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845 articles
September 202624
Fulminant Secondary HLH Following EBV Reactivation in an Adult With Trisomy 21 After Teplizumab Treatment for Stage 2 Type 1 Diabetes.
A 44-year-old man with trisomy 21 and stage 2 type 1 diabetes developed respiratory, hepatic, and renal failure six days after completing a 14-day course of teplizumab.
Rare ophthalmic complication of tuberculosis meningitis: tuberculosis orbital apex syndrome.
A woman in her mid-60s presented with orbital apex syndrome, characterized by dysfunction of multiple cranial nerves. Diagnostic challenges arose due to the rarity of tuberculosis-related OAS in non-endemic regions.
FAN1 mutation and karyomegalic nephropathy in chronic kidney disease.
A middle-aged female with chronic kidney disease presented for renal biopsy, which showed tubular vacuolization, patchy acute injury, and karyomegaly with bizarre nuclei.
Anti-OJ antibody-positive anti-synthetase syndrome associated with hepatocellular carcinoma.
A man in his 70s with hepatocellular carcinoma presented with progressive proximal muscle weakness and dropped head syndrome.
Fragile X-associated tremor/ataxia syndrome with autoimmune hepatitis requiring liver transplantation.
A man in his mid-60s with Fragile X-associated tremor/ataxia syndrome (FXTAS) and 88 CGG repeats in FMR1 developed autoimmune hepatitis, confirmed by biopsy, leading to liver transplantation.
Low-Grade Salivary Myoepithelial Carcinoma of the Upper Lip Harboring a Novel CARMN/miR143HG::PLAG1 Fusion.
A 48-year-old man presented with a 6-month history of a slow-growing, asymptomatic nodule in the left upper lip. An excisional biopsy revealed a low-grade myoepithelial carcinoma characterized by a multilobulated growth…
Uterine Cervical Tuberculosis Mimicking Malignancy: Case Series from Ethiopia.
Three women aged 29, 33, and 40 years in Ethiopia presented with odorless whitish vaginal discharge, pelvic pain, and abnormal uterine bleeding. Abnormal cervical findings led clinicians to suspect cervical cancer.
Asynchronous bilateral pulmonary pathology: left-sided congenital pulmonary airway malformation with contralateral malignant pleuropulmonary blastoma in an adolescent.
An adolescent boy with a history of left-sided congenital pulmonary airway malformation (CPAM) presented with dry cough, right-sided chest pain, and breathlessness.
Immunoglobulin A-dominant crescentic glomerulonephritis in a teenage refugee with active methicillin-resistant Staphylococcus aureus urinary infection: a diagnostic and therapeutic dilemma.
A teenage refugee presented with rapidly progressive renal failure, nephrotic-range proteinuria, and fluid overload necessitating haemodialysis.
Heterotopic prostatic tissue mimicking prostate cancer: the decisive role of multiparametric MRI.
A man in his 70s was referred for urological evaluation because of a progressive increase in serum prostate-specific antigen levels.
Discordant pathologic response to neoadjuvant human epidermal growth factor receptor 2-directed therapy in primary breast tumour and axillary lymph node metastases.
A patient with HER2-positive breast cancer received neoadjuvant chemotherapy and HER2-directed therapy, showing significant histological response in the primary breast tumor.
Complicated allergic fungal rhinosinusitis: diagnostic complexities and management strategies.
A man in his 60s presented with diplopia, headache, and facial numbness, leading to a diagnosis of bilateral abducens nerve palsy and partial right third nerve palsy.
Systemic light chain amyloidosis presenting as jejunal perforation.
A patient with recurrent uterine cancer presented with jejunal perforation, a rare complication of systemic light chain amyloidosis.
Male breast cancer in Arab populations: a systematic review of molecular, genetic, and clinicopathologic characteristics.
This systematic review analyzed 54 studies involving 1,534 male breast cancer (MBC) patients from Arab countries, revealing that invasive ductal carcinoma is the most common subtype (92.6%).
Simultaneous Thyroid Eye Disease and IgG4-Related Orbital Disease in a Patient With Diabetes Mellitus: A Case Report.
A 72-year-old man with a history of thyroid eye disease and diabetes presented with progressive proptosis and orbital swelling.
A balloon-like cardiac myxoma mimicking a blood-filled cyst.
A 54-year-old woman presented with exertional dyspnea, chest tightness, and intermittent dizziness. Initial evaluations were unremarkable.
A case report of sporadic Creutzfeldt-Jakob disease presenting with progressive opsoclonus-myoclonus-ataxia-Plus (OMAS-Plus) phenotype.
A 63-year-old man presented with progressive dysarthria and bulbar symptoms, initially suggestive of myasthenia gravis. His condition deteriorated, leading to right-predominant hemiataxia, polymyoclonus, and cognitive…
Recurrent breast abscess leading to an incidental diagnosis of tuberculous mastitis: a case report.
A 26-year-old Indian woman presented with a recurrent right breast abscess characterized by a tender, fluctuant swelling. Initial management included incision and drainage.
PCR-Confirmed Convexity Subarachnoid Neurocysticercosis with Negative Serology: A Case Report.
A patient with a six-month history of focal seizures was diagnosed with convexity subarachnoid neurocysticercosis after surgical excision of a cystic lesion.
Pathological complete necrosis after pulmonary thermal ablation: a systematic review and meta-analysis of ablate-and-resect studies.
This systematic review and meta-analysis examined pathological complete tumor necrosis after pulmonary thermal ablation, using eight ablate-and-resect studies comprising 95 evaluable lesions.
Association between hair cortisol concentration and cancer-related outcomes in adult patients: A systematic review.
This systematic review assessed whether hair cortisol concentration (HCC), a marker of cumulative cortisol exposure, is associated with cancer outcomes in adults with confirmed cancer.
NSMCE2 / MMS21 structural variant causes chromosome breakage syndrome with primordial dwarfism and severe lung disease.
Two siblings of non-consanguineous Indian-Jewish ancestry had severe postnatal growth restriction, hypotonia, characteristic facial features, hypothyroidism, late-onset insulin-dependent diabetes, borderline immune…
Stroke secondary to cancer-associated coagulopathy: a systematic review.
This systematic review examined cancer-associated coagulopathy (CAC) as a cause of ischemic stroke in cancer patients, analyzing 82 studies.
Scalp necrosis and visual loss in giant cell arteritis: the importance of recognising atypical cutaneous clues.
A 70-year-old woman presented with left hemifacial pain and bilateral forehead skin plaques, initially diagnosed as shingles.
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