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557 articles

May 202617

Clinical ResearchOncology (Medical)Open access

Novel multiplex immunofluorescence-based tumor inflammation score provides apparent predictive biomarker in a phase I/II study of pembrolizumab with gemcitabine in patients with previously-treated advanced non-small cell lung cancer (NSCLC).

This phase I/II clinical trial evaluated the safety and efficacy of pembrolizumab combined with gemcitabine in 16 patients with previously-treated advanced non-small cell lung cancer (NSCLC).

OncoimmunologyMay 13, 2026Read summary
Clinical ResearchPulmonology

Mitomycin C in the Endoscopic Treatment of Airway Stenosis: A Systematic Review and a Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy of adjuvant mitomycin C (MMC) in the endoscopic treatment of airway stenosis, involving 358 patients with a median age of 48 years.

Ann Otol Rhinol LaryngolMay 13, 2026Read summary
Case ReportInfectious Diseases

Acute pulmonary histoplasmosis in a Belgian traveller returning from Suriname diagnosed with NGS: a case report.

A 48-year-old Belgian woman presented with fever, dry cough, and dyspnoea after a trip to Suriname. Imaging revealed nodular masses and lymphadenopathy in the lungs.

Diagn Microbiol Infect DisMay 12, 2026Read case
Clinical ResearchPathology (Anatomic & Clinical)

Diagnosis of the Novel IASLC Grading System Using Intraoperative Frozen Section (ECTOP-1014): A Prospective, Multicenter Clinical Trial.

This prospective, multicenter clinical trial evaluated the accuracy of intraoperative frozen section in diagnosing IASLC grades in early-stage lung adenocarcinoma.

Ann Thorac SurgMay 12, 2026Read summary
Clinical ResearchPulmonology

Compliance and Genetic Variability Are Determinants of the Success of l-Arginine/l-Citrulline Supplementation in High Altitude-A Pilot Study.

This pilot randomised controlled trial tested whether l-arginine/l-citrulline (A/C) supplementation limited the rise in pulmonary arterial pressure (PAP) during chronic intermittent hypoxia.

High Alt Med BiolMay 12, 2026Read summary
Clinical ResearchAllergy & Immunology

Predictors of Retention and Sustained Engagement With a 12-Month Asthma Self-Management App in Underserved Adults.

This randomized controlled trial examined predictors of dropout and sustained use of ASTHMAXcel PRO over 12 months among adults with asthma receiving daily controller medication at three Bronx primary care clinics.

Respir CareMay 11, 2026Read summary
Clinical ResearchPulmonology

The Association of Sarcopenic Obesity With Respiratory Function Outcomes in Adults: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined observational studies of adults with and without sarcopenic obesity and their respiratory function.

Obes RevMay 8, 2026Read summary
Clinical ResearchPulmonologyOpen access

Fibroblast activation protein-targeted molecular imaging in interstitial lung disease: a systematic review.

This systematic review evaluates the role of fibroblast activation protein (FAP)-targeted imaging in interstitial lung disease (ILD).

Ann Nucl MedMay 7, 2026Read summary
Clinical ResearchPulmonology

Association between nocturnal asthma, symptom severity, and clinical outcomes: a systematic review.

This systematic review examined the relationship between nocturnal asthma and symptom severity, pulmonary function, and clinical outcomes in both adults and children.

J AsthmaMay 7, 2026Read summary
Case ReportOncology (Medical)Open access

Hyalinizing Clear Cell Carcinoma of the Lung With Uncommon Distant Cutaneous Metastasis and Aggressive Clinical Course.

A patient presented with primary lung hyalinizing clear cell carcinoma (PLHCCC) characterized by tumor lobules with pale cytoplasm and a mixed stroma.

J Cutan PatholMay 5, 2026Read case
Clinical ResearchPulmonology

Prevalence and associated factors of dysphagia in chronic obstructive pulmonary disease patients: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prevalence and associated factors of dysphagia in patients with chronic obstructive pulmonary disease (COPD).

Heart LungMay 4, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Association between the systemic inflammation response index and prognosis in lung cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic value of the systemic inflammation response index (SIRI) in lung cancer patients.

Clin Transl OncolMay 4, 2026Read summary
Clinical ResearchPulmonology

Effects of continuous positive airway pressure therapy on depression and anxiety in patients with obstructive sleep apnea with and without coronary heart disease.

This randomized controlled trial examined the effects of continuous positive airway pressure (CPAP) therapy on anxiety and depression in 72 patients with obstructive sleep apnea (OSA), both with and without coronary…

Heart LungMay 2, 2026Read summary
Clinical ResearchPulmonology

Association between fluid balance and weaning outcomes in patients with mechanical ventilation: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between fluid balance and weaning outcomes in patients on mechanical ventilation, analyzing 26 studies with 13,665 patients.

Heart LungMay 2, 2026Read summary
Clinical ResearchPediatrics

Effects of Endotracheal Suctioning With Expiratory Pause in Infants.

This randomized controlled trial evaluated the effectiveness of closed endotracheal suctioning with an expiratory pause in infants on invasive mechanical ventilation.

Respir CareMay 2, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

The effect of bracing on pulmonary function in adolescent idiopathic scoliosis: a systematic review with meta-analysis.

This systematic review and meta-analysis examined controlled clinical trials of bracing and pulmonary function in adolescents with idiopathic scoliosis. Fourteen studies involving 548 participants were included.

Spine DeformMay 2, 2026Read summary
Clinical ResearchAnesthesiology

Automated control of inspired oxygen in mechanically ventilated trauma and acute care surgery patients: A randomized controlled trial.

This randomized controlled trial evaluated the effectiveness of automated physiologic closed-loop control (PCLC) of inspired oxygen fraction (FIO2) compared to manual control (MC) in mechanically ventilated trauma and…

J Trauma Acute Care SurgMay 1, 2026Read summary

April 20267

Case ReportOncology (Medical)

Tuberculosis versus immune-related bronchiolitis under immune checkpoint inhibitor - a diagnostic challenge.

A 53-year-old man with metastatic clear-cell renal cell carcinoma developed respiratory symptoms after receiving immune checkpoint inhibitors. Imaging revealed centrilobular nodules, and QuantiFERON testing was positive.

Acta Clin BelgApr 30, 2026Read case
Clinical ResearchPulmonology

Efficacy and safety of nerandomilast in patients with autoimmune disease-related progressive pulmonary fibrosis in the FIBRONEER-ILD trial.

The FIBRONEER-ILD trial evaluated the efficacy and safety of nerandomilast in 325 patients with autoimmune disease-related progressive pulmonary fibrosis.

Ann Rheum DisApr 30, 2026Read summary
Clinical ResearchPulmonology

Comparative efficacy of mind-body exercises for treating chronic obstructive pulmonary disease: a systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the effectiveness of various mind-body exercises in treating chronic obstructive pulmonary disease (COPD) among 3179 participants.

Clin RehabilApr 29, 2026Read summary
Clinical ResearchPulmonology

Efficacy and Safety of Mepolizumab in Eosinophilic COPD: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy and safety of mepolizumab in patients with eosinophilic chronic obstructive pulmonary disease (COPD).

Ann PharmacotherApr 26, 2026Read summary
Clinical ResearchCardiologyOpen access

A systematic review of physical activity guidelines for adults with cardio-respiratory diseases: Stepping towards evidence-based recommendations.

This systematic review evaluated physical activity guidelines for adults with cardio-respiratory diseases, including chronic obstructive pulmonary disease, asthma, and heart failure.

Clin RehabilApr 24, 2026Read summary
Clinical ResearchPulmonology

FILONEX - A prospective, randomized controlled pilot safety study evaluating the addition of hemodiafiltration to EVLP in marginal donor lungs.

The FILONEX trial evaluated the safety and feasibility of adding hemodiafiltration (HDF) to ex vivo lung perfusion (EVLP) in 30 marginal donor lungs.

J Heart Lung TransplantApr 22, 2026Read summary
Clinical ResearchPulmonology

Safety and extrapulmonary effects of elexacaftor-tezacaftor-ivacaftor in people with cystic fibrosis following lung transplantation: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the safety and efficacy of elexacaftor-tezacaftor-ivacaftor in 195 cystic fibrosis patients post-lung transplantation.

Paediatr Respir RevApr 21, 2026Read summary

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