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557 articles
July 202624
All eyes on gas exchange: impact of controlled arterial hypertension on cardiopulmonary function and the effects of high-intensity interval training.
This randomized controlled trial examined the impact of controlled arterial hypertension (AH) on cardiopulmonary function in 38 adults with AH compared to 19 controls.
Pesticide exposure and all health outcomes: An umbrella review of meta-analyses of observational studies.
This umbrella review systematically analyzed 53 meta-analyses of observational studies to evaluate the health outcomes associated with pesticide exposure.
Food Effects on the Pharmacokinetics of Single Dose and Steady-State Ralinepag, a Novel Oral Prostacyclin Agonist, in Healthy Volunteers.
This Phase I clinical trial assessed the pharmacokinetics and safety of ralinepag extended-release in healthy volunteers, comparing fed and fasted states.
First-in-human pilot study of a robotic-assisted system for image-guided trans-thoracic lung biopsy: Clinical feasibility and exploratory post-hoc AI trajectory analysis.
This prospective, single-center clinical trial assessed the feasibility of the Automatic Needle Targeting (ANT-C) robotic system for CT-guided trans-thoracic lung biopsy in 30 patients.
Defining Minimal Clinical Disease Activity and Remission in Severe Asthma: A Modified Delphi Consensus.
This systematic literature review and modified Delphi consensus sought to standardize definitions of minimal clinical disease activity and remission in severe asthma.
Effect of transcutaneous auricular vagus nerve stimulation on postoperative pain in patients undergoing thoracoscopic partial lung resection: a randomized, double-blind, controlled clinical trial.
This randomized controlled trial evaluated the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on postoperative pain in 119 patients undergoing thoracoscopic partial lung resection.
Intrapulmonary Mercury Deposition more than a Decade after Ingestion of a Mercury-Containing Traditional Remedy: A Case Report.
A 52-year-old male farmer presented with an incidental thoracic opacity on imaging, which was identified as a solitary hyperdense nodule in the left lower lobe.
Long-term efficacy and safety of dupilumab in patients enrolled from Latin American centers from the open-label extension LIBERTY ASTHMA TRAVERSE study.
This post hoc analysis of the open-label extension TRAVERSE study examined long-term dupilumab outcomes in patients with moderate-to-severe asthma enrolled at Latin American centers after completing a phase 2b or phase…
Tumorous Endobronchial Tuberculosis Mimicking Lung Neoplasm: A Diagnostic Challenge in a Middle-aged Female.
A 45-year-old woman with obstructive airway disease and type 2 diabetes presented with progressive dyspnea, cough, low-grade evening fever, and weight loss.
Endobronchial Spindle Cell Tumor of Neurogenic Origin with Coexisting Bronchial Anthracofibrosis: A Rare Case Report.
A 69-year-old nonsmoking woman with progressive breathlessness had a 45-year history of exposure to biomass smoke. CT showed right middle-lobe atelectasis with microcalcification and extensive mediastinal…
Safety, pharmacokinetics and pharmacodynamics of TQC3721, an innovative, dual PDE3 and PDE4 inhibitor, in healthy subjects and patients with chronic obstructive pulmonary disease: Randomised, double-blind, placebo-controlled phase I and IIa clinical trials.
This study evaluated the safety, pharmacokinetics, and pharmacodynamics of TQC3721, a dual PDE3 and PDE4 inhibitor, in healthy subjects and COPD patients through randomized, double-blind, placebo-controlled phase I and…
Transient pseudo-P pulmonale unmasking cardiopulmonary interactions in cardiogenic shock.
A 70-year-old male presented with cardiogenic shock and elevated D-dimer levels after thrombolysis, initially raising suspicion for massive pulmonary embolism.
Clinical and biochemical response to elexacaftor/tezacaftor/ivacaftor in a patient with the rare L927P/N1303K CFTR genotype.
A 25-year-old woman with advanced cystic fibrosis and the rare L927P/N1303K CFTR genotype showed significant clinical improvement after starting elexacaftor/tezacaftor/ivacaftor (ETI).
Extracorporeal Membrane Oxygenation for Pneumocystis jirovecii Pneumonia in a Child With Multisystem Langerhans Cell Histiocytosis.
A 3-year-old boy with multisystem Langerhans cell histiocytosis developed severe Pneumocystis jirovecii pneumonia during treatment.
Sustained Mayer-Like Very-Low-Frequency Blood Pressure Oscillations in a 16-Year-Old After Drowning Associated Lung Injury.
A 16-year-old male with no prior health issues presented to the pediatric intensive care unit following drowning-associated lung injury, requiring mechanical ventilation for severe hypoxemia and pulmonary hemorrhage.
Targeting TIME With Phytochemicals: A Promising Approach Against Lung Cancer.
This systematic review investigates the role of phytochemicals in targeting the tumour immune microenvironment (TIME) in lung cancer.
Effectiveness of short-acting beta-2 agonists delivered by metered-dose inhaler with spacer versus nebulizer in acute asthma exacerbations: a systematic review and meta-analysis.
This systematic review and meta-analysis compared short-acting beta-2 agonists delivered by metered-dose inhaler (MDI) with spacer versus nebulizer for acute asthma exacerbations.
Factors associated with intensive care professionals' ability to identify patient-ventilator asynchronies: A systematic review and meta-analysis.
This systematic review and meta-analysis examined factors influencing intensive care professionals' ability to identify patient-ventilator asynchronies, analyzing data from 12 studies with 4823 participants.
Comparison of Esketamine and Remifentanil Combined With Propofol for Painless Fiberoptic Bronchoscopy: A Randomized Controlled Trial.
This randomized controlled trial compared esketamine with remifentanil, each combined with propofol, for elective painless flexible fiberoptic bronchoscopy in 206 adults.
High-flow nasal oxygen versus standard care during flexible bronchoscopy in children under general anaesthesia-The BUFFALO randomised controlled pilot trial.
The BUFFALO study was a bi-centre, unmasked, randomised controlled pilot trial comparing nasal high-flow oxygen (NHF) with standard-care oxygen after anaesthesia induction for elective flexible bronchoscopy in children…
The SAVOIR study: protocol for the development and validation of a PAH knowledge questionnaire.
The SAVOIR study is a methodological clinical trial aimed at developing and validating a questionnaire to assess disease knowledge in patients with pulmonary arterial hypertension (PAH), particularly in…
Interferon-gamma release assays versus tuberculin skin test for latent tuberculosis infection positivity among healthcare workers and first responders: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated latent tuberculosis infection (LTBI) positivity among healthcare workers and first responders using interferon-gamma release assays (IGRAs) and tuberculin skin tests…
Short-term exposure to urban air pollution and asthma-related morbidity in children under five: a PRISMA-guided systematic review with narrative synthesis (2021-2025).
This systematic review examined the impact of short-term urban air pollution exposure on asthma-related morbidity in children under five.
Low-Dose CO 2 Inhalation to Improve Oxygenation and Exercise Capacity at High Altitude: A Double-Blind Pilot Study.
This randomized controlled trial investigated the effects of 2.5% CO2 inhalation on oxygenation and exercise capacity in 28 healthy lowlanders at high altitude (4505 m).
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