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1357 articles

October 202624

Clinical ResearchInfectious Diseases

Second-hand smoke exposure linked to TB infection or disease in children/adolescents: systematic review and meta-analysis.

This PROSPERO-registered systematic review and meta-analysis examined observational evidence on household second-hand smoke (SHS) exposure and tuberculosis (TB) outcomes in children and adolescents aged 0–18 years in…

Int J Tuberc Lung DisOct 30, 2026Read summary
Clinical ResearchNeurologyOpen access

First-in-Human Phase 1b/2a Trial Shows Safety with MEK 1/2 Inhibitor EDV2209 as A Novel Treatment for Spontaneous Subarachnoid Hemorrhage.

The STOP-DCI first-in-human Phase 1b/2a interventional, randomized, double-blind, placebo-controlled trial evaluated intracerebroventricular EDV2209, a MEK 1/2 inhibitor, in patients with severe spontaneous subarachnoid…

Transl Stroke ResOct 30, 2026Read summary
Clinical ResearchCardiologyOpen access

The effect of early rehabilitation nursing on the recovery of cardiac function in patients with acute myocardial infarction.

This prospective randomised controlled trial compared structured early rehabilitation nursing with routine postoperative nursing in patients with acute myocardial infarction treated by percutaneous coronary…

J Health Popul NutrOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Risk factors for Post-COVID-19 Syndrome in patients hospitalized for severe acute respiratory syndrome: systematic review and meta-analysis.

This systematic review and meta-analysis examined factors associated with post-COVID-19 syndrome among patients discharged after hospitalization for severe acute respiratory syndrome.

Cien Saude ColetOct 30, 2026Read summary
Clinical ResearchCardiology

Efficacy of Stellate Ganglion Block for Preventing Postoperative Atrial Fibrillation After Cardiac Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

This single-center, randomized, double-blind, placebo-controlled trial assessed whether preoperative ultrasound-guided right stellate ganglion block (SGB) prevents postoperative atrial fibrillation (POAF) in patients…

J Am Heart AssocOct 30, 2026Read summary
Clinical ResearchNephrology

Post-transplant follow-up for kidney transplant recipients: a systematic review of clinical practice guidelines.

This systematic review compared clinical practice guidelines for post-transplant follow-up of kidney transplant recipients, assessing methodological quality and recommendations for surveillance.

J NephrolOct 30, 2026Read summary
Clinical ResearchPsychiatryOpen access

Dose-Dependent Effect of Crocin on Depressive and Anxiety Symptom Scores: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This GRADE-assessed systematic review and meta-analysis examined dose-response associations between crocin supplementation and depressive and anxiety symptom scores in 14 randomized controlled trials.

Depress AnxietyOct 30, 2026Read summary
Clinical ResearchNeurology

Maternal and Fetal Safety Outcomes of Thrombolytics for Ischemic Stroke in Pregnancy: A Systematic Review and Aggregated Case Series.

This systematic review and Bayesian aggregated case series examined maternal and fetal outcomes after thrombolytic treatment during pregnancy.

NeurologyOct 30, 2026Read summary
Clinical ResearchCardiology

Incidence of Intensive Care Unit Delirium After Heart Surgery: A Feasibility Study of a Forest Environment Intervention.

This randomized feasibility study evaluated forest-environment and light-exposure interventions, compared with standard care, in adults undergoing elective cardiac surgery at a tertiary ICU in Austria.

Nurs Crit CareOct 30, 2026Read summary
Clinical ResearchPsychiatry

Effects of psilocybin with psychological support on anhedonia in treatment-resistant depression: A randomized controlled pilot trial.

This randomized, double-blind, placebo-controlled pilot trial assessed psilocybin with psychological support for anhedonia in 20 participants with treatment-resistant major depressive disorder.

J Affect DisordOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Factors associated with missed video directly observed therapy sessions among persons with TB.

This secondary analysis of the DOT Selfie randomised controlled trial in Uganda examined factors associated with missed video directly observed therapy (VDOT) submissions during TB treatment.

Int J Tuberc Lung DisOct 30, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Visual rigid laryngoscope versus Macintosh laryngoscope using low-dose relaxants in thyroid surgery.

This single-centre randomized controlled trial compared visual rigid laryngoscopy (VRL) with Macintosh laryngoscopy for tracheal intubation in patients undergoing elective thyroid surgery with intraoperative…

PeerJOct 30, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Auricular point acupressure for chemotherapy-induced peripheral neuropathy: a randomized controlled trial.

This pragmatic randomized controlled trial evaluated auricular point acupressure (APA) for chemotherapy-induced peripheral neuropathy in 227 cancer survivors, comparing in-person delivery, video-guided self-placement…

Support Care CancerOct 30, 2026Read summary
Clinical ResearchCardiology

Slow Flow/No-Reflow After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Meta-Analysis.

This meta-analysis synthesized clinical, laboratory, angiographic, and procedural factors associated with coronary slow flow/no-reflow after primary PCI for STEMI.

J Vis ExpOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

How do adult migrants with active TB adhere to care in high-income countries? A systematic review.

This systematic review examined adherence to the TB care process among adult migrants with active TB in high-income countries.

Int J Tuberc Lung DisOct 30, 2026Read summary
Clinical ResearchPulmonologyOpen access

The effect of propolis oral care on oral mucositis in intensive care patients with chronic obstructive pulmonary disease: a randomized controlled trial.

This randomized controlled trial evaluated whether adding propolis gargle to standard oral care prevented oral mucositis in 60 critically ill patients with chronic obstructive pulmonary disease.

Rev Assoc Med Bras (1992)Oct 30, 2026Read summary
Clinical ResearchNephrology

Efficacy and Safety of Nafamostat Mesilate Injection in Patients Receiving Continuous Renal Replacement Therapy: A Meta-Analysis.

This meta-analysis assessed the efficacy and safety of nafamostat mesilate injection versus no anticoagulation in patients receiving continuous renal replacement therapy (CRRT).

J Vis ExpOct 30, 2026Read summary
Clinical ResearchDermatology

Integrated Traditional Chinese Medicine, Mili-Fire Needle, and Light-Emitting Diode Phototherapy for Cystic Acne and Post-Acne Sequelae.

This single-center, parallel-group randomized clinical study compared an integrated traditional Chinese medicine regimen, mili-fire needle therapy, and red-blue LED phototherapy with isotretinoin plus the same…

J Vis ExpOct 30, 2026Read summary
Clinical ResearchGastroenterologyOpen access

MLH1 AND MSH2 PROTEIN EXPRESSION LOSS AND MICROSATELLITE INSTABILITY IN COLORECTAL ADENOMAS OF PATIENTS WITH LYNCH SYNDROME: A SYSTEMATIC REVIEW AND META-ANALYSIS.

This systematic review and meta-analysis assessed the relationship between microsatellite instability (MSI) and loss of MLH1 or MSH2 expression in colorectal adenomas from people with Lynch syndrome.

Arq GastroenterolOct 30, 2026Read summary
Clinical ResearchGeriatrics

The Effects of Force-Velocity Profile-Based Load Prescription on Muscle Power and Functional Performance in Velocity-Deficient Older Adults.

This 12-week randomized controlled trial compared force–velocity profile-guided resistance-training loads in adults aged 65 years or older with a velocity deficit.

Scand J Med Sci SportsOct 30, 2026Read summary
Clinical ResearchOncology (Medical)

Phase 1 Study of Safety and PK With A Combination of Omeprazole and Trimetazidine for Fatty Acid Oxidation Inhibition in Patients With Advanced Solid Tumors.

This Phase I, open-label, 3 + 3 dose-escalation study assessed safety, tolerability, pharmacokinetics, and preliminary antitumor activity of once-daily oral omeprazole plus trimetazidine, two fatty acid oxidation…

Clin Transl SciOct 30, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Survival Outcomes in Metastatic Colorectal Cancer Patients with BRAF Mutations Undergoing Targeted Chemotherapy: A Reconstructed Individual Patient Data Meta-Analysis of Randomized Controlled Trials.

This reconstructed individual patient-data meta-analysis of 18 randomized controlled trials examined survival outcomes across targeted treatment classes in BRAF V600E-mutant metastatic colorectal cancer.

J Gastrointest CancerOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Reducing Central Line-Associated Bloodstream Infections in ICUs: A Systematic Review of Barriers and Facilitators and Intervention Measures.

This PRISMA-guided systematic review examined barriers and facilitators to implementing central line-associated bloodstream infection (CLABSI) prevention among ICU healthcare workers.

Nurs Crit CareOct 30, 2026Read summary
Clinical ResearchNephrology

Association of Helicobacter pylori eradication with proteinuria reduction and kidney outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.

J NephrolOct 30, 2026Read summary

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