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1003 articles
August 202624
Photo Quiz: Globose Yeast-Like Forms With Multiple Peripheral Buds in Urine and Cervical Cytology.
A 26-year-old immunocompetent woman with a history of low-grade papillary urothelial carcinoma presented with upper abdominal pain.
Multiple Subcutaneous Nodules Caused by Plant Fungus Thyridium flavostromatum in an Immunocompromised Patient.
A man with rheumatoid arthritis receiving immunosuppressants developed multiple tender subcutaneous nodules. Aspirate showed yeast-like cells with chlamydospores, but the organism was not identified by the…
Chronic Melioidosis Presenting with Pneumonia, Empyema, and Splenic Abscess.
A patient with recurrent chest pain, cough, and abdominal discomfort over 11 months had initially been treated for a common bacterial infection.
Tuberculous Arthritis Diagnosed by Metagenomic Sequencing after Negative Microbiology Studies and a 4-Year Delay.
A 70-year-old man receiving treatment for lung cancer had chronic left knee pain and recurrent swelling. Two arthroscopic procedures were performed, but repeated standard tuberculosis tests were negative.
suPAR as a circulating inflammatory biomarker: time for translation into clinical practice - A systematic review.
This systematic review examines soluble urokinase-type plasminogen activator receptor (suPAR) as a circulating biomarker, its isoforms, and methods used to measure it.
Disseminated Salmonella infection associated with secondary seeding of an indwelling central venous catheter during chemotherapy-induced neutropenia.
A patient undergoing outpatient chemotherapy for a gynecological malignancy developed a disseminated Salmonella infection, likely acquired from fresh confectionery.
Diagnostic accuracy of bronchoalveolar lavage fluid-based testing for pulmonary cryptococcosis: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of bronchoalveolar lavage fluid (BALF)-based testing for pulmonary cryptococcosis.
A 1-Hour Resuscitation Bundle for Prehospital Management of Septic Shock.
This multicenter, open-label, cluster-randomized study assessed whether starting a 1-hour resuscitation bundle in the prehospital setting affected 28-day mortality among adults with suspected septic shock managed by…
Managing HIV in the extreme: Viral load and drug monitoring in a patient with BMI > 60 on long-acting cabotegravir/rilpivirine therapy.
A morbidly obese patient with a BMI of 62 kg/m² and a history of poor adherence to oral antiretroviral therapy presented with unsuppressed HIV viral load.
Viral Dynamic Model-Informed Dose Selection of Mosnodenvir Prophylaxis against DENV-3 in a Controlled Human Infection Model.
This Phase IIa controlled human infection model study evaluated mosnodenvir prophylaxis against DENV-3 and used combined population pharmacokinetic and viral dynamic modelling to inform dose selection.
Hepatitis B among hospital nurses worldwide: a meta-analysis of seroprevalence studies.
This meta-analysis assessed the global seroprevalence of hepatitis B virus (HBV) among hospital nurses, analyzing data from 46 studies involving 11,524 nurses.
A rare case of cytomegalovirus mucositis resembling an immune-related adverse event during treatment with nivolumab and ipilimumab.
A 79-year-old man with malignant melanoma of the sphenoid sinus was treated with nivolumab and ipilimumab. He developed immune-related colitis, treated with corticosteroids and infliximab.
Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) carriage among rehabilitation facilities for patients at admission: a systematic review and meta-analysis.
This systematic review and meta-analysis examined risk factors for methicillin-resistant Staphylococcus aureus (MRSA) carriage at admission to rehabilitation facilities.
Safety and immunogenicity of one or two doses of the rVSVΔG-ZEBOV-GP Ebola virus vaccine in adults and adolescents living with HIV: a phase 2, multicentre, double-blind, randomised, placebo-controlled trial.
This phase 2, multicentre, double-blind, randomised, placebo-controlled trial evaluated the safety and immunogenicity of the rVSVΔG-ZEBOV-GP Ebola vaccine in 251 adults and adolescents living with HIV.
A case of esophageal perforation associated with pharyngotonsillitis and Streptococcus anginosus group infection.
A previously healthy 60-year-old man developed progressive right-sided chest pain after pharyngotonsillitis. Although initial chest radiography was unremarkable, computed tomography after clinical deterioration showed…
Acute-on-chronic liver failure following pneumonia in an elderly woman with metabolic dysfunction-associated steatotic liver cirrhosis.
A woman in her 80s with cirrhosis associated with metabolic dysfunction-associated steatotic liver disease developed prolonged acute-on-chronic liver failure (ACLF) triggered by pneumonia.
The effect of metformin on the pharmacokinetics of rifampicin, isoniazid, and pyrazinamide in adults with tuberculosis.
This randomized controlled trial investigated the impact of metformin on the pharmacokinetics of rifampicin, isoniazid, and pyrazinamide in HIV/TB-coinfected adults without diabetes.
Persistent non-viable Plasmodium falciparum parasitemia mimicking artesunate treatment failure and unmasking functional hyposplenism.
A 40-year-old woman was admitted with severe Plasmodium falciparum malaria. Although she improved clinically under intravenous artesunate, parasitemia unexpectedly increased.
Effects of a community-based intervention bundle on household transmission of extended spectrum β-lactamase-producing Escherichia coli in rural Burkina Faso to target community-level drivers of antimicrobial resistance in sub-Saharan Africa: a cluster-randomised trial.
This cluster-randomised controlled trial in rural Burkina Faso evaluated a community-based intervention aimed at reducing household transmission of extended spectrum β-lactamase-producing Escherichia coli (ESBL-E).
Secondary Hemophagocytic Lymphohistiocytosis Triggered by Mixed Plasmodium spp. and SARS-CoV-2 Coinfection.
A patient with mixed Plasmodium vivax and P. falciparum malaria acquired in Mato Grosso, Brazil, and concomitant SARS-CoV-2 infection presented in nonendemic Macaé with high fever and pancytopenia.
Global Bacterial Spectrum, Diagnostic Culture Yield, and Microbiology-Related Mortality Risk in Infective Native Aortic Aneurysm: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis synthesized the bacterial spectrum, culture yield, concurrent infections, and microbiology-related mortality in infective native aortic aneurysm (INAA).
Heterologous prime-boost vaccination against H5 avian influenza: Safety and immunogenicity of a MF59-adjuvanted, cell-culture derived H5N6 vaccine.
This phase II randomized controlled trial evaluated the safety and immunogenicity of an MF59-adjuvanted, cell culture-derived H5N6 vaccine in adults previously primed with an H5N1 vaccine.
Interventions to improve viral suppression and adherence to antiretroviral therapy among people living with HIV: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated adherence interventions for antiretroviral therapy among people living with HIV in low- and middle-income countries.
A systematic review of knowledge, attitudes, and behaviour towards Japanese encephalitis vaccination.
This systematic review examined knowledge, attitudes, and behaviors (KABs) regarding Japanese Encephalitis (JE) vaccination across 26 studies, primarily in endemic countries.
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