceridine During Propofol or Ciprofol Sedation for Same-Session Bidirectional Endoscopy in Older Adults: A Multicenter Randomized 2×2 Factorial Trial.

This multicenter, double-blind, placebo-controlled 2×2 factorial randomized trial assessed adjunctive oliceridine with propofol or ciprofol for same-session bidirectional endoscopy in adults aged 65–80 years.

Drug Des Devel TherOct 23, 2026Read summary
Case ReportAnesthesiologyOpen access

Opioid-Free versus Opioid-Based Anesthesia for Quality of Recovery After Knee Arthroscopy: A Randomized Non-Inferiority Trial.

We determined whether dexmedetomidine- and esketamine-based opioid-free anesthesia (OFA) was non-inferior to opioid-based anesthesia (OA) for 24-hour Quality of Recovery-15 (QoR-15) after elective knee arthroscopy with…

Drug Des Devel TherOct 23, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Combined transcutaneous electrical nerve stimulation and low-level laser photobiomodulation for postoperative pain after cesarean section: A randomized controlled trial.

This randomized controlled trial compared combined transcutaneous electrical nerve stimulation (TENS) and low-level laser photobiomodulation (PBM) with TENS alone, placebo, and control for postoperative recovery after…

PLoS OneOct 22, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Bolus-only versus bolus plus continuous infusion hydromorphone for refractory cancer pain: a prospective, multicenter, randomized noninferiority trial.

This prospective, multicenter, randomized noninferiority trial compared bolus-only patient-controlled intravenous hydromorphone analgesia with bolus plus continuous infusion in patients with refractory cancer pain.

Support Care CancerOct 22, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Clinical safety, tolerability, and efficacy of fospropofol disodium for sedation: a systematic review.

This systematic review and meta-analysis assessed randomized trials of fospropofol for procedural and ICU sedation. It included 10 studies: six procedural-sedation trials and four ICU-sedation trials.

Eur J Clin PharmacolOct 22, 2026Read summary
Case ReportAnesthesiology

Anaesthetic Management of a Child with Chromosome 7q32.1 Microdeletion Undergoing Ligation of Patent Processus Vaginalis.

A six-year-old boy with chromosome 7q32.1 microdeletion, autism spectrum disorder, attention deficit hyperactivity disorder, hypotonia and asthma underwent elective ligation of a patent processus vaginalis under general…

Ir Med JOct 22, 2026Read case
Case ReportAnesthesiologyOpen access

Prophylactic Low-Dose Esketamine for Prevention of Intraoperative Penile Erection During Ureteroscopic Surgery Under General Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial.

Intraoperative penile erection (IPE) during ureteroscopic surgery may interrupt surgical procedures and increase the risk of urethral injury.

Drug Des Devel TherOct 21, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Tranexamic acid in laparoscopic sleeve gastrectomy: bleeding control amid thrombotic concerns and hemodynamic instability: a randomized double-blinded clinical trial.

This randomized, double-blinded clinical trial assessed tranexamic acid (TXA) for perioperative bleeding prevention in 185 patients with morbid obesity undergoing elective laparoscopic sleeve gastrectomy.

Acta Cir BrasOct 19, 2026Read summary
Clinical ResearchAnesthesiology

The Impact of Anaesthesia Method on the Use of Anaesthesia Department Resources in Total Knee Arthroplasty.

This randomised controlled trial compared spinal anaesthesia with general anaesthesia using total intravenous anaesthesia in 395 patients undergoing total knee arthroplasty.

Acta Anaesthesiol ScandOct 18, 2026Read summary
Case ReportAnesthesiology

Multiple Recurarization Episodes After Sugammadex Reversal in Hyperthermic Intraperitoneal Chemotherapy: A Case Report.

A 53-year-old woman undergoing hyperthermic intraperitoneal chemotherapy (HIPEC) experienced three sequential episodes of recurarization after reversal of rocuronium-induced neuromuscular blockade with sugammadex 5.4…

A A PractOct 16, 2026Read case
Clinical ResearchAnesthesiology

Nociception Level-Guided Multimodal Analgesia with External Oblique Intercostal Plane Block in Laparoscopic Cholecystectomy.

This double-blind randomized controlled trial compared nociception level (NOL)-guided multimodal analgesia (MMA) incorporating an external oblique intercostal plane (EOIP) block with intravenous dexketoprofen alone in…

J Vis ExpOct 16, 2026Read summary
Case ReportAnesthesiology

Individualized multimodal pain management for chronic perineal pain: A case report.

A 68-year-old woman had three years of chronic perineal pain and tenderness that disrupted sleep, urination, and daily activities.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchAnesthesiology

Quality of recovery after arthroscopic meniscectomy with remimazolam or propofol anesthesia: A randomized controlled trial.

This randomized controlled trial compared propofol-based with remimazolam-based total intravenous anesthesia in adults undergoing elective arthroscopic meniscectomy.

PLoS OneOct 15, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Optimization of Anticoagulation Strategy During Cardiopulmonary Bypass in Neonates with Congenital Heart Disease: A Randomized Controlled Trial.

Neonatal hemostatic immaturity complicates anticoagulation during cardiopulmonary bypass (CPB). Current practice largely follows the strategy of 400 U/kg from adult protocols, as neonatal-specific guidelines and…

Drug Des Devel TherOct 15, 2026Read case
Case ReportCardiology

Effects of stellate ganglion blockade on pulmonary artery pressure and sympathetic baroreflex function at high altitude: a case study in treated hypertension.

A 44-year-old man with treated hypertension underwent physiological assessment at sea level and after 5–8 days at 3,800 m. High-altitude exposure was accompanied by increases in pulmonary artery systolic pressure…

J Appl Physiol (1985)Oct 15, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis.

This systematic review and meta-analysis of 16 randomized controlled trials involving 994 patients assessed anterior quadratus lumborum block (aQLB) for postoperative analgesia after hip surgery.

Balkan Med JOct 15, 2026Read summary
Clinical ResearchAnesthesiology

Pericapsular Nerve Group Block Versus Femoral Nerve Block for Analgesia in Newly Admitted Patients With Hip Fractures: A Randomized Controlled Trial.

This randomized controlled trial compared preoperative pericapsular nerve group (PENG) block with femoral nerve block (FNB) in 60 newly admitted patients with hip fractures.

Clin J PainOct 14, 2026Read summary
Case ReportAnesthesiology

Preoperative Sedation via Cecostomy Tube in an Autistic Adolescent: A Case Report.

A 13-year-old autistic boy with a preexisting cecostomy tube for chronic constipation had previously been unable to tolerate oral or intramuscular preoperative sedation because of agitation and physical aggression.

A A PractOct 14, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Perineural versus intravenous dexmedetomidine as an adjuvant for ilioinguinal/iliohypogastric nerve block in open inguinal hernia repair: a randomised controlled trial.

This single-centre, triple-blind randomised controlled trial compared perineural, intravenous and placebo dexmedetomidine as adjuncts to an ilioinguinal/iliohypogastric nerve block in 90 adults undergoing elective open…

HerniaOct 14, 2026Read summary
Case ReportAnesthesiology

Low-Volume Superior Trunk and Superficial Cervical Plexus Block With Sedation as the Sole Regional Anesthetic for Proximal Humerus Fracture Fixation in a Patient With Alzheimer Disease.

A 68-year-old woman with Alzheimer disease underwent fixation of a closed right proximal humerus fracture through a deltopectoral approach.

Am J Case RepOct 14, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effect of a Subanesthetic Dose of Esketamine on Postoperative Sleep Disturbance After Oocyte Retrieval Under Intravenous Anesthesia: A Randomized Controlled Trial.

This randomized, double-blind, placebo-controlled trial assessed whether intravenous esketamine reduces postoperative sleep disturbance (PSD) in women undergoing oocyte retrieval with intravenous anesthesia.

Drug Des Devel TherOct 14, 2026Read summary
Clinical ResearchUrologyOpen access

Opioid-free versus opioid-based anesthesia for robot-assisted radical prostatectomy: a single-center randomized controlled trial.

This single-center randomized controlled trial compared opioid-free anesthesia (dexmedetomidine plus ketamine) with remifentanil-based anesthesia in adult men undergoing robot-assisted radical prostatectomy.

J Robot SurgOct 13, 2026Read summary

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