Trending archive
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1003 articles
August 202624
Necrotizing Fasciitis After Cesarean Section: A Case Report.
A 35-year-old primigravida developed fever, raised inflammatory markers, and uterine tenderness on postoperative day 6 after emergency cesarean delivery.
Two Rare Cases of Mesh Infection Due to Mycobacterium abscessus Following Laparoscopic Inguinal Hernia Repair.
Two patients developed delayed groin pain and fluid collections after total extraperitoneal laparoscopic inguinal hernia repair.
Extent-Guided Staged Management of Localized Late-Onset MSSA Sternal Infection after Bilateral Lung Transplantation: A Case Report.
A 38-year-old woman developed methicillin-susceptible Staphylococcus aureus (MSSA) sternal infection with bacteremia seven months after bilateral lung transplantation.
Bivalent RSV Prefusion F Vaccine to Prevent Hospitalizations in Adults.
This randomized controlled trial evaluated the bivalent RSV prefusion F (RSVpreF) vaccine's effectiveness in preventing RSV-related hospitalizations among adults in Denmark and Spain.
Durability of RSV Prefusion F Vaccine Protection across Two RSV Seasons.
This randomized controlled trial evaluated the durability of protection from the RSV prefusion F vaccine (RSVpreF) in adults aged 60 and older across two RSV seasons.
Severe Plasmodium falciparum malaria with marked ADAMTS13 reduction and secondary microangiopathic features: A case report.
A 46-year-old man returning from Nigeria presented with severe Plasmodium falciparum malaria after 11 days of intermittent fever, jaundice, and dark urine.
Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis.
This international, open-label randomized trial compared response-tailored with standard-duration antibiotic therapy in clinically stable adults with left-sided infective endocarditis caused by Staphylococcus aureus…
Autodissemination stations suppress Aedes notoscriptus mosquitoes and reduce Buruli ulcer risk in urban Australia: a randomized controlled field trial.
This randomized controlled trial evaluated the effectiveness of autodissemination mosquito control stations in reducing Aedes notoscriptus populations and Buruli ulcer risk in urban Melbourne, Australia.
Immunomodulation Therapy to Treat Severe Malaria With Multiple Organ Failure.
A 5-year-old girl returning from the Democratic Republic of the Congo presented with fever, shock, 10.9% parasitemia, acute kidney injury, and multiple organ dysfunction.
A multi-center, open-labelled, randomized controlled extended phase III non-inferiority clinical trial to evaluate the immunogenicity and tolerability of poliomyelitis vaccine (Vero cells), inactivated, Sabin strains administered with or without routine infant vaccines.
This multi-center, open-label, randomized controlled trial evaluated the immunogenicity and tolerability of inactivated poliomyelitis vaccine (sIPV) administered with or without routine infant vaccines in 1442 healthy…
Traditional, complementary, and integrative medicine therapies for mild/moderate acute COVID-19: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the effectiveness of Traditional, Complementary, and Integrative Medicine (TCIM) therapies for mild/moderate acute COVID-19 in 18,627 patients across 69 trials.
Malaria Vaccine Rollout in Nigeria: Current Status and Challenges.
This systematic review examined implementation, awareness, acceptance, willingness to pay, and health system readiness for malaria vaccine rollout in Nigeria.
Impact of renal impairment on pharmacokinetics, safety, and tolerability of funobactam, combined with imipenem and cilastatin.
This phase 1, open-label study assessed the pharmacokinetics and safety of a single intravenous dose of funobactam with imipenem and cilastatin in participants across five renal-function categories, including end-stage…
Risk factors for invasive yeast infections in adult patients with hematological malignancies and/or stem cell transplant: systematic literature review and meta-analysis.
This systematic review and meta-analysis examined risk factors for invasive yeast infections (IYI) in adults with hematological malignancies or undergoing hematopoietic stem cell transplantation.
Safety and immunogenicity of an mRNA COVID-19 vaccine administered to adults: A phase 2, randomized, active-controlled trial.
This phase 2, randomized, active-controlled trial evaluated the safety and immunogenicity of two investigational mRNA COVID-19 vaccines in healthy adults aged 18 and older who had completed their primary vaccination…
Secondary Hemophagocytic lymphohistiocytosis in an immunocompetent adult: a case report distinguishing sarcoidosis from histoplasmosis.
A 73-year-old immunocompetent male presented with lethargy and poor oral intake, initially diagnosed with sarcoidosis. Clinical evaluation revealed fever, splenomegaly, pancytopenia, and elevated inflammatory markers.
Prognostic value of the lactate-to-albumin ratio in adult sepsis: An updated systematic review of prognostic evidence.
This systematic review assessed the prognostic value of the lactate-to-albumin ratio (LAR) for mortality in adults with sepsis or septic shock.
Outer membrane vesicles in Pseudomonas aeruginosa pathogenesis: a systematic review of virulence dissemination, immune modulation, and antimicrobial resistance, with perspectives for veterinary and one health practice.
This systematic review examines the role of outer membrane vesicles (OMVs) in Pseudomonas aeruginosa pathogenesis, focusing on their virulence, immune modulation, and antimicrobial resistance.
Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy. Part II: Cephalosporins.
This systematic review evaluated the pharmacokinetics of cephalosporins in pregnant women, analyzing 44 studies. It found that during the second and third trimesters, the volume of distribution and clearance of these…
Giardia duodenalis Infection and Pachymeningitis in a Patient With Agammaglobulinemia.
A 14-year-old patient with X-linked agammaglobulinemia presented with persistent fever, bloody diarrhea, and headache. Chronic giardiasis was identified, and brain MRI showed minimal diffuse dural thickening interpreted…
Effectiveness of Antiseptic and Antibiotic Use to Prevent Central Line-Associated Bloodstream Infections in ICU Patients: A Systematic Review and Narrative Synthesis of Randomized Clinical Trials.
This systematic review evaluated the effectiveness of antiseptics and antibiotics in preventing central line-associated bloodstream infections (CLABSI) in ICU patients.
Butyrylcholinesterase Activity as a Mortality Marker in ICU Patients: An Individual Participant Data Meta-Analysis.
This meta-analysis evaluated the prognostic value of butyrylcholinesterase (BChE) activity for in-hospital mortality in critically ill adults, primarily those with sepsis.
Genetic diversity of clinical Mycobacterium bovis BCG isolates from an immunocompromised patient with BCG infection.
The Bacillus Calmette-Guérin (BCG) vaccine is widely administered to prevent severe tuberculosis but can cause serious adverse events, including disseminated BCGosis, in immunocompromised individuals.
Favorable clinical and microbiological outcomes of a war-associated prosthetic joint infection caused by Klebsiella pneumoniae treated with combined phage-colistin therapy.
A patient with a prosthetic elbow infection due to multidrug-resistant Klebsiella pneumoniae, following a war-related injury, presented after failing multiple antibiotic treatments.
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