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1320 articles
August 202624
Mitochondrial abnormalities in Charcot-Marie-Tooth disease: insights from a family harbouring a novel GDAP1 variant.
Charcot-Marie-Tooth disease is an inherited peripheral neuropathy marked by progressive loss of motor and sensory function.
Effects of neurofeedback and biofeedback on cognitive, affective, and motor outcomes in adults with multiple sclerosis: a systematic review.
This systematic review examined interventional studies of neurofeedback and biofeedback for cognitive, affective, and motor outcomes in adults with multiple sclerosis.
Corpus callosotomy in Lennox-Gastaut syndrome: Effectiveness, safety, and predictors of outcome: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed corpus callosotomy (CC) effectiveness and safety for Lennox-Gastaut syndrome (LGS), synthesizing 48 studies involving 822 patients.
A systematic review of Mendelian randomization evidence on alcohol-related phenotypes and multiple human diseases.
This systematic review synthesised Mendelian randomization studies using genetic variants as instruments for alcohol consumption, alcohol use disorder, or related measures to assess associations with health outcomes.
Myelin Oligodendrocyte Glycoprotein Antibodies in Breast Milk in a Lactating Woman With Severe Enterovirus-Associated MOGAD.
A 38-year-old lactating woman presented with severe MOGAD following enterovirus gastroenteritis. She developed a rapid decline into coma with status epilepticus, necessitating intensive care.
Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases.
This case series discusses two pediatric patients with medication-resistant epilepsy who underwent ketogenic diet therapy (KDT) while managing ileostomies.
Neuroimaging correlates of pain in Parkinson's disease: A systematic review of structural and resting-state fMRI studies.
This systematic review examined neuroimaging studies to understand pain mechanisms in Parkinson's disease (PD). It included 432 PD patients with pain, 225 without pain, and 257 healthy controls.
Efficacy and safety of MR guided-laser interstitial thermal therapy versus resective surgery for MRI-positive focal cortical dysplasia type II and tuberous sclerosis complex: A systematic review and meta-analysis.
This systematic review and meta-analysis compared the efficacy and safety of magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) and resective surgery in patients with MRI-positive focal cortical…
Clinicopathological characterisation of the first Australian family with the p.G51D SNCA mutation.
A family carrying the p.G51D SNCA mutation was identified through a community study of young-onset dementia. The proband developed parkinsonism at 38, followed by cognitive difficulties at 41 that progressed to dementia.
Resting-state EEG spectral power alterations following traumatic brain injury: a comprehensive systematic review and meta-analysis of clinical and injury-related moderators.
This systematic review and meta-analysis examined resting-state EEG spectral power after traumatic brain injury (TBI), including whether clinical and injury-related factors moderated findings.
Trans-spinal theta burst magnetic stimulation combined with treadmill training for gait disorders in Parkinson's disease: A randomized clinical trial.
This randomized, double-blind, controlled multicenter trial tested whether intermittent theta burst trans-spinal magnetic stimulation (iTB-TsMS) added to treadmill training (TT) improves gait and related outcomes in…
Bilateral Orbital Fat Hyperintensity in Early Glial Fibrillary Acidic Protein Astrocytopathy: A Case Report.
A 26-year-old woman presented with headache, fever, and bilateral ocular pain. MRI revealed hyperintensity in the bilateral orbital fat without optic nerve involvement, while initial intracranial MRI was unremarkable.
Safety, tolerability, and efficacy of alixorexton, a selective orexin 2 receptor agonist for narcolepsy type 1 (Vibrance-1): a randomised, double-blind, placebo-controlled, phase 2 trial.
This phase 2 randomized, double-blind, placebo-controlled trial evaluated the safety, tolerability, and efficacy of alixorexton, an orexin 2 receptor agonist, in 92 adults with narcolepsy type 1.
Pure visuospatial neglect due to cingulum bundle disconnection in right anterior cerebral artery infarction: a case report with diffusion tensor imaging analysis.
A 62-year-old woman experienced cognitive decline, including perseverative behavior and disorientation, following a right medial frontal acute infarction due to anterior cerebral artery occlusion.
Comparative efficacy and safety of rosuvastatin versus atorvastatin after acute ischemic stroke or transient ischemic attack: A systematic review and exploratory meta-analysis.
This systematic review and exploratory meta-analysis evaluated the efficacy and safety of rosuvastatin versus atorvastatin in patients following acute ischemic stroke (AIS) or transient ischemic attack (TIA).
Outcomes After Intervention in Radiation-Induced Carotid Artery Stenosis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed outcomes after carotid endarterectomy (CEA), transfemoral carotid artery stenting (CAS), and transcarotid revascularization for radiation-induced carotid artery…
Diagnostic value of blood p-tau subtypes in Alzheimer's disease progression and pathology: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic value of blood phosphorylated-tau (p-tau) subtypes in Alzheimer's disease (AD) progression and pathology.
Early and prolonged oral edaravone for neuroprotection in acute ischemic stroke: the ERASE-STROKE randomized controlled phase 3 trial.
The ERASE-STROKE trial evaluated the effects of early and prolonged oral edaravone (TTYP01) on functional outcomes in patients with acute ischemic stroke.
Ambient air pollution exposure and cognitive aging, mediators and possible pathways: A systematic review on the epidemiological studies.
This systematic review examined epidemiological evidence on factors that may mediate associations between ambient air pollution and cognitive aging.
A systematic review and meta-analysis of the efficacy and safety of eculizumab in AQP4-IgG-positive neuromyelitis optica spectrum disorder.
This systematic review and meta-analysis assessed eculizumab efficacy and safety in people with AQP4-IgG-positive neuromyelitis optica spectrum disorder, including phase III randomised controlled trials.
Improvement in neuropsychological function with memantine treatment among patients with systemic lupus erythematosus: a phase 2 randomised placebo-controlled clinical trial.
ClearMEMory was a multisite, phase 2 randomised, placebo-controlled trial assessing memantine for objective neuropsychological dysfunction in adults with systemic lupus erythematosus (SLE).
Neurocognitive deficits in children with polysomnographically confirmed obstructive sleep apnea: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated neurocognitive deficits in school-aged children (mean age 5-12 years) with polysomnographically confirmed obstructive sleep apnea (OSA).
Long-term outcomes of anti-CD19 CAR T cell therapy in refractory myasthenia gravis: A case series.
Three patients with severe, treatment-resistant myasthenia gravis (MG) were treated with autologous anti-CD19 CAR T cell therapy.
Risk of post-acute symptoms and conditions after SARS-CoV-2 compared with other respiratory viral infections: a systematic review and meta-analysis.
This systematic review and meta-analysis compared persistent symptoms and conditions in adults after SARS-CoV-2 infection with those following other acute respiratory viral infections.
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