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495 articles

April 20268

Clinical ResearchOphthalmology

Efficacy of repeated red-light laser therapy for myopia control in Australian children: a pilot randomised controlled trial.

This pilot randomised controlled trial assessed repeated red-light laser (RLRL) therapy for myopia control in 34 multi-ethnic Australian children aged 8–13 years.

Clin Exp OptomApr 8, 2026Read summary
Case ReportNeurology

Isolated fourth cranial nerve palsy in a patient treated with pembrolizumab: a case report.

A 76-year-old man developed sudden vertical binocular diplopia six weeks after starting adjuvant pembrolizumab following resection of cutaneous melanoma. Examination showed an isolated right superior oblique palsy.

StrabismusApr 8, 2026Read case
Case ReportAllergy & Immunology

Anaphylactic Shock During Oculofacial Plastic Surgery in a Patient With Midazolam and Tetracaine Allergies.

A 56-year-old woman developed facial flushing, hypotension, and oxygen desaturation during elective oculofacial plastic surgery after exposure to tetracaine eye drops, intravenous midazolam and propofol, and a local…

Ophthalmic Plast Reconstr SurgApr 8, 2026Read case
Case ReportOphthalmology

Congenital Upper Eyelid Entropion in an Extremely Low Birth Weight Neonate: Early Surgical Correction to Prevent Corneal Injury.

A late preterm neonate weighing 900 g presented with bilateral congenital upper eyelid entropion and a right corneal ulcer.

Ophthalmic Plast Reconstr SurgApr 8, 2026Read case
Clinical ResearchOphthalmology

Three hundred sixty-degree prophylactic laser retinopexy versus focal laser during rhegmatogenous retinal detachment repair: A systematic review and meta-analysis.

This systematic review and meta-analysis compared intraoperative 360-degree prophylactic laser with focal laser during pars plana vitrectomy for rhegmatogenous retinal detachment.

Acta OphthalmolApr 6, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Vitrectomy After Cataract Surgery as a Patient Safety Indicator: A Rapid Review to Support Benchmarking Within the Austrian Inpatient Quality Indicators Framework.

This rapid review and meta-analysis assessed whether vitrectomy rates can validate the Austrian Inpatient Quality Indicator (A-IQI) for complications during or after cataract surgery.

J Patient SafApr 2, 2026Read summary
Clinical ResearchRheumatology

Risk of Retinopathy Associated with Long-Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined hydroxychloroquine retinopathy (HCQ-R) prevalence, cumulative incidence, and risk factors in adults with rheumatic diseases receiving long-term…

Arthritis Care Res (Hoboken)Apr 2, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Preservative-free 0.01% bimatoprost versus other formulations for glaucoma and OHT: Systematic review and meta-analysis of efficacy and safety.

This systematic review and Bayesian network meta-analysis assessed efficacy and safety of preservative-free bimatoprost 0.01% versus preserved or higher-concentration bimatoprost in adults with glaucoma or ocular…

Eur J OphthalmolApr 1, 2026Read summary

March 202616

Case ReportOphthalmology

Ophthalmological phenotype associated with biallelic CPAMD8 variants: first report in Mexican patients.

Two unrelated Mexican patients with anterior segment dysgenesis had bilateral iris hypoplasia, ectropion uveae, zonular anomalies, and secondary childhood glaucoma.

Ophthalmic GenetMar 31, 2026Read case
Case ReportMedical Genetics

Isolated bull's eye maculopathy in two siblings with biallelic TULP1 variants.

Two siblings were evaluated for bull’s eye maculopathy. Multimodal retinal imaging showed the macular finding, while full-field electroretinography and structural assessment found no functional or anatomic evidence of…

Ophthalmic GenetMar 30, 2026Read case
Case ReportMedical Genetics

Primary congenital glaucoma in a patient with Coffin-siris syndrome type 1 due to an ARID1B mutation: a novel association.

A six-month-old girl with Coffin-Siris syndrome type 1 presented with tearing from both eyes and light sensitivity. Examination showed megalocornea, right inferior corneal edema, elevated intraocular pressure, increased…

Ophthalmic GenetMar 30, 2026Read case
Case ReportOphthalmology

Regression of Recalcitrant Corneal Neovascularization and Graft Revival With Systemic Bevacizumab: A Case Report.

A 64-year-old woman developed bullous keratopathy and deep stromal corneal neovascularization after phakic intraocular lens implantation.

CorneaMar 30, 2026Read case
Case ReportMedical Genetics

A novel case of Heimler syndrome in a young child with compound heterozygous PEX26 mutations: clinical and genetic insights with literature review.

A male infant born at 36 weeks had congenital bilateral sensorineural hearing loss, confirmed by abnormal auditory brainstem responses, and received bilateral cochlear implants.

Ophthalmic GenetMar 29, 2026Read case
Clinical ResearchOphthalmology

Anti-vascular endothelial growth factor and choroidal thickness in retinal vein occlusion: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed changes in subfoveal choroidal thickness (SFCT) and best-corrected visual acuity after intravitreal anti-VEGF therapy in adults with retinal vein occlusion.

Surv OphthalmolMar 28, 2026Read summary
Case ReportMedical Genetics

Characterization of ARB in twins: in-trans frameshift and deep intronic BEST1 variants.

Ten-year-old dizygotic twins presented with bilateral reduced visual acuity and characteristic retinal findings, including multifocal yellow-white flecks, subretinal hyperreflective material with interlaminar splitting…

Ophthalmic GenetMar 26, 2026Read case
Clinical ResearchOphthalmology

Efficacy and adherence to glaucoma treatment depending on eye drop application technique: A crossover randomized clinical trial.

This randomized crossover trial compared patient education with a medical device for improving eye-drop use among 45 patients with primary open-angle glaucoma over 120 days.

Eur J OphthalmolMar 25, 2026Read summary
Case ReportOphthalmology

An unusual case of Kabuki Syndrome with retinal ischaemia and neovascular glaucoma.

A 44-year-old woman with genetically confirmed Kabuki syndrome presented with bilateral intraocular pressures of approximately 50 mmHg, longstanding poor vision and high myopia.

Eur J OphthalmolMar 23, 2026Read case
Clinical ResearchOphthalmology

The efficacy and safety of reducing intraocular pressure to single-digit levels in Normal-tension glaucoma: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether lowering intraocular pressure (IOP) to single-digit levels benefits treated patients with progressive normal-tension glaucoma.

Acta OphthalmolMar 20, 2026Read summary
Case ReportOphthalmology

Epithelial Downgrowth Mimicking Recurrent Retroprosthetic Membrane After Boston Keratoprosthesis Implantation.

A 74-year-old monocular man with prior penetrating corneal injury, multiple failed corneal transplants, and a Boston type 1 keratoprosthesis developed reduced vision and opaque material behind the device’s optical…

CorneaMar 18, 2026Read case
Clinical ResearchOphthalmology

Systematic Literature Review on the Effect of Cenegermin on Corneal Sensation and Innervation in Patients with Neurotrophic Keratopathy.

This systematic literature review assessed changes in corneal sensation (CS) and corneal innervation (CI) after cenegermin treatment in patients with neurotrophic keratopathy (NK).

J Ocul Pharmacol TherMar 18, 2026Read summary
Clinical ResearchOphthalmology

Beyond keratoplasty: The role of Descemet stripping only in the management of Fuchs endothelial dystrophy-a systematic review and meta-analysis.

This systematic review and meta-analysis assessed Descemet stripping only (DSO) for Fuchs endothelial corneal dystrophy (FECD), including prospective and retrospective clinical series with at least 5 patients and 6…

Surv OphthalmolMar 17, 2026Read summary
Case ReportOphthalmology

Drusenoid macular dystrophies in Singaporean Chinese: first report of Doyne honeycomb retinal dystrophy and late-onset retinal degeneration from Southeast Asia.

We report two ethnic Chinese families affected by distinct drusenoid inherited maculopathies: Doyne Honeycomb Retinal Dystrophy (DHRD) and Late-Onset Retinal Degeneration (L-ORD)-to expand their recognized phenotypic…

Ophthalmic GenetMar 15, 2026Read case
Clinical ResearchOphthalmology

Photodynamic therapy and anti-vascular endothelial growth factor for acute central serous chorioretinopathy: An updated systematic review and meta-analysis.

This PRISMA-compliant systematic review and meta-analysis compared photodynamic therapy (PDT) and anti-vascular endothelial growth factor (anti-VEGF) treatment with observation for acute central serous chorioretinopathy…

Surv OphthalmolMar 14, 2026Read summary
Clinical ResearchOphthalmology

Lidocaine gel provides superior analgesia compared to oxybuprocaine drops in pterygium surgery: A double-masked randomized trial.

This double-masked randomized trial compared topical 2% lidocaine gel with 0.4% oxybuprocaine drops for anesthesia during pterygium surgery in adults with bilateral primary nasal pterygia.

Eur J OphthalmolMar 10, 2026Read summary

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