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1303 articles
September 202624
Effects of Digital Mental Health Screening Alone and With the Online MINDBODYSTRONG CBT-Based Program on Burnout, Depression, Anxiety, Healthy Behaviors, and Suicidal Ideation in at-Risk Nurses at 3- and 6-Months Post-Intervention: An RCT.
This randomized controlled trial evaluated the effects of a digital mental health screening program alone versus combined with the MINDBODYSTRONG CBT-based program on burnout, depression, anxiety, and suicidal ideation…
Association between sleep paralysis and anxiety: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the association between sleep paralysis and anxiety, involving 5568 participants across 11 studies.
Global prevalence and patterns of benzodiazepine use among adolescents and young adults: A systematic review and meta-analysis.
This systematic review and meta-analysis synthesised observational studies of benzodiazepine use among adolescents and young adults aged 16–30 years. Fifteen studies involving 7,235,912 participants were included.
Effectiveness and moderators of PE and CPT in adult PTSD treatment: a systematic review and meta-analysis.
This meta-analysis evaluated the effectiveness of Prolonged Exposure (PE) and Cognitive Processing Therapy (CPT) for treating PTSD, synthesizing data from 175 treatment arms across 163 studies.
Daratumumab Treatment in Severe Anti-NMDAR Encephalitis: Two Case Reports and Literature Review.
Two patients, aged 21 and 19, presented with severe anti-NMDAR encephalitis, exhibiting neuropsychiatric symptoms, seizures, and dysautonomia. Both required ICU care and did not improve after multiple immunotherapies.
Protocol for project FIERCE: A randomized controlled trial to evaluate a positive emotion-focused meditation intervention for physicians with elevated stress.
This randomized controlled trial will assess the feasibility and efficacy of a six-week mindfulness intervention, the Building Emotional Strength Training (BEST) program, for 90 full-time physicians experiencing…
Relational care in community mental health: Evaluating staff experiences in Intensive Community Care Services (ICCS) vs treatment as usual.
This randomized controlled trial evaluated staff experiences in Intensive Community Care Services (ICCS) compared to Treatment as Usual (TAU) in community mental health.
Transcranial Magnetic Stimulation for Patients with Exposure Therapy Resistant Obsessive-Compulsive Disorder (TETRO): Study Protocol for a Multicenter Randomized Controlled Trial.
This multicenter randomized controlled trial investigates the efficacy and cost-effectiveness of low-frequency (1Hz) rTMS targeting the pre-SMA as an adjunct to exposure therapy in adults with OCD who have not responded…
Mechanisms of impact of mental health peer support in high-, middle- and low-income settings: mediation analysis of the UPSIDES randomised controlled trial.
This multicenter randomized controlled trial examined the mechanisms of peer support (PS) in improving recovery outcomes among 565 adults with severe mental health conditions across various income settings.
No evidence for a generalised predictive processing deficit in psychosis: A meta-analysis.
This meta-analysis evaluated the predictive processing theory of psychosis by analyzing 34 results from 27 studies involving 904 individuals with schizophrenia-spectrum psychosis and 1,039 healthy controls.
Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research.
This systematic review examined barriers and facilitators to implementing pharmacogenomic (PGx) testing for antidepressant use in primary care, utilizing the Consolidated Framework for Implementation Research (CFIR).
Where does the "ἀφημί" (speechless) in nfvPPA come from?: a case study on phonological retrieval and the potent effect of moraic assistance.
A 65-year-old Japanese male with non-fluent/agrammatic variant primary progressive aphasia (nfvPPA) presented with severe speechlessness.
Long-term safety and efficacy of vornorexant in Japanese patients with insomnia: A 52-week open-label, randomized trial.
This multicenter, randomized, open-label trial evaluated the long-term safety and efficacy of vornorexant in 371 Japanese patients with insomnia over 52 weeks.
Polysubstance use after remission in first-episode psychosis: Associations with positive symptoms and self-care.
This analysis of the HAMLETT randomized controlled trial examined substance-use patterns and their associations with symptoms, cognition, and functioning 3 to 6 months after remission in people with first-episode…
Clinical applications of wearable devices for individuals with at-risk substance use and substance use disorders: A systematic review.
This systematic review assessed the feasibility and acceptability of wearable devices that passively collect physiological data among adults with substance use disorders or at-risk substance use.
Proof-of-concept trial of PP-01 for mitigating cannabis withdrawal syndrome in participants with cannabis use disorder.
This Phase 1b/2a randomized, double-blind, placebo-controlled crossover trial assessed PP-01, a combination of nabilone and gabapentin, for cannabis withdrawal in 14 adults with moderate to severe cannabis use disorder.
Exploring the experiences, views, and needs of family members of emergency response workers: a systematic review and meta-synthesis.
This systematic review and meta-synthesis examined the experiences and needs of family members of emergency responders, identifying significant emotional and practical burdens they face.
A Smartphone-Based Ecological Momentary Intervention for Workplace Mental Health: Randomized Controlled Trial.
This randomized controlled trial evaluated the effectiveness of Neurum, a smartphone-based intervention, in reducing workplace stress among 201 working adults over four weeks.
Rapid plaque clearance with anti-amyloid therapy for Alzheimer's disease: in consideration of donanemab treatment duration from real-world cases.
Two patients with early-stage Alzheimer's disease were treated with donanemab, achieving complete amyloid clearance as assessed by amyloid PET scans before their 6th and 9th infusions.
Are co-occurring behavioural health risk factors related to reach and efficacy of in-person versus computer-generated brief alcohol interventions? Findings from a randomized controlled trial.
This randomized controlled trial examined the impact of co-occurring behavioral health risk factors (HRFs) on the reach and efficacy of brief alcohol interventions among 961 at-risk alcohol users in a hospital setting.
Effect of dopamine partial agonist antipsychotics on suicide risk in persons with schizophrenia and schizoaffective disorders: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether dopamine partial agonist antipsychotics (DPAs) affect suicide outcomes in people with schizophrenia or schizoaffective disorders.
A Bayesian network meta-analysis of specific exercise modalities for depressive symptoms in mild cognitive impairment.
This Bayesian network meta-analysis compared exercise modalities for depressive symptoms in people with mild cognitive impairment (MCI), drawing on 19 randomized controlled trials of nine modalities.
Differential predictive performance of machine learning models for schizophrenia relapse prediction using behavioral versus physiological passive sensors: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed passive-sensor machine-learning models for predicting relapse among people with schizophrenia-spectrum disorders.
Efficacy and safety of cannabinoid-based interventions for behavioral and cognitive symptoms in dementia: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of cannabinoid-based interventions for behavioral and cognitive symptoms in dementia, analyzing nine randomized controlled trials with 334…
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