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1303 articles

September 202624

Clinical ResearchGeriatrics

Culturally adapted post-diagnostic dementia support for South Asian people living with dementia and caregivers: a rapid review.

This rapid review examined culturally adapted post-diagnostic dementia support for South Asian individuals and their caregivers.

Age AgeingSep 4, 2026Read summary
Clinical ResearchPsychiatry

Long-term safety and tolerability of lumateperone 42 mg in patients with stable symptoms of schizophrenia: Results from a 1-year open-label study.

This 1-year, open-label, Phase 3 study assessed the safety and efficacy of lumateperone 42 mg once daily in adults with stable schizophrenia. Of 602 treated patients, 229 (38.0%) completed treatment.

Schizophr ResSep 4, 2026Read summary
Clinical ResearchPsychiatry

Adjunctive n-3 PUFA supplementation improves niacin skin flush response and shows biomarker-stratified signals in schizophrenia.

This randomized controlled trial examined adjunctive n-3 PUFA supplementation in patients with schizophrenia (SZ), assessing niacin skin flush response (NSFR) and symptoms over 21 days.

Schizophr ResSep 4, 2026Read summary
Clinical ResearchPsychiatry

Psilocybin-induced changes in electroencephalography link acute and long-term effects.

This double-blind, placebo-controlled crossover trial examined electroencephalographic changes after psilocybin in 20 healthy participants.

J PsychopharmacolSep 4, 2026Read summary
Clinical ResearchPsychiatryOpen access

Substance use and co-occurring mental health conditions among adolescents and young adults in North America: a systematic review.

This systematic review examined the prevalence and associated factors of substance use and co-occurring mental health conditions among adolescents and young adults in North America.

BMC PsychiatrySep 3, 2026Read summary
Clinical ResearchPsychiatry

Applications and outcomes of virtual reality in inpatient psychiatry: A systematic review.

This systematic review evaluated the applications and outcomes of virtual reality (VR) in inpatient psychiatry, analyzing 37 studies involving 1,004 patients.

Psychol MedSep 3, 2026Read summary
Clinical ResearchPsychiatryOpen access

Implementing the Primary Care Behavioral Health model into routine practice in Swedish primary care: a pilot trial.

This pragmatic multicenter stepped-wedge clinical trial evaluated the implementation of the Primary Care Behavioral Health (PCBH) model in Swedish primary care, involving 6413 patients.

BMC Health Serv ResSep 3, 2026Read summary
Clinical ResearchPsychiatry

Visual dysfunction and psychosis: A systematic review and meta-analysis.

This systematic review and meta-analysis examined links between visual dysfunction and psychosis-related outcomes across 56 studies, including longitudinal, genetically informed, case-control, cross-sectional, and…

Schizophr ResSep 3, 2026Read summary
Clinical ResearchPsychiatry

Addressing fusiform gyrus dysfunction in schizophrenia, theory of mind, and implications for antipsychotics' response and resistance: A systematic review and critical appraisal.

This systematic review examined fMRI studies of fusiform gyrus (FG) activation and functional connectivity in people with schizophrenia compared with healthy controls.

Neurosci Biobehav RevSep 3, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Digital Mindfulness Intervention for Pregnant Women With Affective Disorders and Acute Stress Reactions: Prespecified Secondary Analysis of a Randomized Controlled Trial.

This study evaluated the effectiveness of an 8-week digital mindfulness-based intervention (eMBI) compared to treatment as usual (TAU) in 147 pregnant women with ICD-10 affective or stress-related disorders.

J Med Internet ResSep 2, 2026Read summary
Clinical ResearchPsychiatry

Evaluation of Sexual Function With Adjunctive Lumateperone in Patients With Major Depressive Disorder.

This randomized controlled trial evaluated the effects of adjunctive lumateperone 42 mg/day on sexual function in adults with major depressive disorder (MDD) who had inadequate response to antidepressant therapies.

J Clin PsychiatrySep 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Acute exercise for anxiety reduction in children and adolescents: a meta-analysis of developmental, contextual, and modality-specific effects.

This meta-analysis evaluated the immediate effects of acute exercise on state anxiety in children and adolescents aged 6-18 years.

Eur J PediatrSep 2, 2026Read summary
Clinical ResearchPsychiatry

Sugar-sweetened beverages consumption and the risk of depression in youth: A systematic review and meta-analysis of observational studies.

This systematic review and meta-analysis pooled observational evidence on sugar-sweetened beverage (SSB) consumption and depression in youth.

J Psychiatr ResSep 2, 2026Read summary
Case ReportNeurology

Pearls & Oy-sters: DPPX Antibody-Associated Encephalitis in a Patient With Diarrhea, Tremor, Ocular Flutter, and Cognitive-Psychiatric Changes.

A 57-year-old man presented with a 2-month history of progressive gastrointestinal symptoms, followed by neurological manifestations including tremor, myoclonus, and cognitive changes.

NeurologySep 1, 2026Read case
Clinical ResearchPsychiatryOpen access

Cognitive Behavioral Therapy vs Media Literacy for Prevention of Gaming Disorder and Unspecified Internet Use Disorder: A Randomized Clinical Trial.

This randomized clinical trial evaluated the effectiveness of cognitive behavioral therapy (CBT) versus a media literacy intervention for preventing gaming disorder and unspecified internet use disorder among…

JAMA Netw OpenSep 1, 2026Read summary
Case ReportPsychiatry

Hydrocortisone for Secondary Prevention of Post-Traumatic Stress Disorder: A Case Report.

An Active-Duty Marine experienced a traumatic event during an emergency medical technician shift, leading to a diagnosis of Acute Stress Reaction.

Mil MedSep 1, 2026Read case
Clinical ResearchPsychiatryOpen access

Effectiveness of Mobile-Delivered Exercise and Yoga Programs on Depressive Symptom Reduction in Employees: Randomized Controlled Trial.

This randomized controlled trial evaluated the effectiveness of mobile-delivered exercise and yoga programs on reducing depressive symptoms among full-time employees.

JMIR Hum FactorsSep 1, 2026Read summary
Case ReportPsychiatryOpen access

Hope as a Therapeutic Imperative for Treatment Resistant Depression.

Treatment-resistant depression poses substantial clinical challenges, particularly following multiple unsuccessful pharmacologic treatments.

Bipolar DisordSep 1, 2026Read case
Case ReportPsychiatryOpen access

Serial Fetal Heart Rate Monitoring During Electroconvulsive Therapy in Late Pregnancy: A Case Report of Transition From Succinylcholine to Rocuronium Reversed With Neostigmine.

A 30-year-old primigravida at 30 weeks of gestation presented with severe major depressive disorder and suicidal ideation. Electroconvulsive therapy (ECT) was initiated at 32 weeks, initially using succinylcholine…

Neuropsychopharmacol RepSep 1, 2026Read case
Clinical ResearchPsychiatryOpen access

Managing Sleep in Bipolar Disorder: An Overview of Pharmacological and Non-Pharmacological Interventions.

This systematic review evaluated the efficacy and safety of pharmacological and non-pharmacological interventions for sleep disturbances in individuals with bipolar disorder (BD).

Bipolar DisordSep 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Care Navigation for Methamphetamine Use Disorder: A Randomized Clinical Trial.

This randomized clinical trial evaluated the effectiveness of dedicated care navigation for patients with methamphetamine use disorder in a safety-net health system in Denver, Colorado.

JAMA Netw OpenSep 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Internet-Delivered Cognitive Behavioral Therapy for Fathers With Postnatal Depression: Randomized Controlled Trial of DadBooster.

This randomized controlled trial evaluated the efficacy of DadBooster, an online cognitive behavioral therapy program, for treating postnatal depression in fathers.

J Med Internet ResSep 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

An Open-Label Study Investigating the 5-HT 2A Receptor Occupancy of Remlifanserin (ACP-204) With the PET Radioligand [ 18 F]Altanserin in Healthy Male Participants.

This Phase 1 open-label study evaluated the 5-HT 2A receptor occupancy of remlifanserin (ACP-204) in 16 healthy male participants using PET imaging with [18F]altanserin.

Clin Pharmacol Drug DevSep 1, 2026Read summary
Clinical ResearchPsychiatry

Weighted Blankets to Reduce Anxiety in Hospitalized Patients.

This randomized controlled trial evaluated the impact of a 15-pound weighted blanket on self-reported anxiety in 54 hospitalized adult patients.

Am J Crit CareSep 1, 2026Read summary

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