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1003 articles
August 202624
The Brief Case: Acute Gangrenous Appendicitis with Incidental Schistosoma Eggs in a Malian Migrant.
A 28-year-old migrant from Mali presented with 24 hours of right lower abdominal pain, anorexia, and low-grade fever. Examination, inflammatory markers, and ultrasound supported acute appendicitis.
From Suppurative Inflammation to Fibrotic Remodeling in Cutaneous Nocardiopsis Infection.
A 77-year-old woman with hypertension and diabetes presented with ulcerated purplish-red nodules on her lower extremities, present for 3 months. Biopsy showed infectious granulomas composed predominantly of neutrophils.
Fecal filtrate transplantation as salvage therapy for fulminant Clostridioides difficile infection in adult hematological patients during chemotherapy-induced aplasia: a pilot experience.
Fulminant Clostridioides difficile infection (CDI) in patients with hematologic malignancies during chemotherapy-induced aplasia carries high mortality and limited treatment options.
Global antibiotic consumption patterns through the lens of the WHO AWaRe framework: An umbrella review.
This umbrella review assessed global antibiotic consumption patterns through the WHO AWaRe framework, analyzing data from 20 systematic reviews and meta-analyses.
Adjunctive Varicella-Zoster Virus-Specific Immunoglobulin for Complicated Varicella-Zoster Virus Infection in Kidney Transplant Recipients: Case Series.
Three kidney transplant recipients presented with severe varicella-zoster virus (VZV) infections, including disseminated primary infection and herpes zoster with ocular involvement.
"Since I got the education, I feel like a kind of warrior": a qualitative study of participant perspectives and preferences about Sauti ya Vijana, a mental health intervention for young people with HIV in Tanzania.
This qualitative study explored how young people with HIV in Tanzania experienced Sauti ya Vijana (SYV), a co-created, peer-led group mental health intervention, and what they preferred about it.
A Case of Adult-onset Presumed Congenital Syphilitic Keratitis: A Multidisciplinary Management Approach.
A 28-year-old man had an 11-year history of progressive bilateral redness, tearing, and visual decline. Examination showed bilateral interstitial keratitis; treponemal serology was positive and nontreponemal serology…
Systematic review of the mutations in the active antigenic site Ø of the prefusion F protein of the Respiratory Syncytial Virus (RSV) following the implementation of monoclonal antibody prophylaxis.
This systematic review analyzed mutations in the antigenic site Ø of the RSV prefusion F protein following the introduction of the monoclonal antibody nirsevimab in children with confirmed RSV infections.
LIMIT Trial: Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema pallidum Treatment.
The LIMIT trial was a double-blinded, randomized, placebo-controlled study comparing 0.5 mL of 1% lidocaine with 0.5 mL saline added to intramuscular benzathine penicillin G in adults treated for syphilis at one…
Diagnostic performance of panfungal PCR on tissue specimens for the diagnosis of invasive fungal diseases: a systematic review and meta-analysis of the Fungal PCR Initiative (FPCRI).
This systematic review and meta-analysis evaluated the diagnostic performance of panfungal PCR on tissue specimens for invasive fungal diseases.
Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17-36.
This phase I clinical trial evaluated the immunogenicity of 20 µg AAV2-like particles displaying HPV L2 residues in 20 healthy subjects.
Risk of post-acute symptoms and conditions after SARS-CoV-2 compared with other respiratory viral infections: a systematic review and meta-analysis.
This systematic review and meta-analysis compared persistent symptoms and conditions in adults after SARS-CoV-2 infection with those following other acute respiratory viral infections.
Pathways of onward HIV disclosure in relationships among young people living with vertically acquired HIV receiving antiretroviral therapy: A qualitative analysis from the BREATHER Plus trial, South Africa.
This qualitative analysis from the BREATHER Plus trial explored how young people living with vertically acquired HIV in KwaZulu-Natal, South Africa, manage onward disclosure in relationships.
MIC-based tuberculosis drug susceptibility testing using Sensititre MYCOTB: a diagnostic accuracy meta-analysis.
This meta-analysis evaluated the diagnostic performance of Sensititre MYCOTB for drug susceptibility testing in multidrug-resistant (MDR) and pre-extensively drug-resistant tuberculosis (pre-XDR TB).
Beyond One Gene: a systematic review of layered evidence for antileishmanial resistance in Leishmania infantum.
This systematic review examined genetic evidence for antileishmanial resistance in Leishmania infantum, focusing on 29 studies.
Stepwise low-pressure VAC for deep sternal infection in a 2.8-kg infant.
A 2-month-old, 2.8-kg boy developed a deep sternal wound infection after repair of an atrial septal defect, ventricular septal defect, and patent ductus arteriosus.
Global prevalence of tigecycline-resistant foodborne Enterobacterales along the food chain: A meta-analysis.
This meta-analysis evaluated the global prevalence of tigecycline-resistant Enterobacterales in food and food-producing animals, analyzing 104 studies. The overall resistance rate was found to be 4.36%, with E.
Pharmacokinetics and Tolerability of Fexinidazole in Subjects with Hepatic Impairment.
This Phase I multicenter trial evaluated the pharmacokinetics of fexinidazole in 21 participants with mild and moderate hepatic impairment (HI) compared to healthy controls.
Disseminated sporotrichosis masquerading as tuberculosis in a patient without overt immunodeficiency: challenges in tuberculosis-endemic area.
A 78-year-old man presented with progressive ulcerative skin lesions, pulmonary symptoms, and osteomyelitis over six months.
Voriconazole versus itraconazole for antifungal prophylaxis in patients with graft-versus-host disease: A prospective randomized trial.
This randomized phase II selection trial compared 60 days of voriconazole (VRCZ) with itraconazole (ITCZ) prophylaxis in allogeneic HCT recipients with grade II–IV acute GVHD or chronic GVHD requiring systemic…
Post-Acute Sequelae of Non-COVID-19 Respiratory Viral Infections: A Systematic Review.
This systematic review examined observational evidence on persistent or new health outcomes at least 4 weeks after non-COVID respiratory viral infections in adults.
Multisystem Inflammatory Syndrome Therapies in Children: A Comparative Effectiveness Trial.
This two-hospital comparative effectiveness trial evaluated infliximab, methylprednisolone, and anakinra in children with intravenous immunoglobulin (IVIG)-resistant multisystem inflammatory syndrome (MIS-C).
Cutibacterium avidum caused a liver abscess after transarterial chemoembolization for hepatocellular carcinoma.
An 83-year-old man developed a liver abscess following transarterial chemoembolization for recurrent hepatocellular carcinoma, presenting with fever 10 days post-procedure.
Domiciliary colonization by Panstrongylus geniculatus associated with human blood meal in Salto do Itararé, Paraná State, Brazil.
Despite the control of Triatoma infestans in Brazil, other vectors remain implicated in the transmission of Chagas disease, making the maintenance of municipal entomological surveillance and health education actions…
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