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845 articles
September 202624
Biomarker Detection of Lung Cancers Before Clinical Symptoms or the Use of Traditional Imaging Methods in the ITALUNG Trial.
The ITALUNG trial, a randomized controlled trial, assessed the efficacy of Low-Dose Computed Tomography (LDCT) for lung cancer screening in over 3100 high-risk individuals aged 55-69.
Acute myeloid leukemia arising in treated chronic lymphocytic leukemia/small lymphocytic lymphoma: a challenge in analysis of lineage relationship.
A 75-year-old female with a history of chronic lymphocytic leukemia/small lymphocytic lymphoma, previously treated with obinutuzumab and venetoclax, presented with acute myeloid leukemia characterized by…
Tangier Disease.
Two patients with Tangier disease (TD) were evaluated. The first patient was diagnosed through a tonsillectomy specimen showing histopathological features of TD and had a compound heterozygous variant in the ABCA1 gene.
Psychiatric manifestation of neurosarcoidosis: a systematic review with pooled descriptive analysis of case reports and case series.
Neurosarcoidosis is a rare inflammatory disease with a heterogeneous presentation. Psychiatric manifestations may precede neurological involvement, but their prevalence, diagnostic pattern, and treatment outcomes remain…
Transoral robotic reconstruction of a posterior palatal defect using an upper arm flap following polymorphous adenocarcinoma resection: a novel minimally invasive approach.
A 36-year-old female presented with a 1 × 1 cm swelling on the palate, diagnosed as a polymorphous adenocarcinoma after resection.
Malakoplakia mimicking a colonic tumour: imaging findings, non-surgical management and follow up.
A woman in her 60s with diabetes presented with a mass lesion in the descending colon, which was initially suspected to be malignant based on imaging findings.
Bladder Large Cell Neuroendocrine Carcinoma(LCNEC): A Case Report of Exfoliated Cytology and Pathological Characteristics.
A 77-year-old man presented with recurrent gross hematuria, urinary frequency, urgency, and lumbosacral pain. Imaging revealed a large soft-tissue mass on the bladder wall.
Nasal NUT carcinoma with repeated responses during multimodal treatment incorporating radiotherapy: A case report.
A 40-year-old woman with nasal NUT carcinoma presented with severe symptoms including orbital pain, visual impairment, and lower-limb paralysis after initial surgery. Pathologic evaluation confirmed the diagnosis.
Collagenous gastritis in pediatric patients: Two case reports and literature review.
Two pediatric cases of collagenous gastritis (CG) are reported. The first case involved a 7-year-old girl with severe iron-deficiency anemia and pallor, where EGD revealed fragile gastric mucosa and histopathology…
Endoscopic "Two-Step Method" for resection of a large tumor at the major duodenal papilla: A case report (with video).
A 75-year-old female presented with abdominal distension and was found to have a giant laterally spreading tumor at the major duodenal papilla.
Coinfection of Pneumocystis jirovecii and Aspergillus fumigatus in the lung: A case report.
A 66-year-old male with mantle cell lymphoma and a history of corticosteroid therapy presented with worsening pulmonary symptoms.
Primary breast diffuse large B-cell lymphoma mimicking breast carcinoma: A case report and literature review.
A 59-year-old postmenopausal woman presented with a painless right breast mass, initially suspected to be breast carcinoma based on imaging studies.
Durable disease control following multidisciplinary treatment including pembrolizumab in POLE-mutated dedifferentiated endometrial carcinoma with brain metastases: A case report.
A 58-year-old woman with POLE-mutated dedifferentiated endometrial carcinoma presented with headache, dizziness, and weakness due to multiple brain and pulmonary metastases.
Primary laryngeal paraganglioma with multisystem metastases: A case report.
A patient with laryngeal paraganglioma presented with progressive dysphagia, hoarseness, and dyspnea. Imaging revealed a laryngeal mass, confirmed by histopathology.
Meta-analysis of PAX1/JAM3 methylation performance in high-risk HPV-positive women.
This meta-analysis evaluated the diagnostic performance of PAX1/JAM3 dual-gene methylation testing in high-risk HPV-positive women for detecting high-grade cervical intraepithelial neoplasia (CIN) and cervical cancer.
Helcococcus kunzii as a rare etiological agent of spondylodiscitis partially managed with oral antibiotic therapy in a patient with diabetes mellitus: a case report.
A 62-year-old man with type 1 diabetes mellitus presented with severe lumbar pain, leading to a diagnosis of spondylodiscitis confirmed by MRI.
Fatal Cutaneous Mucormycosis Initially Misdiagnosed as Necrotizing Fasciitis in an Uncontrolled Diabetic Patient: A Case Report Highlighting Diagnostic Delay.
A 64-year-old male with undiagnosed diabetes presented with altered consciousness and extensive necrotic lesions, initially diagnosed as bacterial necrotizing fasciitis.
Death due to intentional consumption/ingestion of caffeine powder: A case report of the forensic and toxicological evaluation of caffeine intoxication.
A man in his late twenties presented with nausea, vomiting, and tachycardia after intentionally ingesting a high dose of powdered caffeine.
Non-Meningothelial Mesenchymal Tumor of the Central Nervous System: Case Report and Literature Review.
A 40-year-old man presented with progressive left-sided paresthesia, leading to the discovery of a supratentorial non-meningothelial mesenchymal tumor (NMMT) via neuroimaging, which revealed a parasagittal mass.
Primary NTRK-rearranged spindle cell sarcoma of the colon with ETV6-NTRK3 fusion.
A man in his late 30s presented with abdominal pain, leading to a CT scan that revealed a large transmural tumor in the colon. The multidisciplinary team opted for immediate surgery without preoperative colonoscopy.
Orbital lymphoma presenting as preseptal cellulitis in a child with ataxia-telangiectasia.
A young child with ataxia-telangiectasia presented with left periorbital swelling, initially treated as a periorbital infection.
Highly viscous ascites prompting reconsideration of cardiorenal syndrome in a patient with advanced CKD after TAVI.
An elderly man with advanced chronic kidney disease and cardiovascular issues developed refractory pleural effusion, ascites, and peripheral edema following transcatheter aortic valve implantation.
Successful hemodialysis withdrawal with glucocorticoid treatment after achieving infection control in a case of crescentic IgA-dominant staphylococcus-associated glomerulonephritis.
A 70-year-old woman presented with bacteremia and multiple abscesses due to methicillin-susceptible Staphylococcus aureus, leading to acute kidney injury and the need for hemodialysis.
Déjà vu.
A male in his mid-20s presented with fever, purpuric rash, neuropathy, marked eosinophilia, hepatic dysfunction, and extensive multisystem thrombosis.
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