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1357 articles
November 202624
Is Exercise Effective at Reducing Pain Catastrophizing in People With Chronic Nonspecific Spinal Pain? A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined whether exercise reduces pain catastrophizing in people with chronic nonspecific spinal pain.
Regimens of vitamin D supplementation for women during pregnancy.
This updated Cochrane systematic review and meta-analysis assessed randomised trials of vitamin D regimens during pregnancy in women without pre-existing conditions or multiple pregnancies.
XR serious games for phantom limb pain, neurofunctional recovery, and prosthetic adoption: a systematic review.
This systematic review synthesized studies of extended-reality serious games for adults with limb amputation, examining phantom limb pain, rehabilitation, embodiment, and prosthesis adoption.
Poly (ADP-ribose) polymerase inhibitors (PARPi) for treating advanced epithelial ovarian cancer.
This Cochrane systematic review and meta-analysis assessed randomised trials of PARP inhibitors (PARPi) in women with newly diagnosed or recurrent epithelial ovarian cancer. It included 24 studies with 8961 participants.
Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.
This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…
Physical Activity in Young Girls With Functional Abdominal Pain Disorders: Findings of a Randomized Controlled Intervention Trial With Dance and Yoga.
This randomized controlled trial assessed daily physical activity and abdominal pain in girls aged 9 to 13 years with functional abdominal pain disorders who participated in an 8-month dance and yoga intervention.
Conservative versus surgical management of traumatic acute subdural hematoma: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared surgical with conservative management of traumatic acute subdural hematoma in adults.
Cutaneous Silent Period-Based Comparison of Dorsal Root Ganglion Pulsed Radiofrequency and Transforaminal Epidural Steroid Injection in Lumbar Radicular Pain: A Randomized Controlled Trial.
This prospective, single-blind randomized controlled trial compared dorsal root ganglion pulsed radiofrequency (DRG-PRF) with transforaminal epidural steroid injection (TFESI) in 36 patients with chronic unilateral…
Postoperative Tumor-Informed Circulating Tumor DNA Status for Molecular Residual Disease Detection After Curative-Intent Resection of Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled observational evidence on postoperative tumor-informed circulating tumor DNA (ctDNA) as a marker of molecular residual disease after curative-intent resection of…
Intimate partner violence against women in Ethiopia: An umbrella review of systematic reviews and meta-analyses.
This umbrella review and random-effects meta-analysis synthesized six systematic reviews and meta-analyses, covering 80 primary studies and 43,785 women in Ethiopia, to estimate intimate partner violence (IPV)…
Efficacy and safety of selective orexin 2 receptor agonists in narcolepsy type 1: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled randomized, double-blind, placebo-controlled trials of oral selective orexin 2 receptor agonists in people with narcolepsy type 1.
Polyamine Dysregulation in Metabolic Dysfunction-associated Steatotic Liver Disease: a Systematic Review of Human Observational Evidence.
This systematic review evaluated human observational evidence linking polyamines with MASLD severity and related hepatic or metabolic outcomes.
Efficacy and safety of middle meningeal artery embolisation for chronic subdural haematoma: a systematic review and meta-analysis of randomised controlled trials.
This PRISMA-compliant systematic review and meta-analysis pooled randomised controlled trials comparing middle meningeal artery embolisation (MMAE)-based treatment with standard management in adults with radiologically…
Digital Health Interventions for Pregnancy- and Childbirth-Related Posttraumatic Stress Disorder Symptoms in Postpartum Women: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled randomized controlled trials of digital health interventions for postpartum women who had experienced pregnancy- or childbirth-related trauma.
Perioperative neurocognitive outcomes after robot-assisted pelvic surgery: a systematic review and meta-analysis of reported proportions, comparative risk and prognostic factors.
This systematic review and meta-analysis examined delirium and cognitive decline after robot-assisted pelvic surgery in adults, including reported proportions, comparative risk, and prognostic factors.
Evaluating the Feasibility, Acceptability, and Preliminary Efficacy of Virtually Delivered Dialectical Behaviour Therapy Skills Groups Among Emerging Adults in India.
This randomized controlled trial assessed the feasibility, acceptability, and preliminary efficacy of an eight-week, video-delivered dialectical behaviour therapy skills group led by student therapists in India.
The Association Between Paternal BMI and Semen Quality in Cohorts Undergoing IUI, IVF and ICSI Fertility Treatments: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined associations between paternal BMI and semen quality in cohorts undergoing intrauterine insemination or assisted reproductive technology.
Effects on Sleep Quality and Bioelectrical Parameters of Cellular Health After Administration of a Plant Protein Supplement Combined with Ashwagandha and Rhodiola: A Randomized Controlled Trial.
This randomized, double-blind, placebo-controlled trial tested 30 days of plant protein combined with ashwagandha and rhodiola in adults aged 35–70 years. Of 100 participants assigned, 61 completed sleep assessments.
Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.
This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…
Time-dependent efficacy of seven pharmacological regimens for ulcer healing and delayed bleeding prevention after gastric endoscopic submucosal dissection: A frequentist network meta-analysis.
This frequentist network meta-analysis compared seven pharmacological regimens for ulcer healing and prevention of delayed bleeding or perforation after gastric endoscopic submucosal dissection.
Loberamisal for Acute Ischemic Stroke: The LAIS Randomized Clinical Trial.
The LAIS trial was a multicenter, double-blind, randomized, placebo-controlled phase 3 study at 32 hospitals in China. It enrolled adults aged 18 to 80 years with acute ischemic stroke, treated within 48 hours, and…
Physiological prehabilitation for patients undergoing cellular therapy in multiple myeloma and lymphoma: a systematic review.
This systematic review examined exercise-based physiological prehabilitation in adults with multiple myeloma or lymphoma before cellular or immune-based therapy.
Commonly experienced acute and cumulative 8-hour sleep loss differentially affect simulated driving during a night-time to early-morning commute: a randomized controlled crossover trial.
This randomized within-subject crossover trial compared simulated driving after normal sleep, four nights with 2 h less sleep per night, and one night without sleep in 20 healthy men.
Effect of pelvic floor reconstruction on postoperative urinary continence after robot-assisted radical prostatectomy: a meta-analysis.
This meta-analysis pooled controlled studies comparing pelvic floor reconstruction (PR) with no reconstruction during robot-assisted radical prostatectomy (RARP).
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