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412 articles
October 202624
Effectiveness of a Ceramide-Based Lamellar Emulsion on Skin Barrier Function in Surgical Nurses: A Randomized Controlled Trial.
This single-center randomized controlled trial assessed whether a ceramide-based lamellar emulsion improved hand skin barrier function in surgical nurses exposed to frequent perioperative hand hygiene.
Secondary Syphilis.
A 46-year-old man presented with two months of progressive, painful visual loss. Examination showed bilateral panuveitis alongside widespread ulcerative skin lesions and alopecia.
Can Photobiomodulation improve healing of category II-III pressure ulcers in frail older adults? A quasi-experimental 24-month follow-up study.
This quasi-experimental study compared adjunctive photobiomodulation with standard care for category II and III pressure ulcers in frail adults aged 70 years or older receiving municipal home healthcare.
Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.
A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.
Cutaneous features of SDR9C7 variants in eight individuals with autosomal recessive nonsyndromic epidermal differentiation disorders.
Eight individuals with SDR9C7 variants and nonsyndromic epidermal differentiation disorders had scaling and erythema, commonly with fine scale, hyperlinear palms, and greater involvement of the extremities, particularly…
The follicular microbiome in hair-follicle-associated inflammatory diseases: a systematic review.
This systematic review qualitatively synthesized culture-independent studies of the bacterial hair-follicle microbiome in inflammatory hair-follicle-associated diseases.
Efficacy and safety of icotrokinra for plaque psoriasis: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed icotrokinra, an oral IL-23 receptor antagonist, in adolescents and adults with moderate-to-severe plaque psoriasis.
Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.
This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.
Multicentric reticulohistiocytosis in children: two case reports and a literature review.
The report describes two boys with multicentric reticulohistiocytosis (MRH), a disorder uncommon in children and liable to be mistaken for juvenile idiopathic arthritis.
Combination therapy of carbon dioxide laser with topical halometason cream and 308 nm excimer laser for the treatment of vitiligo: an optimized combined treatment protocol.
This randomized controlled trial evaluated fractional CO₂ laser plus topical halometasone cream and 308-nm excimer lamp therapy for refractory non-segmental vitiligo, compared with excimer therapy, a topical calcineurin…
Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.
This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.
Balancing safety and efficacy in photodynamic therapy for facial port-wine stains in children aged 2-7 years: a prospective controlled study of light-intensity optimization.
This open-label, prospective controlled study compared two light intensities for hemoporfin-mediated photodynamic therapy in children aged 2–7 years with facial port-wine stains.
Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.
This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.
5-Aminolevulinic acid-based photodynamic therapy used as a long-term management approach for refractory lichen sclerosus.
A 37-year-old man with more than 10 years of genital lichen sclerosus had recurrence after surgical resection, which left permanent anatomical deformity.
Blood, ink, and flies: A case report on the house fly (Musca domestica) feeding on active tattooing wounds.
During a tattoo session, a healthy 32-year-old man in Germany experienced repeated landing and feeding attempts by house flies on freshly wounded skin of his right lower leg.
Inherited epidermal differentiation disorders (EDD) in pediatric patients from a single Italian referral Center.
A retrospective review at an Italian referral center described three children with congenital, clinically heterogeneous inherited epidermal differentiation disorders.
Extraosseous 99m Tc Methylene Diphosphonate Uptake in Perianal Dystrophic Calcification : Incremental Value of Single-photon Emission CT/CT.
A 57-year-old woman underwent three-phase 99mTc methylene diphosphonate bone scintigraphy for persistent right hip pain following femoral neck fracture fixation.
Long-term efficacy of lebrikizumab in treating head, neck and face involvement in patients with moderate-to-severe atopic dermatitis.
This post hoc analysis of phase III trials assessed head, neck, and face (HNF) outcomes with lebrikizumab in adolescents and adults with moderate-to-severe atopic dermatitis.
Metal Hypersensitivity Reactions Following Spinal Implants: A Systematic Review.
This systematic review examined clinical presentation, diagnostic approaches, and outcomes of metal hypersensitivity after spinal implant surgery in adults.
Isolated Bilateral Periocular Lupus Miliaris Disseminatus Faciei: A Clinicopathological Mimicker of Granulomatosis With Polyangiitis.
A healthy young adult man presented with symmetrical papules confined to both periocular regions. Eyelid biopsy showed suppurative necrotizing granulomatous inflammation, prompting concern for granulomatosis with…
Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.
ADDRESS was a global, phase III, multicentre, randomised, double-blind, placebo-controlled trial of adults with newly diagnosed or relapsing moderate-to-severe pemphigus.
Oral mucous membrane pemphigoid as a window to systemic autoimmunity: two cases associated with rheumatoid arthritis and Sjögren's disease.
Two women presented with oral mucous membrane pemphigoid (MMP) in the setting of systemic autoimmunity. A 68-year-old woman with longstanding rheumatoid arthritis had recurrent oral ulcerations confirmed as MMP on…
Approach to the patient with APS-1/APECED.
This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.
Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.
A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone.
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