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1320 articles
September 202624
Effects of Konjac glucosylceramides on cognitive function in cognitively unimpaired older adults with subjective cognitive concerns: a randomized, double-blind, controlled pilot study.
This 24-week randomized, double-blind, placebo-controlled pilot trial enrolled 40 cognitively unimpaired adults aged 60–80 years who reported subjective memory or cognitive decline.
Does reported sex modify the association between ambient air pollution exposure and Alzheimer's disease and related dementias? A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether reported sex modifies associations between ambient air pollution and dementia outcomes in longitudinal studies.
Neurogenic Paradoxical Vocal Fold Motion: A Systematic Review of Central and Pheripheral Nervous System Disorders.
This PRISMA-guided systematic review examined paradoxical vocal fold motion (PVFM) associated with confirmed central or peripheral neurological disorders.
Redefining the accuracy of clinical diagnosis of Parkinson's disease: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed the accuracy of clinical Parkinson’s disease (PD) diagnosis against neuropathological confirmation, comparing UKPDSBB, Gelb, and MDS-PD 2015 criteria.
Beyond Hemorrhage: A Case of Acute Dengue Infection Presenting with Budd-Chiari Syndrome and Bilateral Sensory Polyneuropathy.
A 22-year-old man with dengue IgM positivity and thrombocytopenia presented with abdominal pain, fever, vomiting, and loose stools.
New Observations on a Low-Grade Diffusely Infiltrative Tumour, SMARCB1 Mutant, Arguing for a New Tumour Type.
This report details two cases of low-grade diffusely infiltrative tumour (LGDIT) in an 18-year-old and a 50-year-old male, both presenting with supratentorial lesions.
Magnesium administration for vasospasm prevention in acute aneurysmal SAH: a multicenter randomized controlled trial.
This multicenter randomized controlled trial investigated the effect of magnesium sulfate (MgSO₄) on cerebral vasospasm (CV) prevention in 121 patients with acute aneurysmal subarachnoid hemorrhage (aSAH).
Ultrasound-Guided Cryoneurolysis for Peripherally Induced Dystonia After Non-neurological Surgery: A Case Series.
Three female patients aged 37 to 63 presented with refractory dystonia following non-neurological surgery, initially misdiagnosed as spasticity.
Rapid plaque clearance with anti-amyloid therapy for Alzheimer's disease: in consideration of donanemab treatment duration from real-world cases.
Two patients with early-stage Alzheimer's disease were treated with donanemab, achieving complete amyloid clearance as assessed by amyloid PET scans before their 6th and 9th infusions.
Non-contrast CT Markers of Hematoma Expansion and Andexanet Response in Factor Xa Inhibitor-Associated Intracerebral Hemorrhage: An Analysis from ANNEXa-I Trial.
This post hoc analysis of the randomized ANNEXa-I trial assessed non-contrast CT markers of hematoma expansion in patients with factor Xa inhibitor-associated intracerebral hemorrhage.
A Bayesian network meta-analysis of specific exercise modalities for depressive symptoms in mild cognitive impairment.
This Bayesian network meta-analysis compared exercise modalities for depressive symptoms in people with mild cognitive impairment (MCI), drawing on 19 randomized controlled trials of nine modalities.
Dyskinesias induced by focused ultrasound subthalamotomy in Parkinson's disease are associated with better patient impression of change.
This study examined whether dyskinesias after unilateral MR-guided focused ultrasound subthalamotomy were associated with outcomes in 34 patients with asymmetric Parkinson’s disease enrolled in a randomized controlled…
Diagnostic and Predictive Value of Circulating and Exosomal microRNAs in Ferroptosis-Associated Neurological Conditions: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic and predictive value of circulating and exosomal microRNAs (miRNAs) in ferroptosis-associated neurological conditions.
Synaptic vesicle glycoprotein 2A PET imaging in parkinsonian α-synucleinopathies: a systematic review.
This systematic review evaluated the use of synaptic vesicle glycoprotein 2A (SV2A) PET imaging in assessing presynaptic integrity in parkinsonian α-synucleinopathies, including Parkinson's disease (PD), Parkinson's…
Low-dose ticagrelor combined with aspirin for preventing early neurological deterioration in patients with high-risk non-disabling ischemic cerebrovascular events: a multicenter, prospective, randomized, open-label, clinical trial.
This multicenter, prospective, randomized trial evaluated the efficacy of low-dose ticagrelor (60 mg twice daily) plus aspirin versus clopidogrel plus aspirin in preventing early neurological deterioration (END) in 334…
Simultaneous Acute Multiple Ischemic Strokes of the Left Cerebral Hemisphere and Signs of Acute Anterior STEMI: A Case Report.
A 62-year-old man presented with right-sided limb weakness and speech difficulties, without chest pain. He was diagnosed with acute anterior ST-segment elevation myocardial infarction and acute occlusion of the left…
Prion disease mimicking rapidly progressive Alzheimer disease: case series and systematic review.
Prion disease and Alzheimer disease (AD) are common causes of rapidly progressive dementia (RPD). Although most patients with prion disease are distinguished by MRI and CSF findings, selected cases mimic rapidly…
Delusional infestation in Parkinson disease: a case report of medication-induced psychosis.
A 66-year-old woman with Parkinson disease developed visual and tactile delusions of a parasitic infestation while on dopaminergic therapy.
High-Resolution Ultrasound for Diagnosing Severity of Traumatic Peripheral Nerve Injuries-in-Continuity: A Systematic Review, Meta-Analysis of Individual Participants' Data, and Illustrative Patient Series.
High-resolution ultrasound (HRUS) may help evaluate traumatic peripheral nerve injuries (PNIs), but the sonographic features that distinguish low- from high-grade injury remain poorly defined.
Glymphatic system alterations in schizophrenia evaluated by the DTI-ALPS index: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed glymphatic-system function in schizophrenia using the DTI-ALPS index, a surrogate marker, across eight studies comparing patients with healthy controls.
Vagus nerve stimulation in pediatric patients with Lennox-Gastaut syndrome: a systematic review.
This systematic review assessed the efficacy and safety of vagus nerve stimulation (VNS) for refractory Lennox-Gastaut syndrome in pediatric patients, drawing on observational studies and case series.
Epidemiology, risk determinants, and research trends of dementia in Saudi Arabia: A systematic review.
This systematic review synthesized 55 studies of dementia epidemiology, risk factors, awareness, comorbidities, caregiving, and research trends in Saudi Arabia. Alzheimer’s disease was the most commonly reported subtype.
Pathogenicity of NUSAP1 Variants Is Defined by NMD-Escape: Evidence From Two Novel Cases and Systematic Population-Based Variant Analysis.
Two individuals with heterozygous de novo nonsense variants in the penultimate or last exon of NUSAP1 presented with early-onset refractory epilepsy, global developmental delay, congenital microcephaly, and a…
Safety and efficacy of anti-CD20 monoclonal antibodies versus teriflunomide in relapsing multiple sclerosis: a systematic review and meta-analysis.
This systematic review and meta-analysis compared anti-CD20 monoclonal antibodies with teriflunomide in adults with relapsing multiple sclerosis.
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