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557 articles
May 202624
Phase Ib/II Study of Preliminary Efficacy, Safety and Pharmacodynamics of MG-K10, a Humanised Monoclonal Antibody Targeting IL-4Rα, in Adult Chinese Patients With Asthma.
This Phase Ib/II randomized controlled trial evaluated the efficacy, safety, and pharmacodynamics of MG-K10, a monoclonal antibody targeting IL-4Rα, in Chinese adults with moderate-to-severe asthma.
Hair analysis of formoterol as a novel tool to assess long-term inhalation medication adherence: Data from the TRICOLON trial.
This randomized controlled trial investigated the use of hair analysis to measure long-term adherence to inhaled formoterol in patients with COPD.
Obstructive sleep apnea and idiopathic intracranial hypertension: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the prevalence of obstructive sleep apnea (OSA) in adults with idiopathic intracranial hypertension (IIH) using polysomnography and the Berlin Questionnaire.
Diagnostic accuracy of metagenomic next-generation sequencing for invasive pulmonary aspergillosis: A systematic review and meta-analysis.
This meta-analysis evaluated the diagnostic accuracy of metagenomic next-generation sequencing (mNGS) for invasive pulmonary aspergillosis (IPA) across twelve studies.
Efficacy and potential mechanisms of alkaloids in animal models for pulmonary fibrosis: a study integrating preclinical systematic review and meta-analysis, network pharmacology and molecular docking.
This meta-analysis and systematic review evaluated the efficacy of alkaloids in treating pulmonary fibrosis (PF) using data from 35 randomized controlled trials involving 548 animals.
Proportional Assist Ventilation and Respiratory Effort Monitoring During Transition to Spontaneous Breathing.
This physiological randomized crossover study assessed whether the PAV+ work-of-breathing bar accurately reflects respiratory effort in 35 subjects being weaned from mechanical ventilation.
Clinical efficacy of chronotherapy-based auricular acupoint therapy combined with CPAP in comorbid obstructive sleep apnea and insomnia.
This randomized controlled trial evaluated the efficacy of chronotherapy-based auricular acupoint therapy combined with CPAP in 114 patients with comorbid obstructive sleep apnea and insomnia (COMISA).
Extended Continuous Positive Airway Pressure in Infants Born Preterm Decreases Intermittent Hypoxemia: A Secondary Analysis of a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial evaluated the effects of extended continuous positive airway pressure (eCPAP) versus discontinued CPAP (dCPAP) on intermittent hypoxemia (IH) in stable preterm…
Comparison of PD-L1 expression between biopsy specimens and surgical resection specimens in non-small cell lung cancer: a meta-analysis.
This meta-analysis compared PD-L1 positivity in biopsy and surgical resection specimens from patients with non-small cell lung cancer, drawing on 13 studies involving 966 patients.
Fan Therapy for Alleviating Dyspnea in Adults: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of fan therapy for alleviating dyspnea in adults, analyzing 15 studies with 623 participants.
Are Wearable Sleep-Tracking Devices Reliable Alternatives to Polysomnography? A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed wearable sleep trackers against simultaneous laboratory polysomnography (PSG) in healthy adults.
Long-Term Outcomes After Proton Therapy Versus Intensity Modulated Photon Radiation Therapy With Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: Post Hoc Analysis of a Prospective Randomized Trial.
This post hoc analysis of a prospective randomized trial compared long-term outcomes after passive scattering proton therapy (PSPT) versus intensity modulated photon radiation therapy (IMRT), each given with concurrent…
Glucagon-Like Peptide-1 Receptor Agonists in Asthma and Obesity-Associated Asthma: A Systematic Review of Clinical Outcomes and Translational Mechanisms.
This systematic review evaluated the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on asthma outcomes, particularly in individuals with obesity and type 2 diabetes.
Phase-resolved functional lung MRI detects single-dose and sustained bronchodilator responses in COPD in a randomized crossover trial.
This randomized controlled trial evaluated the effects of tiotropium/olodaterol on phase-resolved functional lung MRI parameters in 32 patients with moderate-to-severe COPD.
Efficacy of BiPAP/CPAP versus COT in patients with obstructive sleep apnea or obesity undergoing sedated gastroenteroscopy: a meta-analysis.
This meta-analysis evaluated the efficacy of bilevel or continuous positive airway pressure (BiPAP/CPAP) versus conventional oxygen therapy (COT) in preventing hypoxemia during sedated gastroenteroscopy in patients with…
A Rare Case of Four-year Complete Metabolic Response in Multisystem Anti-Jo-1 Antisynthetase Syndrome Assessed by 18 F-FDG PET/CT.
A patient with anti-Jo-1 positive antisynthetase syndrome presented with muscular, articular, cutaneous, and pulmonary involvement.
From chronic abscess to acute respiratory distress syndrome (ARDS): A case of recurrent melioidosis in Sri Lanka.
A 31-year-old previously healthy man presented with a recurrent chest wall abscess and developed fulminant pneumonia, leading to acute respiratory distress syndrome (ARDS) eight months after incomplete treatment for…
Steroid Therapy in Community-Acquired Pneumonia: An Updated Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of corticosteroid therapy on mortality and morbidity in 5,866 adults with community-acquired pneumonia (CAP).
Chair-based versus standard home exercise programs in people with COPD: A randomized controlled trial.
This randomized controlled trial compared chair-based and standard home exercise programs in 64 patients with stable COPD. Both interventions improved symptoms and quality of life, but the chair-based group showed…
Tract Embolization versus No Embolization after CT-Guided Lung Biopsy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of tract embolization (TE) in preventing pneumothorax and chest tube placement after CT-guided lung biopsy.
Rapid Relief of Breathlessness With Fast-Acting Opioids and Benzodiazepines: A Systematic Review.
This systematic review evaluated the effectiveness and safety of fast-acting opioids and benzodiazepines for rapid relief of breathlessness in adults with advanced or severe acute disease.
Why breath-by-breath tidal volume is useful for HMV monitoring?
The case report discusses the utility of breath-by-breath tidal volume (VT) monitoring in home mechanical ventilation (HMV) for pediatric patients.
Organizing Pleuritis Presenting as Recurrent Lymphocyte Predominant, Exudative Effusion.
An older man with extensive asbestos exposure presented with recurrent unilateral lymphocytic exudative pleural effusion. Despite multiple thoracenteses, his condition did not improve.
A Meta-Analysis-Based Risk Score for Predicting Radiation Pneumonitis After Thoracic Radiation Therapy for Lung Cancer.
This meta-analysis developed and validated a risk score for predicting radiation pneumonitis (RP) in lung cancer patients undergoing thoracic radiation therapy.
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