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1320 articles
September 202624
Occlusion site and outcomes in intra-arterial tenecteplase after successful endovascular therapy: a secondary analysis of the ANGEL-TNK trial.
This secondary analysis of the ANGEL-TNK trial evaluated the efficacy of intra-arterial tenecteplase in patients with large vessel occlusion (LVO) stroke, focusing on occlusion sites (internal carotid artery vs.
Minor role of endogenous opioids for acute pain regulation in humans: a systematic review and meta-analysis of placebo-controlled antagonist studies.
This systematic review and meta-analysis examined whether blocking opioid receptors increases pain in healthy volunteers undergoing peripheral pain testing.
Improvement of post-COVID-19 vaccination dysautonomia with GLP-1 receptor agonist.
A 42-year-old woman developed vasovagal syncope (VVS) and neuropathic leg pain after COVID-19 mRNA vaccination. Following semaglutide treatment, her COMPASS-31 score decreased by 44% and her Orthostatic Hypotension…
Intravitreal Onchocerca sp. With Concomitant Cerebral MRI Lesion: A Case Report.
A 24-year-old man from Jakarta presented with blurred vision, floaters, ocular discomfort, and headaches, unresponsive to uveitis treatment.
Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers.
This randomized controlled trial investigated the relationship between matrix metalloproteinase-9 (MMP-9) and CX3CL1 in cerebrospinal fluid biomarkers for amyloid and tau in cognitively unimpaired APOE ε4 carriers…
Pharmacokinetics of Loading Dose Vigabatrin Administered via Enteral Tube in Participants With Post-Anoxic Status Epilepticus.
This study investigated the pharmacokinetics of loading dose vigabatrin in comatose adults with post-anoxic status epilepticus (PASE) as part of an open-label feasibility trial.
Recognizing genetic association between Lhermitte-Duclos Disease and Autism Spectrum Disorder in PTEN-related patients: a case report and literature comprehension.
A mother diagnosed with Lhermitte-Duclos disease (LDD) associated with PTEN Hamartoma Tumor Syndrome (PHTS) presented alongside her 14-year-old daughter, who was diagnosed with autism spectrum disorder (ASD).
When thrombus meets intracranial dissection: a tricky decision for intravenous thrombolysis.
A 34-year-old male presented with sudden neurological symptoms. Initial NCCT showed a hyperdense enlargement of the left V4 vertebral artery, and CTA indicated a focal dissection with thrombus.
Maternal disease control and pregnancy outcomes with anti-CD20 therapy versus natalizumab in multiple sclerosis: a systematic review.
This systematic review evaluated the effectiveness and safety of anti-CD20 therapy versus natalizumab in pregnant women with multiple sclerosis.
The role of artificial intelligence in the diagnosis and prognosis of traumatic brain injury based on brain CT scans: a systematic review.
This systematic review evaluated the role of artificial intelligence (AI) in diagnosing and predicting outcomes of traumatic brain injury (TBI) using brain CT scans.
Hyperbaric oxygen for the treatment of traumatic incomplete spinal cord injury: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the effects of hyperbaric oxygen therapy on patients with traumatic incomplete spinal cord injury.
Gestational Diabetic Ketoacidosis Complicated by a Probable Postpartum Functional Neurological Disorder Following Severe Preeclampsia and Intrauterine Fetal Demise: A Case Report.
A 28-year-old primigravida presented at 34 weeks and 5 days of gestation with gestational diabetic ketoacidosis, severe preeclampsia, and intrauterine fetal demise.
Effects of ketogenic diet on cognitive impairment in older adults: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of ketogenic diet (KD) on cognitive impairment in older adults, analyzing 12 randomized controlled trials with 707 participants.
Deep brain stimulation outcomes in pediatric drug-resistant epilepsy: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the long-term efficacy and safety of deep brain stimulation (DBS) in 149 pediatric patients with drug-resistant epilepsy (DRE).
Clinical efficacy of non-pharmacological interventions on cognitive improvement in patients with mild to moderate Alzheimer's disease: A systematic review and Bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis compared non-pharmacological interventions for cognitive outcomes in people with mild-to-moderate Alzheimer’s disease.
Clinical Reasoning: A 59-Year-Old Man With Delayed Electric Shock-Like Sensations After a Fall.
A 59-year-old man experienced delayed electric shock-like sensations after a fall, occurring 3-4 weeks post-injury. Initially, he had transient global sensory loss, headache, and neck pain, followed by bilateral upper…
Extending the Treatment Window for Intravenous Thrombolysis in Acute Ischemic Stroke: An Updated Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of intravenous thrombolysis (IVT) administered beyond 4.5 hours in patients selected by imaging.
Subarachnoid haemorrhage associated with septic cavernous sinus thrombosis secondary to odontogenic maxillary sinusitis.
A man in his 50s presented with visual loss, altered consciousness, and shock due to septic cavernous sinus thrombosis from odontogenic maxillary sinusitis, complicated by non-aneurysmal subarachnoid hemorrhage.
Motor Improvements Following Non-Invasive Brain Stimulation with kTMP: A Case Study of Cerebellar Stroke.
A 78-year-old patient with cerebellar ataxia due to a hemorrhagic stroke received amplitude-modulated kilohertz transcranial magnetic perturbation (AM-kTMP) targeting the cerebellar vermis and paravermis.
Reversible exacerbation of parkinsonism during epirubicin-cyclophosphamide chemotherapy in a patient with PTEN hamartoma tumor syndrome and young-onset Parkinson's disease.
A patient with a germline PTEN variant and young-onset Parkinson's disease developed severe exacerbations of parkinsonism during epirubicin-cyclophosphamide chemotherapy for bilateral breast cancer.
Efficacy of efgartigimod in the treatment of autoimmune encephalitis: a systematic review.
Autoimmune encephalitis (AE) encompasses a group of inflammatory disorders of the brain parenchyma mediated by autoimmune mechanisms.
A case report on the co-presentation of pituitary abscess and POEMS-like syndrome.
A patient presented with headache, impaired consciousness, and fever, leading to a diagnosis of pituitary abscess and suspected POEMS-like syndrome.
Disproportionate bulbar dysfunction following small corona radiata infarction in vascular parkinsonism: A case report.
A 75-year-old woman with vascular parkinsonism presented with acute dysarthria, severe dysphagia necessitating nasogastric feeding, and significant gait instability.
Efgartigimod as adjunctive therapy for immunotherapy-dependent autoimmune diencephalitis: A case report.
A middle-aged male presented with acute symptoms of autoimmune diencephalitis, including headache, fever, seizures, and impaired consciousness, lasting over three months.
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