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485 articles
March 202616
A pediatric case of C3 glomerulonephritis initially misclassified as IgA nephropathy with a favorable response to C3-targeted therapy.
A previously healthy 13-year-old girl presented with nephrotic and nephritic syndrome and low serum C3. Her first biopsy showed mesangioproliferative glomerulonephritis with dominant IgA deposits, leading to an initial…
Exosomes in diabetic kidney disease: pathogenesis, biomarker discovery, and emerging therapeutics-a comprehensive systematic review.
This comprehensive systematic review examines research on exosomes in diabetic kidney disease (DKD), including their roles in disease mechanisms, biomarker discovery, and potential therapeutic applications.
Severe renovascular hypertension in an infant with a SMAD3 gene variant.
A boy described at age 4 had severe renovascular hypertension beginning in infancy, with left ventricular hypertrophy as hypertension-mediated organ damage.
Comparison between effectiveness and safety of plasma therapy and complement inhibitors for the treatment of atypical hemolytic uremic syndrome: a systematic review and meta-analysis of real-world data.
This systematic review and meta-analysis compared plasma therapy (PT) with complement inhibitors (CIs) for atypical hemolytic uremic syndrome using 106 observational cohort studies.
Severe systemic lupus erythematosus with thrombotic microangiopathy: rescue therapy with pegcetacoplan.
A 12-year-old girl with severe lupus nephritis and refractory thrombotic microangiopathy remained dialysis-dependent for several months despite intensive immunosuppression, including terminal complement blockade with…
The impact of postoperative acute kidney injury on survival after surgery for type A aortic dissection repair: Results from over 6000 patients.
This systematic review and meta-analysis examined long-term survival after surgical repair of type A aortic dissection according to postoperative acute kidney injury (AKI) status.
Comparative efficacy of low-concentration trisodium citrate and low-concentration heparin for locking central venous hemodialysis catheters: a randomized controlled study.
This randomized controlled study compared 5% trisodium citrate (TSC) with unfractionated heparin (UFH) 1,000 U/mL as locking solutions in 204 patients receiving hemodialysis through central venous catheters.
Pulmonary Involvement in ANCA-associated Vasculitis Overlapping with Long-standing Systemic Lupus Erythematosus.
A 74-year-old woman with long-standing systemic lupus erythematosus (SLE) presented with fever and bilateral centrilobular pulmonary nodules with bronchial wall thickening on computed tomography.
Helicobacter pylori Eradication Therapy-induced Severe Hypoglycemia in a Hemodialysis Patient with Type 2 Diabetes Mellitus.
A 48-year-old man with type 2 diabetes receiving hemodialysis developed recurrent severe hypoglycemia while taking repaglinide during Helicobacter pylori eradication therapy with vonoprazan, amoxicillin, and…
Impact of renal dysfunction on immediate versus staged revascularization of non-culprit lesions in patients with ST segment elevation myocardial infarction: a pre-specified subgroup analysis of the randomized MULTISTARS AMI trial.
This pre-specified subgroup analysis of the randomized, multicentre MULTISTARS AMI trial examined whether baseline renal dysfunction affected outcomes with immediate versus staged PCI of non-culprit lesions in patients…
Acute Kidney Injury and Extreme Rhabdomyolysis due to Carnitine Palmitoyltransferase II Deficiency: A Case Report.
A 47-year-old man presented with influenza-like symptoms and rapidly developed extreme rhabdomyolysis, with creatine kinase >126,800 IU/L, dark urine, metabolic acidosis, multiorgan dysfunction, and acute kidney injury…
Severe acute kidney failure due to double-seropositive anti-GBM glomerulonephritis in a child: a case for rituximab therapy.
An 11-year-old girl presented with rapidly progressive glomerulonephritis and kidney failure requiring kidney replacement therapy.
From post-infectious glomerulonephritis to complement-mediated aHUS: a diagnostic challenge.
A 4-year-old boy presented with edema, hypertension, hematuria, and reduced urine output. Testing showed low C3 and impaired kidney function, and biopsy confirmed post-infectious glomerulonephritis (PIGN).
Tubulointerstitial Nephritis with IgM-positive Plasma Cells Requiring Temporary Hemodialysis.
A 63-year-old Japanese woman was diagnosed with severe kidney dysfunction that required hemodialysis. Testing revealed an elevated serum IgM level (2,650 mg/dL).
IgA Vasculitis Developing during Trastuzumab Emtansine Therapy for HER2-positive Breast Cancer.
An elderly woman receiving trastuzumab emtansine (T-DM1) for HER2-positive breast cancer developed purpura, hematuria, proteinuria, and reduced renal function.
Optimizing diagnosis and management of patients with ENPP1 deficiency: an expert opinion.
This expert-opinion article discusses ENPP1 deficiency, a genetic disorder caused by loss-of-function mutations and associated with low circulating inorganic pyrophosphate, bone hypomineralization, soft-tissue…
February 20268
Single-dose versus multi-dose steroid therapy in pediatric nephrotic syndrome: a systematic review and meta-analysis.
This systematic review and meta-analysis compared once-daily with divided-dose prednisolone in children with steroid-sensitive nephrotic syndrome.
Safe use of ribociclib in a patient with HR+/HER2- metastatic breast cancer receiving chronic hemodialysis.
A 59-year-old woman with end-stage kidney disease receiving hemodialysis three times weekly was diagnosed with hormone receptor-positive, HER2-negative metastatic breast cancer involving bone.
Association of pruritus with comorbidities and survival in chronic kidney disease: a narrative review of the pre-difelikefalin era literature.
This systematic literature review examined associations between chronic kidney disease–associated pruritus (CKD-aP) and comorbidities or survival in studies published from January 2000 to August 2022, before…
Steroid-induced adrenal insufficiency in children with nephrotic syndrome: a systematic review.
This systematic review evaluated steroid-induced adrenal insufficiency (AI) in children with idiopathic nephrotic syndrome treated with corticosteroids.
Coexistence of acute post-streptococcal glomerulonephritis and acute rheumatic fever: case report and systematic review.
A 15-year-old boy developed ankle pain and eyelid and limb edema after a throat infection. Investigations showed nephritic syndrome and elevated antistreptolysin O levels; echocardiography demonstrated rheumatic…
Low-density lipoprotein apheresis for recurrent focal segmental glomerulosclerosis in pediatric kidney transplant recipients: a systematic review and meta-analysis.
This systematic review and descriptive meta-analysis assessed low-density lipoprotein apheresis (LDL-A) for recurrent focal segmental glomerulosclerosis in pediatric kidney transplant recipients.
Invasive Pneumococcal Disease Presenting with Pyogenic Spondylitis in a Patient on Chronic Hemodialysis Who Previously Received a Pneumococcal Vaccine.
A woman receiving chronic hemodialysis presented with fever during a routine session, without focal signs. Blood cultures grew Streptococcus pneumoniae serotype 38, a non-vaccine serotype, despite prior pneumococcal…
Efficacy and safety of budesonide for the treatment of IgA nephropathy: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of budesonide formulations in people with biopsy-proven IgA nephropathy.
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