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495 articles

April 202624

Clinical ResearchMedical Genetics

Omics in hereditary optic neuropathies: A systematic review of clinical studies with an integrated point of view.

This systematic review examined the application of omics strategies in understanding hereditary optic neuropathies, focusing on 22 clinical studies.

Surv OphthalmolApr 29, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Repeated low-level red-light therapy for improving asthenopic symptoms and accommodation in presbyopia.

This randomized controlled trial evaluated the effectiveness of repeated low-level red light (RLRL) therapy in alleviating asthenopia and enhancing accommodation in 64 adults with presbyopia.

Ann MedApr 28, 2026Read summary
Clinical ResearchOphthalmology

Intense Pulsed Light Therapy for Post-LASIK Dry Eye: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of intense pulsed light (IPL) therapy for managing dry eye syndrome after LASIK surgery.

J Ocul Pharmacol TherApr 28, 2026Read summary
Clinical ResearchOphthalmology

Adult-onset Coats disease: A systematic review and meta-analysis of imaging biomarkers and targeted therapies.

This systematic review and meta-analysis synthesized evidence on clinical features, imaging, mechanisms and treatment outcomes in adults (≥18 years) with confirmed Coats disease.

Acta OphthalmolApr 28, 2026Read summary
Clinical ResearchOphthalmology

Optical coherence tomography measurements in retinopathy of prematurity: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated retinal and choroidal structural changes in individuals with a history of retinopathy of prematurity (ROP) compared to healthy controls.

Eur J OphthalmolApr 27, 2026Read summary
Clinical ResearchOphthalmology

Influence of Capsular Tension Ring Implantation on Rotational Stability of Intraocular Lenses: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of capsular tension ring (CTR) implantation on the rotational stability of intraocular lenses (IOLs) in 1251 eyes.

Semin OphthalmolApr 27, 2026Read summary
Case ReportOphthalmology

Cytomegalovirus Induced Infectious Crystalline Keratopathy After Penetrating Keratoplasty.

A 55-year-old male with a history of multiple penetrating keratoplasties presented with decreased vision and needle-like branching corneal lesions.

CorneaApr 23, 2026Read case
Case ReportDermatology

Adnexal necrobiotic xanthogranuloma presenting as a "kissing" eyelid lesion.

A 50-year-old man presented with a rare form of necrobiotic xanthogranuloma, characterized by a 'kissing' lesion on the upper and lower eyelids.

OrbitApr 21, 2026Read case
Case ReportOphthalmology

Successful Cultivation of Oral Mucosal Epithelial Sheet Following Antifungal Therapy in Cases With Limbal Stem Cell Deficiency.

Four patients with limbal stem cell deficiency, two with Stevens-Johnson syndrome and two with ocular cicatricial pemphigoid, initially presented with Candida albicans contamination in oral mucosal biopsies intended for…

CorneaApr 21, 2026Read case
Case ReportOphthalmology

Fusicolla species as a rare cause of fungal endophthalmitis: A case report.

A 32-year-old female presented with redness and pain in her right eye, leading to a diagnosis of fungal endophthalmitis caused by the rare fungus Fusicolla species.

Diagn Microbiol Infect DisApr 21, 2026Read case
Case ReportOphthalmology

Unusual presentation of cone dysfunction consequent upon a homozygous FAM161A variant.

A 20-year-old male presented with subnormal vision, photophobia, nystagmus, and loss of color vision. Fundus imaging revealed bilateral macular pigmentary mottling and mild retinal vascular attenuation.

Ophthalmic GenetApr 20, 2026Read case
Case ReportOphthalmologyOpen access

Autologous astigmatic corneal lenticule rotation with stromal excimer ablation for high hyperopic astigmatism: 2-year follow-up.

A 41-year-old female with high hyperopic astigmatism (+3.75/-5.50 D) in her left eye underwent a novel procedure combining femtosecond laser-assisted lenticule rotation and excimer laser ablation.

Eur J OphthalmolApr 17, 2026Read case
Case ReportOphthalmology

Unusual closure of a large traumatic macular hole after an unorthodox pars plana vitrectomy.

An 11-year-old male presented with a large traumatic macular hole and a best-corrected visual acuity (BCVA) of counting fingers.

Arch Soc Esp Oftalmol (Engl Ed)Apr 17, 2026Read case
Clinical ResearchOphthalmologyOpen access

Management and presentation of pediatric thyroid eye disease: A systematic review and meta-analysis.

BackgroundPediatric Thyroid Eye Disease (TED) is a rare autoimmune condition primarily associated with Graves' disease. Although usually milder than adult TED, it can still cause functional and psychological morbidity.

Eur J OphthalmolApr 16, 2026Read summary
Case ReportMedical Genetics

A novel CEP78 variant and rod-cone dystrophy in non-consanguineous siblings.

Two non-consanguineous Chinese male siblings presented with severe rod-cone dystrophy (RCD) at ages 7 and 42. Clinical examination, multimodal imaging, and electroretinogram confirmed the diagnosis.

Ophthalmic GenetApr 16, 2026Read case
Case ReportOphthalmology

Systemic isotretinoin-associated Salzmann-like nodular degeneration in a young adult.

A 19-year-old male on systemic isotretinoin therapy developed bilateral corneal nodules resembling Salzmann nodular degeneration, presenting with mild itching.

Arch Soc Esp Oftalmol (Engl Ed)Apr 16, 2026Read case
Case ReportOphthalmology

Case report: The diagnostic and surgical value of UBM in phacolytic glaucoma secondary to traumatic lens subluxation.

A patient presented with phacolytic glaucoma associated with traumatic lens subluxation, a combination that can be difficult to distinguish from other lens-induced glaucomas.

Arch Soc Esp Oftalmol (Engl Ed)Apr 15, 2026Read case
Case ReportOphthalmology

Diplopia and papilledema secondary to thrombosis of the longitudinal venous sinus due to Leiden factor V thrombophilia in a young patient.

A five-year-old girl presented with acute irritability, somnolence, headache, and diplopia. Examination showed preserved vision, marked esotropia with a sixth-nerve palsy, and papilledema.

Arch Soc Esp Oftalmol (Engl Ed)Apr 15, 2026Read case
Case ReportOphthalmology

Under pressure: Foveal mountain peak sign and macular hole after ruptured RAM.

A patient presented with submacular hemorrhage from a ruptured retinal arterial macroaneurysm (RAM). The hemorrhagic clot initially obscured the macula, but two weeks later examination showed a 340 μm full-thickness…

Arch Soc Esp Oftalmol (Engl Ed)Apr 15, 2026Read case
Case ReportMedical Genetics

Radial lattice degenerations and foveal hypoplasia: Late diagnosis of Stickler syndrome in a patient without high myopia.

A 39-year-old woman with unclassified bone-muscle dysplasia and no previous ocular history presented with floaters. Examination showed radial lattice degeneration in both eyes, and optical coherence tomography…

Arch Soc Esp Oftalmol (Engl Ed)Apr 15, 2026Read case
Case ReportOphthalmology

Conjunctival AL amyloidosis as the initial manifestation of multiple myeloma.

A 74-year-old man developed raised yellowish-salmon conjunctival plaques during follow-up after cataract surgery. Incisional biopsy showed subepithelial amyloid deposits, Congo red positive, with immunohistochemistry…

Arch Soc Esp Oftalmol (Engl Ed)Apr 15, 2026Read case
Case ReportOphthalmology

The Qidwai quilt pull-over patch-graft (Q-POP) technique: A novel method for repairing glaucoma tube exposure in conjunctival adhesions.

A monocular patient with severe nystagmus, extensive conjunctival fibrosis, and multiple prior ocular surgeries developed progressive conjunctival thinning over a glaucoma drainage implant tube.

Eur J OphthalmolApr 13, 2026Read case
Clinical ResearchOphthalmology

Patient-reported outcomes and visual function after four refractive strategies in cataract surgery: A randomized controlled trial.

This randomized controlled trial compared patient-reported outcomes (PROMs) and visual function after four refractive strategies in 188 patients with bilateral symptomatic cataract: emmetropia, mini-monovision…

Acta OphthalmolApr 13, 2026Read summary
Case ReportMedical Genetics

Novel heterozygous UCHL1 variant causing severe optic atrophy and vision loss.

Two individuals from one family presented with optic atrophy and progressive vision loss. Neither had demonstrable spasticity, ataxia, or peripheral neuropathy.

Ophthalmic GenetApr 9, 2026Read case

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