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1357 articles
November 202624
Phase 2 Trial of 89 Zr-Deferoxamine-Daratumumab for CD38-targeted Immuno-PET/CT Detection of Multiple Myeloma.
This prospective phase 2 trial compared CD38-targeted 89Zr-DFO-daratumumab immuno-PET/CT with standard-of-care 18F-FDG PET/CT in 60 participants with multiple myeloma.
Added Value of Preoperative Contrast Enhanced Mammography in Staging of Malignant Breast Lesions (PROCEM): A Randomized Controlled Trial.
This prospective, multicenter randomized controlled trial evaluated whether preoperative contrast-enhanced mammography (CEM) adds value to standard imaging for staging early-stage breast cancer in women eligible for…
Six-Month Music Practice Versus Psychomotor Interventions in Mild Cognitive Impairment: Behavioral and Hippocampal Outcomes.
This pilot randomized controlled intervention study compared six months of intensive musical instrument training with psychomotor interventions in people with mild cognitive impairment (MCI), using matched healthy…
The Effect of Implementing Orem's Self-Care Model on Balance and Fatigue in Patients With Diabetic Neuropathy: A Clinical Trial.
This randomized clinical trial evaluated Orem’s self-care model in 70 patients with diabetic neuropathy recruited by convenience sampling at one clinic.
Peptides for Hair Growth and Treatment of Hair Loss and Alopecia: A Systematic Review.
This systematic review assessed clinical trials of peptide-containing therapies for hair loss in humans. Searches of PubMed, Embase, and the Cochrane Library identified 981 studies, of which 14 met the inclusion…
A Moisturizer With Centella asiatica and Mandelic Acid Reduces Bruising and Speeds Recovery in Mature Skin.
This 12-week multicenter, randomized, blinded, in-use study evaluated a moisturizer containing Centella asiatica and mandelic acid in men and women aged 40 to 60 years with fragile, bruise-prone skin.
Short-Term Pain Outcomes of Trigger Point Injection Versus Dry Needling for Acute Myofascial Low Back Pain in the Emergency Department: A Prospective Randomized Comparative Study.
This prospective randomized comparative study evaluated trigger point injection versus dry needling for acute myofascial low back pain in emergency department patients.
Streptozotocin-based chemotherapy in advanced PanNETs: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed objective response and progression-free survival with streptozotocin (STZ)-containing chemotherapy in advanced pancreatic neuroendocrine tumours.
Airway occlusions to measure inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation.
This multicenter randomized study assessed whether airway occlusion maneuvers can estimate inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation (NIV).
Five-year outcomes of the STOP-AD randomised controlled trial: Long-term effects of early emollient therapy in high-risk infants.
This blinded, single-centre, randomised controlled trial follow-up assessed whether brief neonatal emollient use was associated with lasting effects on atopic dermatitis (AD) in term infants at high risk of AD.
Sociodemographic factors, but not rurality, explain limited variance in fibromyalgia severity: a secondary analysis of 2 randomized clinical trials.
This secondary analysis combined baseline data from 685 participants in two randomized clinical trials to examine whether rural residence and sociodemographic characteristics were associated with fibromyalgia severity.
Effect of Bimekizumab Treatment on Health Status, Work Productivity, and Productivity Costs Through 3 Years in Axial Spondyloarthritis and Psoriatic Arthritis.
This analysis assessed health status, work productivity, and productivity-related costs through 3 years among patients with axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA) treated with bimekizumab in phase…
Bruton Tyrosine Kinase Inhibitors for Systemic Lupus Erythematosus: A Systematic Review of Randomized Controlled Trials.
This systematic review assessed randomized clinical trials of Bruton tyrosine kinase (BTK) inhibitors for systemic lupus erythematosus (SLE), including potential effects on cutaneous disease.
Effects of CT-guided Radiofrequency Versus Microwave Ablation on Pulmonary Function in Individuals with Pulmonary Tumors: A Prospective Multicenter Randomized Trial.
This prospective, multicenter randomized trial compared short-term pulmonary function after CT-guided radiofrequency ablation (RFA) or microwave ablation (MWA) in 138 participants with pulmonary tumors.
Dermabond versus suture fixation for spinal cord stimulator trial lead anchoring: a randomized within-patient controlled trial.
This prospective, randomized within-patient controlled trial compared Dermabond with suture for anchoring bilateral thoracic percutaneous spinal cord stimulator trial leads in 48 adults.
A comparison of the efficacy and safety of direct oral anticoagulants with low molecular weight heparin for venous thromboembolism prophylaxis after total hip arthroplasty : a systematic review and meta-analysis.
This systematic review and meta-analysis compared direct oral anticoagulants (DOACs) with low molecular weight heparin (LMWH) for venous thromboembolism prophylaxis after elective total hip arthroplasty.
Eltrombopag during induction chemotherapy in older patients with newly diagnosed acute myeloid leukemia is safe and reduces platelet transfusion requirements: The EPAG-2015 French Innovative Leukemia Organization phase 2 randomized trial.
The multicentre, phase 2 randomized trial EPAG-2015 evaluated eltrombopag started after induction chemotherapy in patients aged 60 years or older with newly diagnosed acute myeloid leukemia.
Prehospital Pediatric Ventilation Quality Following Use of a Feedback Device: A Randomized Study.
This multicenter, single-anonymized randomized crossover simulation study assessed pediatric manual ventilation by EMS clinicians at 5 agencies across 3 US metropolitan sites.
Prevalence and Geographic Distribution of Molar-Incisor Hypomineralisation in Spain: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed molar-incisor hypomineralisation (MIH) prevalence in Spanish children and adolescents aged 6–18 years.
Anterior Chamber Depth Changes: After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome Versus Control Eyes: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis compared anterior chamber depth (ACD) before and after phacoemulsification in eyes with pseudoexfoliation syndrome (PEX) and control eyes.
A multicenter, prospective, phase 2 trial on proton re-irradiation for patients with previously treated head and neck cancer.
This multicenter, prospective phase 2 trial evaluated proton re-irradiation in patients with previously irradiated head and neck cancer.
Biologics and small molecules for perianal Crohn's disease: a systematic review and meta-analyses of randomized placebo-controlled trials.
This systematic review and meta-analysis pooled placebo-controlled randomized trials of advanced therapies for perianal fistulizing Crohn’s disease.
Effects and Moderators of High-Intensity Interval Training (HIIT) on Physiological Adaptations Among Team-Sport Athletes: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined HIIT added to regular sport-specific training in team-sport athletes. Across 46 studies involving 1204 athletes, HIIT was associated with improvements in several aerobic…
RSV Bivalent Prefusion F Protein Vaccine in Pregnancy and Protection Against RSV-Associated Illness in Infants: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed real-world effectiveness of maternal RSV bivalent prefusion F protein vaccination in preventing RSV-associated lower respiratory tract infection (LRTI) hospitalization…
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