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1320 articles
September 202624
Fatal Myocarditis Relapse in a Patient with Myasthenia Gravis Treated with Efgartigimod Alfa: A Case Report.
A 39-year-old woman with AChR-positive generalized myasthenia gravis and a history of inflammatory myocarditis was treated with efgartigimod after inadequate response to intravenous immunoglobulin.
Ticagrelor-Aspirin With Thrombolysis by Infarct Patterns in Moderate Ischemic Stroke: TAPIS Subgroup Analysis.
This subgroup analysis of the TAPIS trial evaluated the impact of diffusion-weighted imaging infarction patterns on the efficacy and safety of ticagrelor-aspirin combined with thrombolysis in 1307 patients with moderate…
Investigating the influence of anti-seizure medications on aperiodic EEG activity.
This randomized controlled trial investigated the effects of lamotrigine and levetiracetam on aperiodic EEG activity in 13 healthy male volunteers.
Efficacy and safety of recombinant activated factor VII for spontaneous intracerebral Hemorrhage: a GRADE-assessed meta-analysis of randomized controlled trials using frequentist and Bayesian approaches.
This GRADE-assessed meta-analysis of seven randomized controlled trials compared recombinant activated factor VII (rFVIIa) with placebo in 2,022 patients with spontaneous intracerebral hemorrhage.
Exercise first: Acute aerobic exercise before practice selectively enhances spatial outcomes of motor learning - A systematic review and meta-analysis.
This pre-registered systematic review and random-effects meta-analysis examined whether acute aerobic exercise (AAE), performed before or after motor-task practice, differentially affects spatial and temporal…
The role of viral infections and other microbial factors in the pathogenesis of multiple sclerosis: a systematic review.
This systematic review assessed studies published from 2020 to 2025 on microbial factors and multiple sclerosis (MS) risk, activity, or progression.
Domain-specific effects of exercise types on cognitive function in healthy older adults: A systematic review with pairwise and Bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis compared exercise types for cognitive outcomes in cognitively healthy adults aged 60 years or older.
The pooled prevalence of cognitive impairment in adults with myelin oligodendrocyte glycoprotein antibody-associated disease: A Systematic Review & Meta-Analysis.
This systematic review and meta-analysis assessed cognitive impairment in adults with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), using studies with formal neuropsychological testing, and…
Life-threatening multisystem sarcoidosis with neurological, renal, ocular and autoimmune haemolytic manifestations treated with intravenous immunoglobulin, plasma exchange, cyclophosphamide and infliximab.
A patient with multisystem sarcoidosis presented with encephalopathy, acute tubulointerstitial nephritis, optic neuritis, and autoimmune hemolytic anemia, resembling a stroke.
Potential contributors to variable penetrance of NOTCH3 p.Arg1231Cys Variant.
Two patients with the NOTCH3 p.Arg1231Cys variant presented with early-onset dementia, strokes, and extensive leukoencephalopathy.
Clinical characteristics of THAP1 related dystonia: a case report with phenotypic review.
A 58-year-old man presented with dysphagia and dysarthria at age 22, followed by progressive dystonic posturing affecting his upper limbs, face, neck, and lower limbs.
The prevalence of frontotemporal dementia: a systematic review and meta-analysis.
This systematic review and meta-analysis estimated the global prevalence of frontotemporal dementia (FTD) in individuals under 65, analyzing 21 studies with 38,656,516 participants.
Hereditary connective tissue disorders in unselected patients with spontaneous cervical artery dissection: a targeted next generation sequencing approach and systematic review.
This study investigated the prevalence of clinically relevant genetic variants in 183 unselected patients with spontaneous cervical artery dissection (sCeAD) using targeted next-generation sequencing.
Safety, Immunovirologic, and Central Nervous System Effects of PD-1 Inhibition in People With HIV Without Malignancy.
This phase 1 nonrandomized clinical trial evaluated the safety and effects of a single dose of pembrolizumab in 6 individuals with virally suppressed HIV.
First Prospective, Single-Arm, Multicenter Study to Evaluate the Safety and Efficacy of the Overall Thrombectomy System for Stroke: iNedit, iNdeep, and iNtercept in Patients with Acute Ischemic Stroke (SEMTiC-01 Study).
The SEMTiC-01 study is a prospective, multicenter, single-arm trial evaluating the safety and efficacy of a novel neurothrombectomy system in 175 patients with acute ischemic stroke due to large vessel occlusion.
Chiari Decompression in Patients with Spontaneous Intracranial Hypotension: Presenting Symptoms and Treatment Response.
Seven patients with spontaneous intracranial hypotension (SIH) were initially misdiagnosed with Chiari malformation type I and underwent posterior fossa decompression.
Efficacy and safety of extended-release carbidopa-levodopa (IPX203) versus immediate-release carbidopa-levodopa for Parkinson's disease: A systematic review.
This systematic review evaluated the efficacy and safety of extended-release carbidopa-levodopa (IPX203) versus immediate-release carbidopa-levodopa in patients with advanced Parkinson's disease.
Neonatal Presentation of Suspected Vici Syndrome: A Case Report with Multisystem Features.
A newborn born to consanguineous parents, with a sibling who had died of an unspecified cause, presented with hypopigmentation, generalized hypotonia, recurrent severe infections, developmental delay, and cleft palate.
Prevalence of Slowly Expanding Lesions in Patients With Multiple Sclerosis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prevalence of slowly expanding lesions (SELs) in 4,786 patients with multiple sclerosis (MS).
Pearls & Oy-sters: DPPX Antibody-Associated Encephalitis in a Patient With Diarrhea, Tremor, Ocular Flutter, and Cognitive-Psychiatric Changes.
A 57-year-old man presented with a 2-month history of progressive gastrointestinal symptoms, followed by neurological manifestations including tremor, myoclonus, and cognitive changes.
Clinical Reasoning: A Patient With Progressive Sensory Neuropathy: Using Nerve Ultrasound and Skin Biopsy to Refine Diagnostic Reasoning.
A 74-year-old man presented with a 5-year history of progressive feet numbness followed by gait unsteadiness. Neurologic examination revealed absent tendon reflexes, markedly reduced vibration sense in the lower limbs…
P7C3 Compounds as Targeted Mitochondrial Therapeutics for Brain Disorders.
This systematic review evaluates P7C3 compounds, which activate NAMPT and enhance NAD+ levels, across various neurological disorders.
Impact of Baseline Polyneuropathy Severity on Eplontersen Efficacy in the NEURO-TTRansform Clinical Trial.
This post hoc analysis of the NEURO-TTRansform trial evaluated the effect of baseline severity of hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) on the efficacy of eplontersen.
Intrathecal Chemotherapy Through Ommaya Reservoir in Leptomeningeal Metastasis From Cervical Cancer: A Rare Case Report and Literature Review.
A 61-year-old woman with stage IVB cervical squamous cell carcinoma presented with acute headache and diplopia during systemic chemotherapy. Brain MRI indicated leptomeningeal metastasis, confirmed by CSF cytology.
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