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845 articles
September 202624
Radiologically occult nasopharyngeal carcinoma: the importance of clinical suspicion and repeat biopsy.
A man in his 40s, previously diagnosed with a left-sided nasopharyngeal lesion, returned with aural fullness and tinnitus. Flexible nasendoscopy revealed subtle changes at the left eustachian tube orifice, but MRI…
Congenital infantile fibrosarcoma of the foot.
A newborn boy presented with a smooth mass measuring approximately 4 cm on the sole of his right foot, initially suspected to be an atypical haemangioma.
Cryptococcal meningitis with cerebrospinal fluid human immunodeficiency virus escape presenting as transient diplopia and areflexia.
A man in his early 40s with stable HIV on antiretroviral therapy presented with transient binocular diplopia and areflexia.
Clinical Perspective on Exophiala dermatitidis, A Systematic Review of Cases Reported Globally over 36 Years.
This systematic review analyzed 77 reported cases of Exophiala dermatitidis infections from 1989 to 2024, highlighting a rise in cases, particularly since 2010.
Postoperative ctDNA-Guided Adjuvant Therapy in Resected Colorectal Cancer: A Systematic Review and Meta-analysis of Prognostic Validity Versus Treatment-Decision Utility.
This systematic review and meta-analysis evaluated the prognostic validity and treatment-decision utility of postoperative circulating tumor DNA (ctDNA) in resected colorectal cancer.
The Dermoscopic Step-Like Border in Circumscribed Hypokeratosis: A Case Involving the Finger and Literature Reappraisal Across Palmar, Plantar, and Digital Lesions.
A patient presented with a circumscribed hypokeratotic lesion on the dorsal finger. Dermoscopy showed a distinct step-like peripheral border.
Zoonotic Sarcocystis hominis and Sarcocystis heydorni in a Bovine Carcass: First Report in Portugal.
Routine inspection of a 55-month-old bovine carcass identified eosinophilic myositis-like lesions in the masseter muscles, prompting partial condemnation of the head.
Talimogene Laherparepvec Response in Recurrent Melanoma During Corticosteroid Replacement for Immune Checkpoint Inhibitor-Induced Adrenal Insufficiency: A Case Report.
A 78-year-old man with recurrent in-transit melanoma of the scalp developed secondary adrenal insufficiency after pembrolizumab therapy, necessitating chronic hydrocortisone replacement.
Maxillary brown tumour as the initial presentation of primary hyperparathyroidism.
A middle-aged woman presented with right cheek swelling due to an expansile maxillary lesion, initially misdiagnosed as a giant cell tumour.
Pheochromocytoma Masquerading as Acute Coronary Syndrome Complicated by Cardiogenic Shock: A CARE-Compliant Case Report.
A 59-year-old man with a history of intermittent chest tightness presented with acute cardiogenic shock, elevated troponin levels, and reduced left ventricular ejection fraction.
Induction FLOT Chemotherapy Prior to Neoadjuvant Chemoradiotherapy in the Treatment of Lower Esophageal and Proximal Gastric Adenocarcinoma: A Phase II, Single-Arm Clinical Trial.
This Phase II, single-arm clinical trial evaluated the effectiveness of induction FLOT chemotherapy followed by neoadjuvant chemoradiotherapy in patients with resectable distal esophageal and proximal gastric…
Resection of a symptomatic complex anterior mediastinal teratoma via sternotomy.
A patient presented with a large anterior mediastinal teratoma measuring 11 × 10 × 10 cm, causing significant compression of the right atrium, right ventricle, superior vena cava, and aorta, along with perforation into…
Tumoral and Systemic Immune Correlates of Response to Concurrent Pembrolizumab and Chemoradiotherapy in Patients with Resected High-Risk Head and Neck Squamous Cell Carcinoma.
This phase I clinical trial evaluated the safety and immune correlates of adjuvant pembrolizumab combined with chemoradiotherapy (CRT) in 34 patients with high-risk, HPV-negative head and neck squamous cell carcinoma.
Clinical and Genomic Insights into the Allodiploid Hybrid Pathogen Aspergillus latus: A Retrospective Case Series.
This case series describes five patients with infections caused by Aspergillus latus, identified through metagenomic next-generation sequencing (mNGS).
Pulmonary Sequestration Masquerading as Bronchiectasis in an Adult: A Case of Diagnostic Dilemma and Literature Review.
A 45-year-old woman presented with fever, cough, and right-sided chest pain, initially diagnosed with bronchiectasis. After treatment, she developed recurrent hemoptysis.
Enteric NK/T Cell Lymphoma-induced Recurrent Perforation in the Intestine: A Case Report.
A 31-year-old female presented with abdominal pain and fever, following a previous jejunal perforation diagnosed as an EBV-associated lymphoproliferative disorder.
Pathological response after neoadjuvant therapy in soft tissue sarcoma: A systematic review of its association with local recurrence, distant metastasis, and survival.
This systematic review assessed whether pathological response after neoadjuvant treatment predicts oncological outcomes in adults with localized soft tissue sarcoma treated with surgery.
PLAG1-rearranged pulmonary metastases from pleomorphic adenoma-spectrum salivary gland neoplasms: A clinicopathologic study of metastasizing pleomorphic adenoma and carcinoma ex pleomorphic adenoma.
Pulmonary metastases from pleomorphic adenoma (PA)-spectrum salivary gland neoplasms are rare and may be difficult to diagnose, particularly in limited pulmonary specimens.
Short Report: First Outbreak of Atlantic Rainforest Spotted Fever in North-Eastern of Brazil-Clinical Features and Eco-Epidemiological Investigation.
Three people developed illness after tick bites while entering Atlantic Forest areas in Ilhéus, Bahia, between March 11 and April 4, 2025.
Biventricular endomyocardial fibrosis with right ventricular hypertrabeculation and rapid progression to heart transplantation: imaging and pathologic correlation.
A 57-year-old male amateur endurance cyclist presented with a two-year history of progressive heart failure, including fatigue, ascites, and lower limb edema.
Histopathologically Confirmed Nasal Rhinosporidiosis in an Adolescent Male Presenting with Long-Standing Right-Sided Nasal Obstruction and Epistaxis: A Case Report.
A 17-year-old male presented with a five-year history of right-sided nasal obstruction and recurrent epistaxis, with a nasal mass that eventually protruded through the nostril.
Small Intestinal Cavernous Hemangioma Presenting with Recurrent Gastrointestinal Bleeding: A Case Report and Narrative Review.
A 74-year-old female experienced recurrent melena for five months, with initial imaging failing to identify a bleeding source.
Chromosome 17p deletion in aplastic anaemia with paroxysmal nocturnal haemoglobinuria clone: a diagnostic challenge.
A 56-year-old female presented with recurrent aphthous ulcers and pancytopenia, showing severe anemia and thrombocytopenia.
A Homozygous Variant in DMRTB1 Is Associated With Non-Obstructive Azoospermia in Humans.
A patient with non-obstructive azoospermia was found by whole-exome sequencing to carry a homozygous DMRTB1 variant, c.792-797del (p.265-266del).
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