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1320 articles
September 202624
Large vessel occlusion stroke in venom-induced consumption coagulopathy after viper envenomation.
A woman in her mid-60s presented with left-sided hemiplegia 6 hours post-viper bite. Investigations revealed profound venom-induced consumption coagulopathy and an acute right middle cerebral artery occlusion.
Effect of periprocedural antithrombotic medication on functional outcome and symptomatic intracranial hemorrhage in patients with carotid tandem lesions.
This post-hoc analysis of the MR CLEAN-MED randomized controlled trial evaluated the impact of periprocedural antithrombotic medication on functional outcomes and symptomatic intracranial hemorrhage in 100 patients with…
Accuracy of Deep Learning in Detecting Cerebral Microbleeds: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of deep learning (DL) models for detecting cerebral microbleeds (CMBs) using MRI in five studies.
Therapeutic Efficacy of Mesenchymal Stem Cells at the Level of Biomarkers in Multiple Sclerosis: A Systematic Review.
This systematic review evaluated the therapeutic efficacy of mesenchymal stem cell (MSC) therapy in multiple sclerosis (MS) by analyzing 17 publications, including five randomized controlled trials.
A case report of sporadic Creutzfeldt-Jakob disease presenting with progressive opsoclonus-myoclonus-ataxia-Plus (OMAS-Plus) phenotype.
A 63-year-old man presented with progressive dysarthria and bulbar symptoms, initially suggestive of myasthenia gravis. His condition deteriorated, leading to right-predominant hemiataxia, polymyoclonus, and cognitive…
PCR-Confirmed Convexity Subarachnoid Neurocysticercosis with Negative Serology: A Case Report.
A patient with a six-month history of focal seizures was diagnosed with convexity subarachnoid neurocysticercosis after surgical excision of a cystic lesion.
A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels.
Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy.
Anxiety disorders, PTSD, and risk of first-ever stroke: A meta-analysis of 11 million participants.
This meta-analysis pooled 23 longitudinal cohort studies involving 11,181,338 participants to assess whether anxiety disorders, obsessive-compulsive disorder (OCD), and PTSD were associated with first-ever stroke.
The post-acute effects of COVID-19 are not associated with robust long-term regional or global brain volumetric changes: A Bayesian meta-analytic evidence.
This Bayesian meta-analysis assessed whether MRI studies show reproducible long-term brain-volume differences after COVID-19.
Mixed-amphetamine salts, extended release for cognitive impairment in persons with MS, a randomized controlled trial.
This double-blind, placebo-controlled, multicentre randomised trial assessed extended-release mixed-amphetamine salts (MAS-XR) for cognitive impairment in people with multiple sclerosis who had impaired Symbol Digit…
Role of Ultrasound in the Evaluation of Diabetics-Related Complication: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed ultrasound findings across diabetes-related complications, including renal, neurological, hepatic, vascular, and musculoskeletal outcomes.
Stroke secondary to cancer-associated coagulopathy: a systematic review.
This systematic review examined cancer-associated coagulopathy (CAC) as a cause of ischemic stroke in cancer patients, analyzing 82 studies.
What can we learn on ALS pathophysiology from iPSC-derived motor neurons harbouring TARBDP mutations: a systematic review.
This systematic review examines the phenotypic characteristics of iPSC-derived motor neurons from ALS patients with TARDBP mutations.
Encephalitic rabies following cat bites: two cases in northern Uganda.
Two Ugandan males presented with rapidly progressive encephalitic rabies following cat bites. Both cases exhibited typical clinical features of rabies, leading to a swift decline in neurological function and ultimately…
Oxygen desaturation in patients with functional seizures: pitfalls for the unwary.
A patient with recurrent functional seizures exhibited documented oxygen desaturation, leading to extensive cardiopulmonary investigations and repeat video-electroencephalogram evaluation.
Scalp necrosis and visual loss in giant cell arteritis: the importance of recognising atypical cutaneous clues.
A 70-year-old woman presented with left hemifacial pain and bilateral forehead skin plaques, initially diagnosed as shingles.
Arthrogryposis as a neuromuscular phenotype: lessons from PIEZO2 loss-of-function.
A 43-year-old woman presented with congenital clubfoot, progressive scoliosis, and distal joint contractures. Neurological examination revealed pure sensory findings, global areflexia, severe sensory ataxia, and a…
Hereditary transthyretin amyloidosis with hand weakness and bulbar involvement.
A 76-year-old man presented with progressive motor weakness, bulbar symptoms, and hand muscle atrophy, initially misdiagnosed as motor neurone disease.
Aphasic status epilepticus complicating hyperosmolar hyperglycaemic state.
A 66-year-old man with type 2 diabetes presented with progressive speech decline and impaired coordination after a fall. EEG confirmed non-convulsive status epilepticus, and MRI revealed transient left temporal changes…
Bilateral facial palsy due to Melkersson-Rosenthal syndrome.
A 29-year-old woman presented with bilateral facial nerve palsy of unknown origin despite extensive testing. After further evaluation, she developed upper lip swelling, which led to the diagnosis of Melkersson-Rosenthal…
Extraosseous Ewing sarcoma of the common fibular nerve.
A 64-year-old woman presented with progressive weakness of the left foot, leading to the diagnosis of an intraneural extraosseous Ewing sarcoma of the common fibular nerve.
Coma from severe spontaneous intracranial hypotension due to a CSF-venous fistula.
A patient presented in a coma due to severe spontaneous intracranial hypotension (SIH) caused by a spinal CSF-venous fistula. The condition led to significant brain sagging, compromising brainstem function.
From Neurophysiological Mechanisms to Rehabilitation After Botulinum Toxin Type A in Post-Stroke Spasticity.
This systematic review and meta-analysis examined the neurophysiological mechanisms of botulinum toxin type A (BoNT-A) in treating post-stroke spasticity (PSS) across 39 studies with 760 patients.
Pure Motor Axonal Neuropathy Associated with Sjögren's Syndrome: A Rare Case Report.
A 47-year-old man with a history of sicca symptoms presented with progressive, asymmetric motor weakness in all four limbs, without sensory involvement.
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