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1382 articles
August 202624
Aural Squamous Papilloma in a 5-year-old: A Rare Case Report with Literature Review.
A 5-year-old boy had chronic itching, aural fullness, and a progressively enlarging warty lesion in the left external auditory canal.
Cardiac Computed Tomography Evaluation of Tetralogy of Fallot with Absent Pulmonary Valve Spectrum and Aneurysmal Pulmonary Artery Dilatation Causing Airway Compression.
A 4-year-old boy with recurrent respiratory infections underwent cardiac CT, which showed tetralogy of Fallot with a subaortic ventricular septal defect, overriding aorta, right ventricular hypertrophy, and right…
Prognostic Accuracy of the Phoenix Sepsis Criteria for Mortality in Children With Suspected Infection: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic accuracy of the Phoenix Sepsis Criteria (PSC) for in-hospital mortality in children with suspected infections.
Expanding the Neurological Phenotype of ZTTK Syndrome: A Case of Recurrent Acute Confusional Migraine.
A child with Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome, a multisystem disorder associated with pathogenic SON variants, experienced recurrent episodes of acute confusional migraine (ACM).
Secretory Phospholipase A 2 in Patients With Sickle Cell Disease Hospitalized for Vaso-Occlusive Pain Episodes.
This randomized controlled trial evaluated plasma levels of secretory phospholipase A 2 (sPLA 2) in 105 pediatric patients with sickle cell disease hospitalized for vaso-occlusive pain episodes.
Methodological Quality and Content Analysis of Clinical Practice Guidelines for Fever Management in Children With Sickle Cell Disease.
This systematic review evaluated the methodological quality and content of clinical practice guidelines (CPGs) for managing acute fever in children with sickle cell disease (SCD).
Randomized Placebo-Controlled Trial of Psyllium Fiber in Functional Abdominal Pain Disorders in Children.
This randomized controlled trial evaluated the efficacy of psyllium fiber in children aged 5-18 with functional abdominal pain disorders (FAPD), including IBS and FAP-NOS.
Effects of Virtual Reality Versus Whole-Body Vibration on Muscle Strength and Balance in Children with Duchenne Muscular Dystrophy: a Randomized Controlled Trial.
This assessor-blinded, parallel-group randomized controlled trial compared virtual reality (VR) with whole-body vibration (WBV) as additions to structured physical therapy in 50 ambulatory boys aged 6–10 years with…
The Use of Oral Nicotine Pouches in Adolescents: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined adolescent oral nicotine pouch use, including prevalence, user characteristics, associated factors, and co-use with other substances.
Feedback with Education versus Digital Otoscopy for Acute Otitis Media Diagnosis and Treatment.
This randomized controlled trial evaluated whether feedback with education, digital otoscopy, or both could reduce acute otitis media (AOM) treatment among 40 primary care pediatricians whose treatment rates exceeded…
The mutual effects on safety and immunogenicity of combined vaccination with 15-valent pneumococcal conjugate vaccine and adsorbed acellular DPT in 3-month healthy infants: A randomized, open-label, controlled, phase III clinical trial.
This phase III randomized controlled trial assessed the safety and immunogenicity of coadministering the 15-valent pneumococcal conjugate vaccine (PCV15) with the DTaP vaccine in 1110 healthy infants aged 3 months.
Clinical Heterogeneity and Long-Term Outcomes of Pediatric Gastrointestinal Stromal Tumors: A Series of Four Patients Highlighting SDH-Deficient and SDH-Intact Subtypes.
This report details four pediatric patients with gastrointestinal stromal tumors (GISTs) over 19 years. Two patients had SDH-deficient tumors, with one experiencing metastatic relapse.
Hypertensive disorders of pregnancy may increase the risk of neurodevelopmental delay in the offspring: a systematic review with meta-analysis.
This systematic review and meta-analysis examined the impact of hypertensive disorders of pregnancy (HDP) on neurodevelopmental delay in offspring.
Central Nervous System Immune Reconstitution Inflammatory Syndrome During Neutrophil Recovery in Pediatric Acute Myeloid Leukemia: A Clinical and Laboratory Observation.
An 11.5-year-old girl with acute myeloid leukemia and probable invasive pulmonary mold infection developed neurological deterioration during neutrophil recovery.
Effects of Intraoperative Nociception Monitoring during Adolescent Idiopathic Scoliosis Correction.
This multicenter randomized controlled trial evaluated whether Analgesia Nociception Index (ANI)-guided remifentanil administration during surgery for adolescent idiopathic scoliosis reduced postoperative morphine use.
Pediatric Legionnaires' disease: A case report and a review of the literature.
A 15-month-old girl, previously healthy, developed severe Legionnaires' disease after short-term corticosteroid therapy. The infection was likely acquired in a healthcare setting despite standard water safety measures.
Anterior cingulate cortex alterations in children and adolescents with Attention Deficit and Hyperactivity Disorder: a systematic review of neuroimaging studies.
This systematic review examines neuroimaging studies of the anterior cingulate cortex (ACC) in children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD).
Sexual and gender minority youth experience serious mental health risks, yet are not impacted by typically efficacious interventions: secondary mental health outcomes from randomized controlled trial (ATN 149).
This randomized controlled trial assessed secondary mental health outcomes of three HIV-prevention intervention components—automated text messaging, online peer support, and strengths-based coaching—in 895 sexual and…
ECG challenge: a Kangaroo pitfall.
An apparently irregular rhythm was observed on bedside monitoring in a 32-week preterm infant receiving high-flow nasal cannula support during kangaroo care.
Blinatumomab versus chemotherapy in pediatric B-ALL: A meta-analysis of randomized trials in relapsed and high-risk frontline disease.
This meta-analysis evaluated the efficacy of blinatumomab compared to chemotherapy in pediatric patients with relapsed/refractory or high-risk frontline B-cell acute lymphoblastic leukemia (B-ALL).
Pediatric tularemia in Denmark: a forgotten disease.
Two pediatric patients in Denmark presented with persistent fever, an eschar, and inguinal lymphadenitis, initially misdiagnosed as a common bacterial infection.
Empathic Communication in Pediatric Palliative Care: A Mixed-Methods Systematic Review.
This mixed-methods systematic review synthesized evidence on empathic communication between healthcare providers and parents in pediatric palliative care. It included 54 studies with approximately 3567 participants.
Gastrointestinal Adverse Events Following Rotavirus Vaccination in Children: A Systematic Review.
This systematic review assessed gastrointestinal adverse events after RV1 and RV5 rotavirus vaccination in children, drawing on randomised trials, meta-analyses, and case reports published from 2007 onwards.
Empowered Relief for Youth: Development, feasibility and early effectiveness of a single session pain relief skills class.
This single-arm clinical trial adapted Empowered Relief, a one-session pain-management class, for youth with chronic pain and assessed feasibility, acceptability, and preliminary outcomes.
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