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845 articles
July 202624
Laryngeal Nocardia: A Case Report.
An immunosuppressed patient presented with an obstructive laryngeal mass, for which malignancy was a key diagnostic consideration.
Delineation and Phenotypic Expansion of TOP3A-Related Mitochondrial Disease in Childhood.
The report describes four previously unreported patients with childhood-onset TOP3A-related mitochondrial disease, presenting with developmental delay, sensorineural hearing loss, cardiomyopathy with rhythm…
Lichen Sclerosus and Keloidal Morphea Overlap: A Case Report of an Unusual Nodular Presentation.
A 50-year-old woman presented with a solitary, well-circumscribed exophytic nodule on the left posterior thigh, with an ivory-colored peripheral rim and erythematous center.
Unusual B-Cell Lymphoproliferative Disorders Co-Occurring With Nonmelanoma Skin Cancer: Report of Three Cases.
The report describes three diagnostically challenging cases in which epithelial nonmelanoma skin cancers co-occurred with unusual B-cell lymphoproliferative disorders, including composite lymphomas.
Chondrosarcoma Involving the Ciliary Body and Choroid.
A 56-year-old man with hereditary multiple exostoses and prior secondary low-grade chondrosarcomas developed a superotemporal visual field defect.
Case report of Angiostrongylus costaricensis infection confirmed by histopathological examination.
A female patient from southern Brazil, with a history of bariatric surgery, presented with right lower quadrant abdominal pain and mild eosinophilia. Initial considerations included infectious colitis and neoplasia.
Anaplastic Thyroid Carcinoma With Kinase Gene Fusions: Report of 3 Cases With Corresponding Cytologic, Histologic, and Molecular Findings.
Three cases of anaplastic thyroid carcinoma (ATC) with kinase gene fusions were analyzed, revealing typical cytologic features such as marked nuclear atypia and sarcomatoid morphology.
Splenic Granulomatous Lesions Mimicking Metastases on 18 F-FDG PET/CT in a Patient With Ovarian Cancer.
A 76-year-old woman with a history of ovarian cancer underwent 18 F-FDG PET/CT due to increased CA199 levels in routine surveillance.
Diffuse cranial vault hyperostosis associated with long-term antiepileptic therapy: Autopsy findings and differential diagnostic considerations.
A 53-year-old woman with longstanding epilepsy treated with phenytoin and sodium valproate collapsed and died despite resuscitation.
Ultrasound-Guided Skin Biopsy: Application in Diagnosis of Reticulate Eruptions.
Biopsy for reticulate eruptions such as livedo reticularis and livedo racemosa representing an underlying vasculitis or vessel occlusion presents a challenge for most clinicians.
Diagnostic Accuracy of Real Time Reverse Transcriptase Polymerase Chain Reaction for Chikungunya Virus Detection: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed real-time reverse transcriptase polymerase chain reaction (RT-qPCR) protocols for detecting chikungunya virus during acute symptoms, comparing them with reference…
Bipolaris (dematiaceous) Fungal Keratitis Masquerading as Herpetic Keratouveitis with Hypopyon and Secondary Ocular Hypertension.
A 40-year-old farmer developed left-eye pain and marked visual loss after rubbing his eye following contact with vegetative material.
Tumorous Endobronchial Tuberculosis Mimicking Lung Neoplasm: A Diagnostic Challenge in a Middle-aged Female.
A 45-year-old woman with obstructive airway disease and type 2 diabetes presented with progressive dyspnea, cough, low-grade evening fever, and weight loss.
Orbital Proptosis as the Sentinel Sign of Metastatic Desmoplastic Small Round Cell Tumor: A Rare Ophthalmic Gateway to Systemic Malignancy.
A 56-year-old man presented with 15 days of rapidly progressive, painless left proptosis. Examination showed axial proptosis and peripapillary flame-shaped hemorrhages.
Endobronchial Spindle Cell Tumor of Neurogenic Origin with Coexisting Bronchial Anthracofibrosis: A Rare Case Report.
A 69-year-old nonsmoking woman with progressive breathlessness had a 45-year history of exposure to biomass smoke. CT showed right middle-lobe atelectasis with microcalcification and extensive mediastinal…
Machine Learning for Predicting Ki-67 Expression in Renal Tumors: A Systematic Review And Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of machine learning models in predicting Ki-67 expression in renal tumors, analyzing data from seven retrospective cohort studies involving…
Histopathologic Characterization of Cutaneous Oxalosis Mimicking Calciphylaxis: Diagnostic Pitfalls and Polarized Light Evaluation.
A 46-year-old woman with primary hyperoxaluria type 1, thought to be well controlled on lumasiran, was evaluated for skin lesions presumed to represent calciphylaxis.
Fine Needle Aspiration Cytology of Adenomyoepithelioma of the Breast: Cytologic Findings and Histologic Correlations.
Fine-needle aspiration (FNA) cytology was performed on a 71-year-old woman with the right breast painless tumor (12 mm in diameter). FNA smears were cellular, and two types of cells were observed as main components.
Intracholecystic Papillary Neoplasm Mimicking High-Grade Dedifferentiation in a Patient With Neuroendocrine Tumor: The Value of Dual-Tracer PET/CT.
A 50-year-old man with weight loss and fatigue was diagnosed with a grade 2 pancreatic neuroendocrine tumor with liver metastases.
Metastatic Large Cell Calcifying Sertoli Cell Tumor: A Case Report, Diagnostic Pitfalls, and Literature Review.
A 37-year-old man developed testicular pain and swelling after trauma and was initially treated for epididymitis and hydrocele.
A PRKCA-Fused Blue Melanocytoma Expressing a Truncated ALK Isoform.
A 13-year-old girl presented with a dome-shaped skin lesion on the tibia. The lesion was diagnosed as a blue melanocytoma and showed immunostaining with the ALK1A4 antibody.
Postmortem tryptase as a diagnostic marker in fatal anaphylaxis: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated postmortem serum tryptase as a diagnostic marker in fatal anaphylaxis, analyzing data from seven studies involving 105 anaphylactic deaths and 449 controls.
Hammock mitral valve in a 12-day-old female: pathophysiology, management and legal issues.
A 12-day-old female infant presented with acute heart failure due to undiagnosed hammock mitral valve (HMV), a rare congenital anomaly.
Early-onset lipoprotein glomerulopathy in a 23-month-old boy with homozygous APOE Kyoto variant.
A 23-month-old boy presented with nephrotic syndrome and severe anaemia. A family history of kidney disease, parental consanguinity and enlarged echogenic kidneys on ultrasound prompted early renal biopsy, which showed…
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