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2000 articles
November 202624
A rare injury combination: Hawkins type I talar neck fracture, Jones fracture, and calcaneal avulsion fracture accompanying a bimalleolar ankle fracture.
A patient with a bimalleolar ankle fracture also had a Jones fracture, a Hawkins type I talar neck fracture, and a calcaneal avulsion fracture.
Transcranial Pulse Stimulation in Parkinson's Disease: A Systematic Review.
This systematic review assessed clinical, neurophysiological, imaging, and safety outcomes of transcranial pulse stimulation (TPS) in adults with idiopathic Parkinson’s disease.
Clindamycin and bacterial load reduction as prophylaxis for surgical site infection after below-knee flap and graft procedures.
This randomised controlled trial evaluated clindamycin prophylaxis and preoperative chlorhexidine washing in consecutive patients undergoing below-knee flap or graft procedures.
Do People With Tophaceous Gout Require More Allopurinol for Good Clinical Outcomes? Analysis of 2 Randomized Controlled Trials of Allopurinol Dose Escalation.
This analysis of individual participant data from two randomized allopurinol dose-escalation trials compared outcomes in people with gout with and without baseline tophi.
Phase 1 Evaluation of the Pharmacokinetics of Sevasemten (EDG-5506) for Potential Food Effect and Drug-Drug Interaction With a CYP3A4 Moderate Inhibitor.
This Phase 1, open-label, parallel study assessed the pharmacokinetics of sevasemten in healthy subjects across three cohorts: sevasemten alone while fasted, with verapamil, and after a high-fat meal.
Sleep Management and Recovery After TBI in Kids (SMART-Kids): Pilot Trial Using Melatonin.
This pilot randomized, double-blinded, placebo-controlled trial assessed early melatonin plus sleep education in children aged over 6 to 18 years hospitalized after traumatic brain injury (TBI).
Green Vaginal Discharge in a Late-Preterm Neonate With Massive Ascites.
A late-preterm girl developed abdominal distension and respiratory distress shortly after birth, with anemia, coagulopathy, and massive ascites containing internal debris on ultrasonography.
Effects of Multicomponent Training on Body Composition and Cardiorespiratory Fitness in Adults With Type 2 Diabetes: A Randomized Controlled Trial.
This randomized controlled trial assessed 14 weeks of small-sided soccer training in adults aged 40–70 years with type 2 diabetes.
Anti-Contactin-1 Nodopathy Presenting With Dysphagia and Nephrotic Syndrome: Remarkable Neurological and Renal Recovery Following Early B-Cell-Targeted Therapy.
A 77-year-old man with diabetes and pre-existing heavy proteinuria developed rapidly progressive distal numbness, weakness, sensory ataxia, mild dysphagia, and functional decline.
An Infant With Extreme Hypernatremia Treated With Peritoneal Dialysis.
A 34-day-old, 3.6-kg male infant developed serum sodium >200 mmol/L and multiple organ dysfunction after accidental salt poisoning.
Therapeutic Horseback Riding for Youth With Autism and Psychiatric Comorbidities: A Randomized Trial.
This multisite randomized controlled trial evaluated equine-assisted activities in youth aged 6–16 years with autism and psychiatric comorbidity.
Phase 2 Trial of 89 Zr-Deferoxamine-Daratumumab for CD38-targeted Immuno-PET/CT Detection of Multiple Myeloma.
This prospective phase 2 trial compared CD38-targeted 89Zr-DFO-daratumumab immuno-PET/CT with standard-of-care 18F-FDG PET/CT in 60 participants with multiple myeloma.
Pump-Predicted Ciprofol Ce50 for Suppressing the Cardiovascular Response to Tracheal Intubation During Fixed Sufentanil-Esketamine Induction: An Age-Stratified Dixon Up-and-Down Study.
To estimate the ciprofol pump-predicted effect-site target concentration associated with a 50% probability of suppressing the cardiovascular response to tracheal intubation (Ce50) during fixed sufentanil-esketamine…
Added Value of Preoperative Contrast Enhanced Mammography in Staging of Malignant Breast Lesions (PROCEM): A Randomized Controlled Trial.
This prospective, multicenter randomized controlled trial evaluated whether preoperative contrast-enhanced mammography (CEM) adds value to standard imaging for staging early-stage breast cancer in women eligible for…
Six-Month Music Practice Versus Psychomotor Interventions in Mild Cognitive Impairment: Behavioral and Hippocampal Outcomes.
This pilot randomized controlled intervention study compared six months of intensive musical instrument training with psychomotor interventions in people with mild cognitive impairment (MCI), using matched healthy…
The Effect of Implementing Orem's Self-Care Model on Balance and Fatigue in Patients With Diabetic Neuropathy: A Clinical Trial.
This randomized clinical trial evaluated Orem’s self-care model in 70 patients with diabetic neuropathy recruited by convenience sampling at one clinic.
Peptides for Hair Growth and Treatment of Hair Loss and Alopecia: A Systematic Review.
This systematic review assessed clinical trials of peptide-containing therapies for hair loss in humans. Searches of PubMed, Embase, and the Cochrane Library identified 981 studies, of which 14 met the inclusion…
Fetoscopic Treatment of Twin-to-Twin Transfusion Syndrome After Spontaneous Preoperative Preterm Premature Rupture of the Membranes.
A 23-week monochorionic-diamniotic twin pregnancy was complicated by Stage II twin-to-twin transfusion syndrome (TTTS), followed by spontaneous preoperative preterm premature rupture of the membranes (PPROM).
A Moisturizer With Centella asiatica and Mandelic Acid Reduces Bruising and Speeds Recovery in Mature Skin.
This 12-week multicenter, randomized, blinded, in-use study evaluated a moisturizer containing Centella asiatica and mandelic acid in men and women aged 40 to 60 years with fragile, bruise-prone skin.
Short-Term Pain Outcomes of Trigger Point Injection Versus Dry Needling for Acute Myofascial Low Back Pain in the Emergency Department: A Prospective Randomized Comparative Study.
This prospective randomized comparative study evaluated trigger point injection versus dry needling for acute myofascial low back pain in emergency department patients.
Transformation to Small-Cell Lung Carcinoma and Then to Sarcomatoid Carcinoma in an EGFR-Mutant Lung Adenocarcinoma Patient During Systemic Therapy: A Case Report.
A patient with EGFR-mutant lung adenocarcinoma developed resistance to osimertinib with transformation to combined small-cell lung carcinoma.
Streptozotocin-based chemotherapy in advanced PanNETs: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed objective response and progression-free survival with streptozotocin (STZ)-containing chemotherapy in advanced pancreatic neuroendocrine tumours.
Aberrant Internal Carotid Artery: A Rare Cause of Unfitness Revealed During Admission Audiometry.
A 23-year-old woman undergoing medical assessment for army enlistment was found on audiometry to have unilateral conductive hearing loss. Otoscopy showed a pale red, pulsatile middle-ear mass anterior to the umbo.
Airway occlusions to measure inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation.
This multicenter randomized study assessed whether airway occlusion maneuvers can estimate inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation (NIV).
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